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BioGRID | Network Layout for PTPN6 for Homo sapiens
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PTPN6

 Homo sapiens
The BioGRID Database Seperator
Aliases: HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1, EG5777
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: 70 kda SHP-1L protein|hematopoietic cell phosphatase|hematopoietic cell protein-tyrosine phosphatase|protein-tyrosine phosphatase 1C; protein tyrosine phosphatase, non-receptor type 6
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 12 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with PTPN6

PTPN6 was identified with 105 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 LAIR1
  • LAIR-1
  • CD305
  • XXbac-BCX...
    		•  The BioGRID Database Seperator leukocyte-associated immunoglobulin-like receptor 1; leukocyte-associated Ig-like receptor 1
    Gene Ontology: [View List]
    Invitro
    hit Meyaard L (1997)
    hit Xu M (2000)
    Two-hybrid
    hit Sathish JG (2001)
    Affinity Capture-Western
    hit Sathish JG (2001)
    bait Fournier N (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCK
  • YT16
  • p56lck
  • pp58lck
  • EG3932
    		•  The BioGRID Database Seperator T-lymphocyte specific protein tyrosine kinase p56lck|p56(LSTRA) protein-tyrosine kinase|protein tyrosine kinase|proto-oncogene tyrosine-protein kinase LCK; lymphocyte-specific protein tyrosine kinase
    Gene Ontology: [View List]
    Invivo
    hit Lorenz U (1994)
    hit Chiang GG (2001)
    Invitro
    hit Lorenz U (1994)
    hit Chiang GG (2001)
    Biochemical Activity
    hit Yu CL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Invitro
    hit Saci A (2002)
    Invivo
    hit Saci A (2002)
    Affinity Capture-Western
    bait Ganju RK (2000)
    bait Kon-Kozlowski M (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIT
  • C-Kit
  • CD117
  • PBT
  • EG3815
    		•  The BioGRID Database Seperator mast/stem cell growth factor receptor|proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kozlowski M (1998)
    hit Yi T (1993)
    Reconstituted Complex
    bait Kozlowski M (1998)
    hit Yi T (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSF2RB
  • CD131
  • CDw131
  • IL3RB
  • EG1439
    		•  The BioGRID Database Seperator Colony-stimulating factor-2 receptor, beta, low-affinity|interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Bone H (1997)
    bait Yi T (1993)
    Reconstituted Complex
    bait Bone H (1997)
    hit Yi T (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD22
  • SIGLEC-2
  • MGC130020
  • SIGLEC2
  • EG933
    		•  The BioGRID Database Seperator CD22 molecule; CD22 antigen
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Blasioli J (1999)
    bait Otipoby KL (2001)
    bait Greer SF (1999)
    Biochemical Activity
    hit Blasioli J (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PECAM1
  • CD31
  • PECAM-1
  • EG5175
    		•  The BioGRID Database Seperator platelet/endothelial cell adhesion molecule (CD31 antigen); CD31/EndoCAM|PECAM-1, CD31/EndoCAM|adhesion molecule
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Pumphrey NJ (1999)
    bait Hua CT (1998)
    Far Western
    bait Pumphrey NJ (1999)
    Affinity Capture-Western
    bait Hua CT (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSTR2
  • EG6752
    		•  The BioGRID Database Seperator somatostatin receptor 2
    Gene Ontology: [View List]
    Invivo
    bait Oomen SP (2001)
    Invitro
    bait Oomen SP (2001)
    Affinity Capture-Western
    hit Lopez F (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2B
  • CADTK
  • CAKB
  • FADK2
  • EG2185
    		•  The BioGRID Database Seperator CAK beta|calcium-dependent tyrosine kinase|cell adhesion kinase beta|focal adhesion kinase 2|proline-rich tyrosine kinase 2|protein kinase B|protein tyrosine kinase 2 beta|related adhesion focal tyrosine kinase; PTK2B protein tyrosine kinase 2 beta
    Gene Ontology: [View List]
    Invivo
    bait Kumar S (1999)
    Invitro
    bait Kumar S (1999)
    Affinity Capture-Western
    bait/hit Ganju RK (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROS1
  • MCF3
  • ROS
  • RP1-179P9.1
    		•  The BioGRID Database Seperator OTTHUMP00000040389|proto-oncogene c-ros-1 protein|proto-oncogene tyrosine-protein kinase ROS|transmembrane tyrosine-specific protein kinase|v-ros avian UR2 sarcoma virus oncogene homolog 1; v-ros UR2 sarcoma virus oncogene homolog 1 (avian)
    Gene Ontology: [View List]
    Two-hybrid
    bait Keilhack H (2001)
    Biochemical Activity
    hit Keilhack H (2001)
    Affinity Capture-Western
    bait/hit Keilhack H (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HOXA10
  • HOX1
  • HOX1.8
  • HOX1H
  • EG3206
    		•  The BioGRID Database Seperator homeo box A10|homeobox protein 1H|homeobox protein HOXA10; homeobox A10
    Gene Ontology: [View List]
    Biochemical Activity
    hit Eklund EA (2002)
    Reconstituted Complex
    hit Eklund EA (2002)
    Affinity Capture-Western
    hit Eklund EA (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Tomic S (1995)
    hit Keilhack H (1998)
    Reconstituted Complex
    hit Keilhack H (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYK
  • EG6850
    		•  The BioGRID Database Seperator spleen tyrosine kinase
    Gene Ontology: [View List]
    Invivo
    bait Dustin LB (1999)
    bait Adachi T (2001)
    Affinity Capture-Western
    hit Ganju RK (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD72
  • LYB2
  • CD72b
  • RP11-331F...
    		•  The BioGRID Database Seperator CD72 antigen|OTTHUMP00000045360; CD72 molecule
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ishida I (2003)
    bait Adachi T (1998)
    Reconstituted Complex
    bait Adachi T (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLEC4A
  • CLECSF6
  • DCIR
  • DDB27
  • EG50856
    		•  The BioGRID Database Seperator C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6|dendritic cell immunoreceptor|lectin-like immunoreceptor; C-type lectin domain family 4, member A
    Gene Ontology: [View List]
    Invitro
    bait Huang X (2001)
    Invivo
    bait Huang X (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD33
  • FLJ00391
  • SIGLEC-3
  • p67
  • EG945
    		•  The BioGRID Database Seperator CD33 antigen|CD33 antigen (gp67); CD33 molecule
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Taylor VC (1999)
    Reconstituted Complex
    bait Taylor VC (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TYK2
  • JTK1
  • EG7297
    		•  The BioGRID Database Seperator tyrosine kinase 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Yetter A (1995)
    Biochemical Activity
    hit Yetter A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCP2
  • SLP-76
  • SLP76
  • EG3937
    		•  The BioGRID Database Seperator 76 kDa tyrosine phosphoprotein|SH2 domain-containing leukocyte protein of 76kD|lymphocyte cytosolic protein 2|lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
    Gene Ontology: [View List]
    Invitro
    hit Mizuno K (1996)
    Reconstituted Complex
    hit Binstadt BA (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZAP70
  • SRK
  • STD
  • TZK
  • EG7535
    		•  The BioGRID Database Seperator syk-related tyrosine kinase|zeta-chain (TCR) associated protein kinase (70 kD)|zeta-chain associated protein kinase 70kDa|zeta-chain associated protein kinase, 70kD; zeta-chain (TCR) associated protein kinase 70kDa
    Gene Ontology: [View List]
    Invitro
    bait Plas DR (1996)
    bait Brockdorff J (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPOR
  • MGC138358
  • EG2057
    		•  The BioGRID Database Seperator erythropoietin receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Klingmuller U (1995)
    Reconstituted Complex
    hit Klingmuller U (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTNND1
  • CAS
  • CTNND
  • KIAA0384
  • EG1500
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), delta 1; catenin, delta 1
    Gene Ontology: [View List]
    Invivo
    hit Keilhack H (2000)
    Invitro
    hit Keilhack H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BLNK
  • BLNK-s
  • Ly57
  • SLP-65
  • EG29760
    		•  The BioGRID Database Seperator B cell linker protein|B-cell linker protein; B-cell linker
    Gene Ontology: [View List]
    Invivo
    bait Adachi T (2001)
    Invitro
    bait Adachi T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCD
  • MAY1
  • MGC49908
  • nPKC-delta
  • EG5580
    		•  The BioGRID Database Seperator protein kinase C, delta
    Gene Ontology: [View List]
    Invivo
    bait Yoshida K (2001)
    Invitro
    bait Yoshida K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PILRA
  • FDF03
  • EG29992
    		•  The BioGRID Database Seperator cell surface receptor FDF03|inhibitory receptor PILRalpha|paired immunoglobin-like receptor alpha|paired immunoglobulin-like receptor alpha|paired immunoglobulin-like type 2 receptor alpha; paired immunoglobin-like type 2 receptor alpha
    Gene Ontology: [View List]
    Invivo
    bait Mousseau DD (2000)
    Affinity Capture-Western
    bait Fournier N (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCR
  • ALL
  • BCR1
  • CML
  • EG613
    		•  The BioGRID Database Seperator breakpoint cluster region protein; breakpoint cluster region
    Gene Ontology: [View List]
    Invivo
    hit Ram PA (1997)
    Affinity Capture-Western
    bait/hit Liedtke M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LILRB2
  • CD85D
  • ILT4
  • LIR-2
  • XXbac-BCX...
    		•  The BioGRID Database Seperator Ig-like transcript 4|immunoglobulin-like transcript 4|leukocyte immunoglobulin-like receptor 2|leukocyte immunoglobulin-like receptor, subfamily B, member 2|monocyte/macrophage immunoglobulin-like receptor 10; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
    Gene Ontology: [View List]
    Invitro
    bait Fanger NA (1998)
    bait Colonna M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLAMF6
  • KALI
  • KALIb
  • Ly108
  • EG114836
    		•  The BioGRID Database Seperator NTBA receptor|activating NK receptor|natural killer-, T- and B-cell antigen; SLAM family member 6
    Gene Ontology: [View List]
    Invivo
    bait Bottino C (2001)
    Invitro
    bait Bottino C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GHR
  • GHBP
  • EG2690
    		•  The BioGRID Database Seperator growth hormone binding protein|serum binding protein|somatotropin receptor; growth hormone receptor
    Gene Ontology: [View List]
    Invivo
    bait Moutoussamy S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAB2
  • KIAA0571
  • EG9846
    		•  The BioGRID Database Seperator GRB2-associated binding protein 2; Grb2-associated binder 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yu WM (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOS1
  • NOS
  • IHPS1
  • EG4842
    		•  The BioGRID Database Seperator nitric oxide synthase 1 (neuronal); neuronal nitric oxide synthase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Lopez F (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAG1
  • CBP
  • FLJ37858
  • PAG
  • EG55824
    		•  The BioGRID Database Seperator Csk-binding protein|phosphoprotein associated with glycosphingolipid-enriched microdomains; phosphoprotein associated with glycosphingolipid microdomains 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Brdicka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAV1
  • CAV
  • MSTP085
  • VIP21
  • EG857
    		•  The BioGRID Database Seperator caveolae protein, 22-kD|caveolin 1|caveolin 1 caveolae protein, 22kD|caveolin 1, alpha isoform|caveolin 1, beta isoform|cell growth-inhibiting protein 32; caveolin 1, caveolae protein, 22kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Caselli A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD5
  • LEU1
  • T1
  • EG921
    		•  The BioGRID Database Seperator CD5 antigen (p56-62); CD5 molecule
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Perez-Villar JJ (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOS1
  • GF1
  • GGF1
  • GINGF
  • EG6654
    		•  The BioGRID Database Seperator gingival fibromatosis, hereditary, 1|son of sevenless homolog 1; son of sevenless homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western