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BioGRID | Network Layout for PTK2 for Homo sapiens
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PTK2

 Homo sapiens
The BioGRID Database Seperator
Aliases: FADK, FAK, FAK1, pp125FAK, EG5747
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: PTK2 protein tyrosine kinase 2; focal adhesion kinase 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 4 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with PTK2

PTK2 was identified with 107 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 PXN
  • FLJ16691
  • hCG_1778014
    		•  The BioGRID Database Seperator paxillin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kovacic-Milivojevi? B (2001)
    hit Liu S (2002)
    hit Zheng C (1998)
    Reconstituted Complex
    hit Matsuya M (1998)
    bait Turner CE (1999)
    hit Liu S (2002)
    bait Mazaki Y (1997)
    bait Brown MC (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Invivo
    hit Schlaepfer DD ()
    Invitro
    hit Schlaepfer DD ()
    Affinity Capture-Western
    bait Sieg DJ (2000)
    hit Messina S (2003)
    Reconstituted Complex
    bait Angers-Loustau A (1999)
    bait Hildebrand JD (1996)
    bait Arold ST (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEDD9
  • CAS-L
  • CASL
  • HEF1
  • EG4739
    		•  The BioGRID Database Seperator Crk-associated substrate related|cas-like docking|dJ49G10.2 (Enhancer of Filamentation 1 (HEF1))|dJ761I2.1 (enhancer of filamentation (HEF1))|enhancer of filamentation 1; neural precursor cell expressed, developmentally down-regulated 9
    Gene Ontology: [View List]
    Invivo
    bait Zhang Z (1999)
    Invitro
    bait Zhang Z (1999)
    Two-hybrid
    bait Zhang Z (1999)
    hit Law SF (1996)
    Affinity Capture-Western
    bait Law SF (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Hsia DA (2003)
    bait Hecker TP (2002)
    hit Relou IA (2003)
    hit Messina S (2003)
    Reconstituted Complex
    bait Angers-Loustau A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TGFB1I1
  • ARA55
  • HIC-5
  • HIC5
  • EG7041
    		•  The BioGRID Database Seperator transforming growth factor beta 1 induced transcript 1; androgen receptor coactivator ARA55
    Gene Ontology: [View List]
    Invivo
    bait Fujita H (1998)
    Invitro
    bait Fujita H (1998)
    Reconstituted Complex
    hit Matsuya M (1998)
    bait Thomas SM (1999)
    Affinity Capture-Western
    bait Nishiya N (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCAR1
  • CAS
  • CRKAS
  • P130Cas
  • EG9564
    		•  The BioGRID Database Seperator breast cancer anti-estrogen resistance 1; Crk-associated substrate p130Cas
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Salgia R (1996)
    hit Hsia DA (2003)
    bait Chellaiah MA (2001)
    Reconstituted Complex
    bait Hildebrand JD (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIT1
  • EG28964
    		•  The BioGRID Database Seperator G protein-coupled receptor kinase interactor 1; G protein-coupled receptor kinase-interactor 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ko J (2003)
    bait/hit Kim S (2003)
    bait Zhao ZS (2000)
    Reconstituted Complex
    bait Zhao ZS (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Invivo
    hit Retta SF (1996)
    Invitro
    hit Retta SF (1996)
    Affinity Capture-Western
    hit Mañes S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TLN1
  • KIAA1027
  • TLN
  • ILWEQ
  • EG7094
    		•  The BioGRID Database Seperator talin 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chen HC (1995)
    hit Zheng C (1998)
    Reconstituted Complex
    bait Chen HC (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RB1CC1
  • CC1
  • DRAGOU14
  • FIP200
  • EG9821
    		•  The BioGRID Database Seperator 200 kDa FAK family kinase-interacting protein|Rb1-inducible coiled coil protein 1; RB1-inducible coiled-coil 1
    Gene Ontology: [View List]
    Invivo
    hit Ueda H (2000)
    Invitro
    hit Ueda H (2000)
    Two-hybrid
    hit Ueda H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ITGB3
  • CD61
  • GP3A
  • GPIIIa
  • EG3690
    		•  The BioGRID Database Seperator integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); integrin beta chain, beta 3|platelet glycoprotein IIIa
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Eliceiri BP (2002)
    Affinity Capture-Western
    bait Chung J (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ITGB5
  • FLJ26658
  • EG3693
    		•  The BioGRID Database Seperator integrin, beta 5
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Eliceiri BP (2002)
    Affinity Capture-Western
    bait Eliceiri BP (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CRK
  • CRKII
  • EG1398
    		•  The BioGRID Database Seperator avian sarcoma virus CT10 (v-crk) oncogene homolog|v-crk avian sarcoma virus CT10 oncogene homolog|v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Hsia DA (2003)
    Reconstituted Complex
    bait Angers-Loustau A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSK
  • MGC117393
  • EG1445
    		•  The BioGRID Database Seperator c-src tyrosine kinase
    Gene Ontology: [View List]
    Invivo
    bait Bergman M (1995)
    Invitro
    bait Bergman M (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSC2
  • LAM
  • TSC4
  • FLJ43106
  • EG7249
    		•  The BioGRID Database Seperator tuberous sclerosis 2; tuberin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Gan B (2006)
    Reconstituted Complex
    bait/hit Gan B (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMX
  • ETK
  • PSCTK2
  • PSCTK3
  • EG660
    		•  The BioGRID Database Seperator BMX non-receptor tyrosine kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chen R (2001)
    Reconstituted Complex
    bait Chen R (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT1
  • DKFZp686B...
  • ISGF-3
  • STAT91
  • EG6772
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 1|signal transducer and activator of transcription-1|transcription factor ISGF-3 components p91/p84; signal transducer and activator of transcription 1, 91kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Xie B (2001)
    Reconstituted Complex
    bait Xie B (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FYN
  • MGC45350
  • SLK
  • SYN
  • RP1-66H14.1
    		•  The BioGRID Database Seperator OKT3-induced calcium influx regulator|c-syn protooncogene|protein-tyrosine kinase fyn|proto-oncogene tyrosine-protein kinase fyn|src-like kinase|src/yes-related novel|tyrosine kinase p59fyn(T); FYN oncogene related to SRC, FGR, YES
    Gene Ontology: [View List]
    Invitro
    hit Arold ST (2001)
    Affinity Capture-Western
    hit Messina S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK2
  • EG3717
    		•  The BioGRID Database Seperator Janus kinase 2|OTTHUMP00000043260|tyrosine-protein kinase JAK2; Janus kinase 2 (a protein tyrosine kinase)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Zhu T (1998)
    hit Ryu H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R1
  • GRB1
  • p85-ALPHA
  • EG5295
    		•  The BioGRID Database Seperator phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit, polypeptide 1|phosphoinositide-3-kinase, regulatory subunit, polypeptide...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Guinebault C (1995)
    Far Western
    hit Guinebault C (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DCC
  • CRC18
  • CRCR1
  • EG1630
    		•  The BioGRID Database Seperator deleted in colorectal cancer protein; deleted in colorectal carcinoma
    Gene Ontology: [View List]
    Two-hybrid
    bait Ren XR (2004)
    Affinity Capture-Western
    bait Ren XR (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYK
  • EG6850
    		•  The BioGRID Database Seperator spleen tyrosine kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Chung J (1997)
    hit Sada K (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB7
  • EG2886
    		•  The BioGRID Database Seperator growth factor receptor-bound protein 7
    Gene Ontology: [View List]
    Invivo
    hit Han DC (1999)
    Invitro
    hit Han DC (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ITGA4
  • CD49D
  • IA4
  • MGC90518
  • EG3676
    		•  The BioGRID Database Seperator 269C wild type|antigen CD49D, alpha-4 subunit of VLA-4 receptor|integrin alpha 4|integrin alpha-4 subunit|very late activation protein 4 receptor, alpha 4 subunit; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Liu S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2
  • FADK
  • FAK
  • FAK1
  • EG5747
    		•  The BioGRID Database Seperator PTK2 protein tyrosine kinase 2; focal adhesion kinase 1
    Gene Ontology: [View List]
    Co-crystal Structure
    hit Arold ST (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGAP26
  • GRAF
  • KIAA0621
  • OPHN1L
  • EG23092
    		•  The BioGRID Database Seperator GTPase regulator associated with FAK|GTPase regulator associated with focal adhesion kinase pp125(FAK)|GTPase regulator associated with the focal adhesion kinase pp125; Rho GTPase activating protein 26
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Hildebrand JD (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPHA2
  • ECK
  • EG1969
    		•  The BioGRID Database Seperator ephrin receptor EphA2|epithelial cell receptor protein tyrosine kinase|protein tyrosine kinase|receptor protein tyrosine kinase regulated by p53 and E2F-1; EPH receptor A2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Miao H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCK1
  • MGC12668
  • NCK
  • NCKalpha
  • EG4690
    		•  The BioGRID Database Seperator NCK tyrosine kinase|SH2/SH3 adaptor protein NCK-alpha|melanoma NCK protein|non-catalytic region of tyrosine kinase; NCK adaptor protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Minegishi M (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IGF1R
  • JTK13
  • CD221
  • IGFIR
  • EG3480
    		•  The BioGRID Database Seperator insulin-like growth factor 1 receptor; clone 1900 unknown protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Mañes S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP1CB
  • MGC3672
  • PP-1B
  • PPP1CD
  • EG5500
    		•  The BioGRID Database Seperator protein phosphatase 1, catalytic subunit, beta|protein phosphatase 1, catalytic subunit, delta isoform|protein phosphatase 1-beta|protein phosphatase 1-delta|serine/threonine protein phosphatase PP1-beta catalytic subunit; protein phosphatase 1, catalytic subunit, beta isoform
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Fresu M (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YES1
  • HsT441
  • P61-YES
  • Yes
  • EG7525
    		•  The BioGRID Database Seperator Yamaguchi sarcoma oncogene|cellular yes-1 protein|proto-oncogene tyrosine-protein kinase YES|viral oncogene yes-1 homolog 1; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Messina S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BIN1
  • AMPH2
  • AMPHL
  • DKFZp547F...
  • EG274
    		•  The BioGRID Database Seperator amphiphysin II|amphiphysin-like|box dependant MYC interacting protein 1; bridging integrator 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Messina S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG1
  • PLC-II
  • PLC1
  • PLC148
  • EG5335
    		•  The BioGRID Database Seperator 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phosphol...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zhang X (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSN
  • DKFZp313L...
  • RP11-477J...
    		•  The BioGRID Database Seperator gelsolin (amyloidosis, Finnish type); gelsolin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chellaiah MA (2001)