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BioGRID | Network Layout for PSEN1 for Homo sapiens
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PSEN1

 Homo sapiens
The BioGRID Database Seperator
Aliases: AD3, FAD, PS1, S182, EG5663
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: presenilin 1 (Alzheimer disease 3); presenilin 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 18 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with PSEN1

PSEN1 was identified with 82 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 CTNND2
  • GT24
  • NPRAP
  • EG1501
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
    Gene Ontology: [View List]
    Invivo
    hit Zhou J (1997)
    hit Tanahashi H (1999)
    hit Levesque G (1999)
    Invitro
    hit Zhou J (1997)
    hit Tanahashi H (1999)
    hit Levesque G (1999)
    Two-hybrid
    hit Zhou J (1997)
    hit Tanahashi H (1999)
    hit Levesque G (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PKP4
  • p0071
  • FLJ31261
  • FLJ42243
  • EG8502
    		•  The BioGRID Database Seperator plakophilin 4; catenin 4
    Gene Ontology: [View List]
    Invivo
    hit Levesque G (1999)
    Invitro
    hit Levesque G (1999)
    Two-hybrid
    hit Levesque G (1999)
    hit Stahl B (1999)
    Affinity Capture-Western
    hit Stahl B (1999)
    Reconstituted Complex
    hit Stahl B (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APH1A
  • 6530402N0...
  • APH-1A
  • CGI-78
  • EG51107
    		•  The BioGRID Database Seperator anterior pharynx defective 1 homolog A (C. elegans); anterior pharynx defective 1 homolog A
    Gene Ontology: [View List]
    Invivo
    bait Lee SF (2002)
    Invitro
    bait Lee SF (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait/hit Baulac S (2003)
    bait/hit Gu Y (2003)
    Co-fractionation
    bait Gu Y (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTNNB1
  • CTNNB
  • FLJ25606
  • DKFZp686D...
  • EG1499
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), beta 1 (88kD)|catenin (cadherin-associated protein), beta 1 (88kDa; catenin (cadherin-associated protein), beta 1, 88kDa
    Gene Ontology: [View List]
    Invivo
    hit Murayama M (1998)
    Invitro
    hit Murayama M (1998)
    Affinity Capture-Western
    hit Tesco G (1998)
    hit Kang DE (1999)
    bait Murayama M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSENEN
  • MDS033
  • MSTP064
  • PEN2
  • EG55851
    		•  The BioGRID Database Seperator hematopoietic stem/progenitor cells protein MDS033|presenilin enhancer 2; presenilin enhancer 2 homolog (C. elegans)
    Gene Ontology: [View List]
    Invivo
    bait Steiner H (2002)
    Invitro
    bait Steiner H (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait/hit Baulac S (2003)
    hit Crystal AS (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBQLN1
  • DA41
  • DSK2
  • FLJ90054
  • EG29979
    		•  The BioGRID Database Seperator ubiquilin 1
    Gene Ontology: [View List]
    Invitro
    bait Mah AL (2000)
    Invivo
    bait Mah AL (2000)
    Two-hybrid
    bait Mah AL (2000)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCSTN
  • APH2
  • KIAA0253
  • RP11-517F...
  • EG23385
    		•  The BioGRID Database Seperator ATAG1874|anterior pharynx-defective 2; nicastrin
    Gene Ontology: [View List]
    Invivo
    hit Yu G (2000)
    Affinity Capture-Western
    bait Haffner C (2004)
    bait/hit Baulac S (2003)
    bait/hit Gu Y (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ICAM5
  • TLCN
  • TLN
  • EG7087
    		•  The BioGRID Database Seperator intercellular adhesion molecule 5, telencephalin; intercellular adhesion molecule 5|telencephalin
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Annaert WG (2001)
    Two-hybrid
    hit Annaert WG (2001)
    Reconstituted Complex
    hit Annaert WG (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GFAP
  • FLJ45472
  • EG2670
    		•  The BioGRID Database Seperator glial fibrillary acidic protein; intermediate filament protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Two-hybrid
    hit Nielsen AL (2002)
    Reconstituted Complex
    hit Nielsen AL (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2
  • Bcl-2
  • EG596
    		•  The BioGRID Database Seperator B-cell lymphoma protein 2; B-cell CLL/lymphoma 2
    Gene Ontology: [View List]
    Invivo
    hit Alberici A (1999)
    Invitro
    hit Alberici A (1999)
    Two-hybrid
    hit Alberici A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSEN
  • DREAM
  • KCHIP3
  • KCNIP3
  • EG30818
    		•  The BioGRID Database Seperator A-type potassium channel modulatory protein 3|DRE-antagonist modulator|Kv channel interacting protein 3|calsenilin, presenilin-binding protein, EF hand transcription factor|potassium channel interacting protein 3; Kv channel interacting protein 3, calsenilin
    Gene Ontology: [View List]
    Invivo
    hit Zaidi NF (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Buxbaum JD (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2L1
  • BCL-XL/S
  • BCL2L
  • BCLX
  • EG598
    		•  The BioGRID Database Seperator BCL2-like 1
    Gene Ontology: [View List]
    Invivo
    bait Passer BJ (1999)
    Two-hybrid
    bait Passer BJ (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTNNA1
  • CAP102
  • FLJ36832
  • EG1495
    		•  The BioGRID Database Seperator alpha-E-catenin|alpha-catenin|alphaE-catenin|cadherin-associated protein,102kDa|catenin (cadherin-associated protein), alpha 1 (102kD)|catenin, alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa
    Gene Ontology: [View List]
    Invivo
    hit Georgakopoulos A (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSEN1
  • AD3
  • FAD
  • PS1
  • EG5663
    		•  The BioGRID Database Seperator presenilin 1 (Alzheimer disease 3); presenilin 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Hebert SS (2003)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FLNB
  • ABP-278
  • AOI
  • DKFZp686A...
  • EG2317
    		•  The BioGRID Database Seperator beta filamin|filamin 1 (actin-binding protein-280)-like|filamin B variant 2|filamin B, beta (actin-binding protein-278); filamin B, beta (actin binding protein 278)
    Gene Ontology: [View List]
    Two-hybrid
    hit Zhang W (1998)
    Reconstituted Complex
    bait Zhang W (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOCK3
  • KIAA0299
  • MOCA
  • PBP
  • EG1795
    		•  The BioGRID Database Seperator dedicator of cyto-kinesis 3|modifier of cell adhesion|presenilin-binding protein; dedicator of cytokinesis 3
    Gene Ontology: [View List]
    Invitro
    hit Kashiwa A (2000)
    Two-hybrid
    hit Kashiwa A (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOTCH1
  • TAN1
  • hN1
  • EG4851
    		•  The BioGRID Database Seperator neurogenic locus notch homolog protein 1|notch1|translocation-associated notch protein TAN-1; Notch homolog 1, translocation-associated (Drosophila)
    Gene Ontology: [View List]
    Invivo
    bait Ray WJ (1999)
    bait De Strooper B (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HERPUD1
  • HERP
  • KIAA0025
  • Mif1
  • EG9709
    		•  The BioGRID Database Seperator MMS-inducible|homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein|methyl methanesulfonate (MMF)-inducible fragment protein 1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
    Gene Ontology: [View List]
    Invivo
    bait Sai X (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERN1
  • FLJ30999
  • IRE1
  • IRE1P
  • EG2081
    		•  The BioGRID Database Seperator ER to nucleus signalling 1|endoplasmic reticulum to nucleus signalling 1|inositol-requiring 1|protein kinase/endoribonuclease; endoplasmic reticulum to nucleus signaling 1
    Gene Ontology: [View List]
    Invivo
    bait Katayama T (1999)
    Invitro
    bait Katayama T (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APP
  • AAA
  • ABETA
  • ABPP
  • EG351
    		•  The BioGRID Database Seperator A4 amyloid protein|amyloid beta A4 protein|amyloid-beta protein|beta-amyloid peptide|cerebral vascular amyloid peptide|protease nexin-II; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
    Gene Ontology: [View List]
    Invitro
    bait Ray WJ (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Ctnnb1
  • Catnb
  • Mesc
  • EG12387
    		•  The BioGRID Database Seperator beta catenin|beta-catenin|cadherin associated protein|catenin (cadherin associated protein), beta 1, 88kDa|catenin (cadherin-associated protein), beta 1, 88kDa|catenin beta; catenin (cadherin associated protein), beta 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Xia X (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FBXW7
  • AGO
  • CDC4
  • DKFZp686F...
  • EG55294
    		•  The BioGRID Database Seperator F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)|F-box protein FBW7|F-box protein SEL-10|archipelago homolog|archipelago, Drosophila, homolog of|homolog of C elegans sel-10; F-box and WD repeat domain containing 7
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Li J (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSEN2
  • AD3L
  • AD4
  • PS2
  • EG5664
    		•  The BioGRID Database Seperator Alzheimer's disease 3-like|presenilin 2; presenilin 2 (Alzheimer disease 4)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Gu Y (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLSTN1
  • CSTN1
  • KIAA0911
  • PIK3CD
  • EG22883
    		•  The BioGRID Database Seperator alcadein alpha 1|non-classical cadherin XB31alpha1; calsyntenin 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Araki Y (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TCF7L2
  • TCF-4
  • TCF4
  • RP11-357H...
    		•  The BioGRID Database Seperator transcription factor 7-like 2 (T-cell specific, HMG-box)
    Gene Ontology: [View List]
    Invitro
    bait Palacino JJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     METTL2
  • FLJ11350
  • METL
  • PSENIP1
  • EG55798
    		•  The BioGRID Database Seperator methyltransferase like 2B
    Gene Ontology: [View List]
    Two-hybrid
    hit Zhang SX (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPT
  • DDPAC
  • FLJ31424
  • FTDP-17
  • EG4137
    		•  The BioGRID Database Seperator G protein beta1/gamma2 subunit-interacting factor 1|microtubule-associated protein tau, isoform 4; microtubule-associated protein tau
    Gene Ontology: [View List]
    Invivo
    hit Takashima A (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDH1
  • Arc-1
  • CDHE
  • ECAD
  • EG999
    		•  The BioGRID Database Seperator cadherin 1, E-cadherin (epithelial)|cadherin 1, type 1|calcium-dependent adhesion protein, epithelial|cell-CAM 120/80|uvomorulin; cadherin 1, type 1, E-cadherin (epithelial)
    Gene Ontology: [View List]
    Invitro
    bait Georgakopoulos A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YME1L1
  • FTSH
  • MEG4
  • PAMP
  • EG10730
    		•  The BioGRID Database Seperator ATP-dependent metalloprotease FtsH1 homolog|YME1 (S.cerevisiae)-like 1|YME1-like 1; YME1-like 1 (S. cerevisiae)
    Gene Ontology: [View List]
    Two-hybrid
    bait Pellegrini L (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAB11A
  • MGC1490
  • YL8
  • EG8766
    		•  The BioGRID Database Seperator RAB 11A, member oncogene family|Ras-related protein Rab-11A; RAB11A, member RAS oncogene family
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP3
  • CPP32
  • CPP32B
  • SCA-1
  • EG836
    		•  The BioGRID Database Seperator PARP cleavage protease|SREBP cleavage activity 1|Yama|apopain|caspase 3|caspase 3, apoptosis-related cysteine protease|cysteine protease CPP32|procaspase3; caspase 3, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP7
  • CMH-1
  • ICE-LAP3
  • MCH3
  • EG840
    		•  The BioGRID Database Seperator ICE-like apoptotic protease 3|Lice2 alpha/beta/gamma|apoptotic protease MCH-3|caspase 7|caspase 7, apoptosis-related cysteine protease; caspase 7, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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