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MAP2K2
Homo sapiens
Aliases:
MAPKK2, MEK2, MKK2, PRKMK2, EG5605
Description:
CFC syndrome|ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase 2
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
5 total GO annotations for this record.
[view list]
Function
Process
Component
•
ATP binding
(
NAS
)
•
protein binding
(
IPI
)
•
protein serine/threonine ...
(
NAS
)
•
protein amino acid phosph ...
(
NAS
)
•
extracellular region
(
NAS
)
Download interactions associated with MAP2K2
MAP2K2 was identified with
9
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
MAPK3
ERK1
P44ERK1
P44MAPK
EG5595
extracellular signal-regulated kinase 1|extracellular signal-related kinase 1; mitogen-activated protein kinase 3
Gene Ontology:
[View List]
Two-hybrid
hit
Marti A (1997)
Biochemical Activity
hit
Butch ER (1996)
bait/hit
Zheng CF (1993)
Reconstituted Complex
hit
Zheng CF (1993)
ARAF
A-RAF
ARAF1
PKS2
RP1-230G1.1
Oncogene ARAF1|Ras-binding protein DA-Raf|v-raf murine sarcoma 3611 viral oncogene homolog 1; v-raf murine sarcoma 3611 viral oncogene homolog
Gene Ontology:
[View List]
Invitro
hit
Yin XL (2002)
Two-hybrid
hit
Yin XL (2002)
MAP2K2
MAPKK2
MEK2
MKK2
EG5605
CFC syndrome|ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase 2
Gene Ontology:
[View List]
Biochemical Activity
bait/hit
Zheng CF (1993)
MAPK1
ERK
ERK2
ERT1
EG5594
extracellular signal-regulated kinase 2|extracellular signal-regulated kinase-2|mitogen-activated protein kinase 2|protein tyrosine kinase ERK2; mitogen-activated protein kinase 1
Gene Ontology:
[View List]
Two-hybrid
hit
Robinson FL (2002)
Flna
ABP-280
F730004A1...
Fln1
EG192176
GENA 379|actin-binding protein 280|dilated pupils 2|filamin A; filamin, alpha
Gene Ontology:
[View List]
Two-hybrid
hit
Marti A (1997)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.