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BioGRID | Network Layout for MAP2K1 for Homo sapiens
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MAP2K1

 Homo sapiens
The BioGRID Database Seperator
Aliases: MAPKK1, MEK1, MKK1, PRKMK1, EG5604
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); mitogen-activated protein kinase kinase 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 5 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MAP2K1

MAP2K1 was identified with 40 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MAPK1
  • ERK
  • ERK2
  • ERT1
  • EG5594
    		•  The BioGRID Database Seperator extracellular signal-regulated kinase 2|extracellular signal-regulated kinase-2|mitogen-activated protein kinase 2|protein tyrosine kinase ERK2; mitogen-activated protein kinase 1
    Gene Ontology: [View List]
    Invivo
    bait Xu Be (2001)
    bait Robinson MJ (2002)
    Invitro
    bait Xu Be (2001)
    bait Robinson MJ (2002)
    Two-hybrid
    bait Xu Be (2001)
    bait Robinson MJ (2002)
    hit Robinson FL (2002)
    Affinity Capture-Western
    bait Sanz-Moreno V (2003)
    Biochemical Activity
    hit Sanz-Moreno V (2003)
    Reconstituted Complex
    bait/hit Yeung K (2000)
    bait Wunderlich W (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK3
  • ERK1
  • P44ERK1
  • P44MAPK
  • EG5595
    		•  The BioGRID Database Seperator extracellular signal-regulated kinase 1|extracellular signal-related kinase 1; mitogen-activated protein kinase 3
    Gene Ontology: [View List]
    Invivo
    bait Yung Y (2000)
    bait Zheng CF (1993)
    Invitro
    bait Yung Y (2000)
    bait Zheng CF (1993)
    Two-hybrid
    hit Marti A (1997)
    Biochemical Activity
    hit Butch ER (1996)
    Affinity Capture-Western
    bait Schaeffer HJ (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB10
  • GRB-IR
  • IRBP
  • KIAA0207
  • EG2887
    		•  The BioGRID Database Seperator GRB10 adaptor protein|maternally expressed gene 1; growth factor receptor-bound protein 10
    Gene Ontology: [View List]
    Two-hybrid
    hit Nantel A (1998)
    Reconstituted Complex
    hit Nantel A (1998)
    Affinity Capture-Western
    bait/hit Nantel A (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8IP3
  • DKFZp762N...
  • FLJ00027
  • JIP3
  • AC012180.8
    		•  The BioGRID Database Seperator C-jun-amino-terminal kinase interacting protein 3|JNK-interacting protein 3|JNK/SAPK-associated protein-1|JNK/stress-activated protein kinase-associated protein 1|homolog of Drosophila Sunday driver 2; mitogen-activated protein kinase 8 interacting protein 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kuboki Y (2000)
    bait Ito M (1999)
    Reconstituted Complex
    bait Kuboki Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K1IP1
  • MP1
  • EG8649
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase 1 interacting protein 1; MEK binding partner 1|MEK partner 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Wunderlich W (2001)
    hit Schaeffer HJ (1998)
    Two-hybrid
    bait Schaeffer HJ (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEBP4
  • CORK-1
  • CORK1
  • GWTM1933
  • EG157310
    		•  The BioGRID Database Seperator phosphatidylethanolamine-binding protein 4; cousin-of-RKIP 1 protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Wang X (2004)
    Reconstituted Complex
    bait Wang X (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K4
  • KIAA0213
  • MAPKKK4
  • MEKK4
  • RP3-473J1...
    		•  The BioGRID Database Seperator MAP/ERK kinase kinase 4|MAPK/ERK kinase kinase 4|SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of|dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4)|predicted protein of HQ0412; mitogen-activated protein kinase kinase kinase 4
    Gene Ontology: [View List]
    Invitro
    bait Chan-Hui PY (1998)
    Invivo
    bait Chan-Hui PY (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K8
  • COT
  • EST
  • ESTF
  • EG1326
    		•  The BioGRID Database Seperator Cancer Osaka thyroid oncogene|Ewing sarcoma transformant|cot (cancer Osaka thyroid) oncogene|proto-oncogene serine/threoine protein kinase|tumor progression locus-2; mitogen-activated protein kinase kinase kinase 8
    Gene Ontology: [View List]
    Biochemical Activity
    bait Salmeron A (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K1
  • MAPKKK1
  • MEKK
  • MEKK1
  • EG4214
    		•  The BioGRID Database Seperator MAP/ERK kinase kinase 1|MAPK/ERK kinase kinase 1|MEK kinase 1; mitogen-activated protein kinase kinase kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Karandikar M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV1
  • VAV
  • EG7409
    		•  The BioGRID Database Seperator oncogene vav|vav 1 oncogene|vav proto-oncogene; vav 1 guanine nucleotide exchange factor
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Song JS (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HRAS
  • HRAS1
  • K-ras
  • N-ras
  • EG3265
    		•  The BioGRID Database Seperator H-RasIDX|c-has/bas p21 protein|c-ras-Ki-2 protein|p21 protein; v-Ha-ras Harvey rat sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Jelinek T (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PBP
  • RKIP
  • HCNP
  • PEBP
  • EG5037
    		•  The BioGRID Database Seperator Raf kinase inhibitory protein|prostatic binding protein; phosphatidylethanolamine binding protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Yeung K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KSR2
  • FLJ25965
  • EG283455
    		•  The BioGRID Database Seperator kinase suppressor of ras 2; kinase suppressor of Ras-2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Channavajhala PL (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Flna
  • ABP-280
  • F730004A1...
  • Fln1
  • EG192176
    		•  The BioGRID Database Seperator GENA 379|actin-binding protein 280|dilated pupils 2|filamin A; filamin, alpha
    Gene Ontology: [View List]
    Two-hybrid
    hit Marti A (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Yeung K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPBPIP
  • HSPC003
  • RP11-336K...
  • p14
  • EG28956
    		•  The BioGRID Database Seperator mitogen-activated protein-binding protein-interacting protein (MAPBPIP); mitogen-activated protein-binding protein-interacting protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Wunderlich W (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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