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BioGRID | Network Layout for MAPK3 for Homo sapiens
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MAPK3

 Homo sapiens
The BioGRID Database Seperator
Aliases: ERK1, P44ERK1, P44MAPK, PRKM3, HS44KDAP, HUMKER1A, MGC20180, EG5595
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: extracellular signal-regulated kinase 1|extracellular signal-related kinase 1; mitogen-activated protein kinase 3
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MAPK3

MAPK3 was identified with 64 protein interactions and 1 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MAP2K1
  • MAPKK1
  • MEK1
  • MKK1
  • EG5604
    		•  The BioGRID Database Seperator protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); mitogen-activated protein kinase kinase 1
    Gene Ontology: [View List]
    Invivo
    hit Yung Y (2000)
    hit Zheng CF (1993)
    Invitro
    hit Yung Y (2000)
    hit Zheng CF (1993)
    Two-hybrid
    bait Marti A (1997)
    Biochemical Activity
    bait Butch ER (1996)
    Affinity Capture-Western
    hit Schaeffer HJ (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN7
  • BPTP-4
  • HEPTP
  • LC-PTP
  • EG5778
    		•  The BioGRID Database Seperator dual specificity phosphatase 1|hematopoietic protein-tyrosine phosphatase|protein-tyrosine phoshatase, nonreceptor-type, stress induced; protein tyrosine phosphatase, non-receptor type 7
    Gene Ontology: [View List]
    Invivo
    hit Saxena M (1999)
    Invitro
    hit Saxena M (1999)
    Biochemical Activity
    bait Pettiford SM (2000)
    Reconstituted Complex
    bait Saxena M (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K2
  • MAPKK2
  • MEK2
  • MKK2
  • EG5605
    		•  The BioGRID Database Seperator CFC syndrome|ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase 2
    Gene Ontology: [View List]
    Invitro
    bait Zheng CF (1993)
    Two-hybrid
    bait Marti A (1997)
    Biochemical Activity
    bait Butch ER (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GTF2I
  • BAP-135
  • BAP135
  • BTKAP1
  • EG2969
    		•  The BioGRID Database Seperator BTK-associated protein, 135kD|Bruton tyrosine kinase-associated protein 135|Williams-Beuren syndrome chromosome region 6; general transcription factor II, i
    Gene Ontology: [View List]
    Invivo
    hit Kim DW (2000)
    Invitro
    hit Kim DW (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA2
  • HU-2
  • MAPKAPK1C
  • RSK
  • EG6196
    		•  The BioGRID Database Seperator ribosomal S6 kinase 3|ribosomal protein S6 kinase alpha 2|ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Roux PP (2003)
    bait Zhao Y (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HIF1A
  • HIF-1alpha
  • HIF1-ALPHA
  • MOP1
  • EG3091
    		•  The BioGRID Database Seperator ARNT interacting protein|hypoxia-inducible factor 1, alpha subunit|member of PAS superfamily 1; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
    Gene Ontology: [View List]
    Invivo
    hit Richard DE (1999)
    Invitro
    hit Richard DE (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP3
  • VHR
  • EG1845
    		•  The BioGRID Database Seperator dual specificity phosphatase 3|serine/threonine specific protein phosphatase|vaccinia virus phosphatase VH1-related; dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
    Gene Ontology: [View List]
    Biochemical Activity
    bait Todd JL (1999)
    Affinity Capture-Western
    bait Todd JL (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     C1QBP
  • GC1QBP
  • HABP1
  • SF2p32
  • EG708
    		•  The BioGRID Database Seperator C1q globular domain-binding protein|hyaluronan-binding protein 1|splicing factor SF2-associated protein; complement component 1, q subcomponent binding protein
    Gene Ontology: [View List]
    Invitro
    bait Majumdar M (2002)
    Invivo
    bait Majumdar M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPIB
  • SPI-B
  • EG6689
    		•  The BioGRID Database Seperator Spi-B transcription factor (Spi-1/PU.1 related)
    Gene Ontology: [View List]
    Co-purification
    bait Mao C (1996)
    Biochemical Activity
    hit Mao C (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP1
  • CL100
  • HVH1
  • MKP-1
  • EG1843
    		•  The BioGRID Database Seperator serine/threonine specific protein phosphatase; dual specificity phosphatase 1
    Gene Ontology: [View List]
    Invivo
    hit Slack DN (2001)
    Invitro
    hit Slack DN (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNCG
  • BCSG1
  • SR
  • EG6623
    		•  The BioGRID Database Seperator breast cancer-specific protein 1|persyn|synoretin|synuclein, gamma (breast cancer-specific gene 1); synuclein, gamma (breast cancer-specific protein 1)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Pan ZZ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNCA
  • NACP
  • PARK1
  • PARK4
  • EG6622
    		•  The BioGRID Database Seperator alpha synuclein|alpha-synuclein|alpha-synuclein, isoform NACP140|non A-beta component of AD amyloid|non A4 component of amyloid; synuclein, alpha (non A4 component of amyloid precursor)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Pan ZZ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPRR
  • DKFZp781C...
  • EC-PTP
  • PCPTP1
  • EG5801
    		•  The BioGRID Database Seperator Ch-1 PTPase|protein tyrosine phosphatase Cr1PTPase|protein-tyrosine phosphatase NC-PTPCOM1; protein tyrosine phosphatase, receptor type, R
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Pulido R (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARRB2
  • ARB2
  • ARR2
  • DKFZp686L...
  • EG409
    		•  The BioGRID Database Seperator arrestin, beta 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Tohgo A (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN5
  • FLJ14427
  • PTPSTEP
  • STEP
  • EG84867
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Pulido R (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AVPR2
  • ADHR
  • DI1
  • DIR
  • EG554
    		•  The BioGRID Database Seperator arginine vasopressin receptor 2 (nephrogenic diabetes insipidus); arginine vasopressin receptor 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Tohgo A (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LYN
  • JTK8
  • FLJ26625
  • EG4067
    		•  The BioGRID Database Seperator Yamaguchi sarcoma viral (v-yes-1) oncogene homolog|Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Wei S (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IER3
  • DIF-2
  • DIF2
  • GLY96
  • DAQB-47P1...
    		•  The BioGRID Database Seperator PACAP-responsive gene 1|anti-death protein|differentiation-dependent gene 2|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediately early gene X-1|radiation-inducible immediate-early gene IEX-1; immediate early response 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Garcia J (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MKNK1
  • MNK1
  • EG8569
    		•  The BioGRID Database Seperator MAP kinase interacting kinase 1|MAP kinase-interacting serine/threonine kinase 1; MAP kinase interacting serine/threonine kinase 1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Fukunaga R (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ETV1
  • DKFZp781L...
  • ER81
  • MGC104699
  • EG2115
    		•  The BioGRID Database Seperator ets variant gene 1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Janknecht R (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP4
  • HVH2
  • MKP-2
  • MKP2
  • EG1846
    		•  The BioGRID Database Seperator MAP kinase phosphatase 2|VH1 homologous phosphatase 2|serine/threonine specific protein phosphatase; dual specificity phosphatase 4
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Chen P (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEA15
  • HMAT1
  • HUMMAT1H
  • MAT1
  • RP11-536C...
    		•  The BioGRID Database Seperator Phosphoprotein enriched in astrocytes, 15kD|homolog of mouse MAT-1 oncogene; phosphoprotein enriched in astrocytes 15
    Gene Ontology: [View List]
    Two-hybrid
    bait Formstecher E (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K1IP1
  • MP1
  • EG8649
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase 1 interacting protein 1; MEK binding partner 1|MEK partner 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Schaeffer HJ (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DCC
  • CRC18
  • CRCR1
  • EG1630
    		•  The BioGRID Database Seperator deleted in colorectal cancer protein; deleted in colorectal carcinoma
    Gene Ontology: [View List]
    Two-hybrid
    bait Forcet C (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     INSR
  • CD220
  • HHF5
  • EG3643
    		•  The BioGRID Database Seperator insulin receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Lin YL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JUN
  • AP1
  • c-Jun
  • EG3725
    		•  The BioGRID Database Seperator Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog; jun oncogene
    Gene Ontology: [View List]
    Biochemical Activity
    hit Pulverer BJ (1991)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Rps6kb1
  • 2610318I1...
  • 70kDa
  • S6K1
  • RP23-467J...
    		•  The BioGRID Database Seperator ribosomal protein S6 kinase, 70kD, polypeptide 1; ribosomal protein S6 kinase, polypeptide 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Zhang Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EDD
  • DD5
  • HYD
  • KIAA0896
  • EG51366
    		•  The BioGRID Database Seperator E3 identified by differential display|E3 ubiquitin protein ligase, HECT domain containing, 1|hyperplastic discs protein homolog|progestin induced protein|ubiquitin-protein ligase; ubiquitin protein ligase E3 component n-recognin 5
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Eblen ST (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GMFB
  • GMF
  • EG2764
    		•  The BioGRID Database Seperator glia maturation factor, beta
    Gene Ontology: [View List]
    Invivo
    hit Zaheer A (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HDAC4
  • HA6116
  • HD4
  • HDAC-A
  • EG9759
    		•  The BioGRID Database Seperator histone deacetylase 4; histone deacetylase A
    Gene Ontology: [View List]
    Invitro
    hit Zhou X (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP5
  • DUSP
  • HVH3
  • EG1847
    		•  The BioGRID Database Seperator VH1-like phosphatase 3|serine/threonine specific protein phosphatase; dual specificity phosphatase 5
    Gene Ontology: [View List]
    Invitro
    hit Kwak SP (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYLK
  • DKFZp686I...
  • FLJ12216
  • KRP
  • EG4638
    		•  The BioGRID Database Seperator myosin light chain kinase|myosin, light polypeptide kinase; myosin, light chain kinase
    Gene Ontology: [View List]
    Invitro
    hit Nguyen DH (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SREBF2
  • SREBP2
  • EG6721
    		•  The BioGRID Database Seperator OTTHUMP00000028740|sterol regulatory element-binding protein 2|sterol regulatory element-binding transcription factor 2; sterol regulatory element binding transcription factor 2
    Gene Ontology: [View List]
    Invitro
    hit Kotzka J (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TP53
  • TRP53
  • p53
  • LFS1
  • EG7157
    		•  The BioGRID Database Seperator tumor protein p53 (Li-Fraumeni syndrome); p53 tumor suppressor|tumor protein p53
    Gene Ontology: [View List]
    Invivo
    hit Persons DL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TH
  • TYH
  • EG7054
    		•  The BioGRID Database Seperator tyrosine hydroxylase
    Gene Ontology: [View List]
    Invivo
    hit Haycock JW (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELK1
  • EG2002
    		•  The BioGRID Database Seperator ELK1, member of ETS oncogene family; ELK1 protein
    Gene Ontology: [View List]
    Invivo
    bait Rao VN (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Lin YL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP6
  • MKP3
  • PYST1
  • EG1848
    		•  The BioGRID Database Seperator MAP kinase phosphatase 3|serine/threonine specific protein phosphatase; dual specificity phosphatase 6
    Gene Ontology: [View List]
    Invitro
    bait Muda M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK14
  • CSBP1
  • CSBP2
  • CSPB1
  • RP1-179N1...
    		•  The BioGRID Database Seperator Csaids binding protein|MAP kinase Mxi2|MAX-interacting protein 2|cytokine suppressive anti-inflammatory drug binding protein|p38 MAP kinase|p38 mitogen activated protein kinase|p38alpha Exip|stress-activated protein kinase 2A; mitogen-activated protein kinase 14
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sanz-Moreno V (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA4
  • MSK2
  • RSK-B
  • EG8986
    		•  The BioGRID Database Seperator mitogen- and stress-activated protein kinase 2|ribosomal protein S6 kinase alpha 4|ribosomal protein S6 kinase, 90kD, polypeptide 4|ribosomal protein kinase B; ribosomal protein S6 kinase, 90kDa, polypeptide 4
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Pierrat B (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA3
  • HU-3
  • ISPK-1
  • MAPKAPK1B
  • RP11-393H...
    		•  The BioGRID Database Seperator insulin-stimulated protein kinase 1|mental retardation, X-linked 19|ribosomal protein S6 kinase, 90kD, polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zhao Y (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K3
  • MAPKK3
  • MEK3
  • MKK3
  • EG5606
    		•  The BioGRID Database Seperator MAP kinase kinase 3|MAPK/ERK kinase 3|dual specificity mitogen activated protein kinase kinase 3; mitogen-activated protein kinase kinase 3
    Gene Ontology: [View List]
    Invitro
    hit Zheng CF (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator