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BioGRID | Network Layout for MAPK1 for Homo sapiens
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MAPK1

 Homo sapiens
The BioGRID Database Seperator
Aliases: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, EG5594
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: extracellular signal-regulated kinase 2|extracellular signal-regulated kinase-2|mitogen-activated protein kinase 2|protein tyrosine kinase ERK2; mitogen-activated protein kinase 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 7 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MAPK1

MAPK1 was identified with 109 protein interactions and 1 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MAP2K1
  • MAPKK1
  • MEK1
  • MKK1
  • EG5604
    		•  The BioGRID Database Seperator protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); mitogen-activated protein kinase kinase 1
    Gene Ontology: [View List]
    Invivo
    hit Xu Be (2001)
    hit Robinson MJ (2002)
    Invitro
    hit Xu Be (2001)
    hit Robinson MJ (2002)
    Two-hybrid
    hit Xu Be (2001)
    hit Robinson MJ (2002)
    bait Robinson FL (2002)
    Affinity Capture-Western
    hit Sanz-Moreno V (2003)
    Biochemical Activity
    bait Sanz-Moreno V (2003)
    Reconstituted Complex
    bait/hit Yeung K (2000)
    hit Wunderlich W (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MKNK2
  • GPRK7
  • MNK2
  • EG2872
    		•  The BioGRID Database Seperator G protein-coupled receptor kinase 7|MAP kinase-interacting serine/threonine kinase 2|Putative map kinase interacting kinase; MAP kinase interacting serine/threonine kinase 2
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Slentz-Kesler K (2000)
    bait Waskiewicz AJ (1997)
    Affinity Capture-Western
    bait Scheper GC (2003)
    Reconstituted Complex
    bait Waskiewicz AJ (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT5A
  • MGF
  • STAT5
  • EG6776
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 5A
    Gene Ontology: [View List]
    Invivo
    hit Dinerstein-Cali H (2000)
    Invitro
    hit Dinerstein-Cali H (2000)
    Reconstituted Complex
    bait Pircher TJ (1999)
    Affinity Capture-Western
    bait Pircher TJ (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN7
  • BPTP-4
  • HEPTP
  • LC-PTP
  • EG5778
    		•  The BioGRID Database Seperator dual specificity phosphatase 1|hematopoietic protein-tyrosine phosphatase|protein-tyrosine phoshatase, nonreceptor-type, stress induced; protein tyrosine phosphatase, non-receptor type 7
    Gene Ontology: [View List]
    Invivo
    hit Saxena M (1999)
    Invitro
    hit Saxena M (1999)
    Affinity Capture-Western
    bait Pettiford SM (2000)
    Biochemical Activity
    bait Pettiford SM (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FHL2
  • DRAL
  • SLIM3
  • AAG11
  • EG2274
    		•  The BioGRID Database Seperator aging-associated gene 11|down-regulated in rhabdomyosarcoma LIM protein|four and a half LIM-domain protein 2; four and a half LIM domains 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Purcell NH (2004)
    Reconstituted Complex
    bait/hit Purcell NH (2004)
    Affinity Capture-Western
    hit Purcell NH (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA1
  • HU-1
  • MAPKAPK1A
  • RSK
  • EG6195
    		•  The BioGRID Database Seperator dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)|p90-RSK 1|ribosomal protein S6 kinase alpha 1|ribosomal protein S6 kinase, 90kD, 1|ribosomal protein S6 kinase, 90kD, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Roux PP (2003)
    Biochemical Activity
    hit Eblen ST (2003)
    Reconstituted Complex
    bait Smith JA (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNIP1
  • ABIN-1
  • KIAA0113
  • NAF1
  • EG10318
    		•  The BioGRID Database Seperator Nef-associated factor 1 SNP|virion-associated nuclear-shuttling protein; TNFAIP3 interacting protein 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Zhang S (2002)
    Reconstituted Complex
    hit Zhang S (2002)
    Affinity Capture-Western
    hit Zhang S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEK2
  • HsPK 21
  • HsPK21
  • NEK2A
  • EG4751
    		•  The BioGRID Database Seperator NIMA (never in mitosis gene a)-related kinase 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Lou Y (2004)
    Affinity Capture-Western
    hit Lou Y (2004)
    Reconstituted Complex
    hit Lou Y (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADAM17
  • CD156b
  • MGC71942
  • TACE
  • EG6868
    		•  The BioGRID Database Seperator ADAM metallopeptidase domain 17|TNF-alpha converting enzyme|a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)|snake venom-like protease; ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Diaz-Rodriguez E (2002)
    Biochemical Activity
    hit Diaz-Rodriguez E (2002)
    Affinity Capture-Western
    bait Diaz-Rodriguez E (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELK1
  • EG2002
    		•  The BioGRID Database Seperator ELK1, member of ETS oncogene family; ELK1 protein
    Gene Ontology: [View List]
    Invitro
    bait Cano E (1995)
    bait Rao VN (1994)
    Biochemical Activity
    hit Eblen ST (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP1
  • CL100
  • HVH1
  • MKP-1
  • EG1843
    		•  The BioGRID Database Seperator serine/threonine specific protein phosphatase; dual specificity phosphatase 1
    Gene Ontology: [View List]
    Invivo
    bait Slack DN (2001)
    Invitro
    bait Slack DN (2001)
    Two-hybrid
    bait Slack DN (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TOB1
  • APRO6
  • MGC34446
  • TOB
  • EG10140
    		•  The BioGRID Database Seperator transducer of ERBB2, 1; transducer of erbB-2
    Gene Ontology: [View List]
    Invivo
    bait Maekawa M (2002)
    Invitro
    bait Maekawa M (2002)
    Two-hybrid
    bait Maekawa M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA2
  • HU-2
  • MAPKAPK1C
  • RSK
  • EG6196
    		•  The BioGRID Database Seperator ribosomal S6 kinase 3|ribosomal protein S6 kinase alpha 2|ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Roux PP (2003)
    bait Zhao Y (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK14
  • CSBP1
  • CSBP2
  • CSPB1
  • RP1-179N1...
    		•  The BioGRID Database Seperator Csaids binding protein|MAP kinase Mxi2|MAX-interacting protein 2|cytokine suppressive anti-inflammatory drug binding protein|p38 MAP kinase|p38 mitogen activated protein kinase|p38alpha Exip|stress-activated protein kinase 2A; mitogen-activated protein kinase 14
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sanz-Moreno V (2003)
    bait Tanoue T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     C1QBP
  • GC1QBP
  • HABP1
  • SF2p32
  • EG708
    		•  The BioGRID Database Seperator C1q globular domain-binding protein|hyaluronan-binding protein 1|splicing factor SF2-associated protein; complement component 1, q subcomponent binding protein
    Gene Ontology: [View List]
    Invitro
    bait Majumdar M (2002)
    Invivo
    bait Majumdar M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP22
  • JKAP
  • JSP1
  • MKPX
  • EG56940
    		•  The BioGRID Database Seperator JNK-stimulating phosphatase 1|homolog of mouse dual specificity phosphatase LMW-DSP2|mitogen-activated protein kinase phosphatase x; dual specificity phosphatase 22
    Gene Ontology: [View List]
    Biochemical Activity
    bait Aoyama K (2001)
    Affinity Capture-Western
    bait Aoyama K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA3
  • HU-3
  • ISPK-1
  • MAPKAPK1B
  • RP11-393H...
    		•  The BioGRID Database Seperator insulin-stimulated protein kinase 1|mental retardation, X-linked 19|ribosomal protein S6 kinase, 90kD, polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zhao Y (1996)
    bait Smith JA (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSC2
  • LAM
  • TSC4
  • FLJ43106
  • EG7249
    		•  The BioGRID Database Seperator tuberous sclerosis 2; tuberin
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Ma L (2005)
    Affinity Capture-Western
    hit Ma L (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EDD
  • DD5
  • HYD
  • KIAA0896
  • EG51366
    		•  The BioGRID Database Seperator E3 identified by differential display|E3 ubiquitin protein ligase, HECT domain containing, 1|hyperplastic discs protein homolog|progestin induced protein|ubiquitin-protein ligase; ubiquitin protein ligase E3 component n-recognin 5
    Gene Ontology: [View List]
    Biochemical Activity
    hit Eblen ST (2003)
    Affinity Capture-Western
    bait Eblen ST (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP3
  • VHR
  • EG1845
    		•  The BioGRID Database Seperator dual specificity phosphatase 3|serine/threonine specific protein phosphatase|vaccinia virus phosphatase VH1-related; dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
    Gene Ontology: [View List]
    Biochemical Activity
    bait Todd JL (1999)
    Affinity Capture-Western
    bait Todd JL (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV1
  • VAV
  • EG7409
    		•  The BioGRID Database Seperator oncogene vav|vav 1 oncogene|vav proto-oncogene; vav 1 guanine nucleotide exchange factor
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Song JS (1996)
    bait Lee IS (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MKNK1
  • MNK1
  • EG8569
    		•  The BioGRID Database Seperator MAP kinase interacting kinase 1|MAP kinase-interacting serine/threonine kinase 1; MAP kinase interacting serine/threonine kinase 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Waskiewicz AJ (1997)
    Two-hybrid
    bait Waskiewicz AJ (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHC1
  • FLJ26504
  • SHC
  • SHCA
  • EG6464
    		•  The BioGRID Database Seperator SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1
    Gene Ontology: [View List]
    Invivo
    hit Dinerstein-Cali H (2000)
    Invitro
    hit Dinerstein-Cali H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYC
  • c-Myc
  • EG4609
    		•  The BioGRID Database Seperator avian myelocytomatosis viral oncogene homolog|myc proto-oncogene protein|v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Jin Z (2004)
    bait Gupta S (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCAM-1
  • SORBS3
  • SH3D4
  • vinexin
  • EG10174
    		•  The BioGRID Database Seperator vinexin beta (SH3-containing adaptor molecule-1); sorbin and SH3 domain containing 3
    Gene Ontology: [View List]
    Biochemical Activity
    hit Mitsushima M (2004)
    Affinity Capture-Western
    bait Mitsushima M (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEA15
  • HMAT1
  • HUMMAT1H
  • MAT1
  • RP11-536C...
    		•  The BioGRID Database Seperator Phosphoprotein enriched in astrocytes, 15kD|homolog of mouse MAT-1 oncogene; phosphoprotein enriched in astrocytes 15
    Gene Ontology: [View List]
    Two-hybrid
    bait Formstecher E (2001)
    Reconstituted Complex
    bait Formstecher E (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K1IP1
  • MP1
  • EG8649
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase 1 interacting protein 1; MEK binding partner 1|MEK partner 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Wunderlich W (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNCA
  • NACP
  • PARK1
  • PARK4
  • EG6622
    		•  The BioGRID Database Seperator alpha synuclein|alpha-synuclein|alpha-synuclein, isoform NACP140|non A-beta component of AD amyloid|non A4 component of amyloid; synuclein, alpha (non A4 component of amyloid precursor)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Pan ZZ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GATA4
  • MGC126629
  • EG2626
    		•  The BioGRID Database Seperator GATA binding protein 4; GATA-binding protein 4
    Gene Ontology: [View List]
    Biochemical Activity
    hit Liang Q (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Rps6kb1
  • 2610318I1...
  • 70kDa
  • S6K1
  • RP23-467J...
    		•  The BioGRID Database Seperator ribosomal protein S6 kinase, 70kD, polypeptide 1; ribosomal protein S6 kinase, polypeptide 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Zhang Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IER3
  • DIF-2
  • DIF2
  • GLY96
  • DAQB-47P1...
    		•  The BioGRID Database Seperator PACAP-responsive gene 1|anti-death protein|differentiation-dependent gene 2|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediately early gene X-1|radiation-inducible immediate-early gene IEX-1; immediate early response 3
    Gene Ontology: [View List]
    Biochemical Activity
    hit Garcia J (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HMMR
  • IHABP
  • RHAMM
  • MGC119494
  • EG3161
    		•  The BioGRID Database Seperator hyaluronan-mediated motility receptor|intracellular hyaluronic acid binding protein; hyaluronan-mediated motility receptor (RHAMM)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Lynn BD (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATF2
  • CRE-BP1
  • CREB2
  • HB16
  • EG1386
    		•  The BioGRID Database Seperator activating transcription factor 2 splice variant ATF2-var2|cAMP responsive element binding protein 2, formerly; activating transcription factor 2
    Gene Ontology: [View List]