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[JPG]
[PNG]
[SVG]
PRG1
Homo sapiens
Aliases:
FLJ12930, MGC9289, PPG, PRG, SRGN, EG5552
Description:
hematopoetic proteoglycan core peptide|platelet proteoglycan protein core|proteoglycan 1, secretory granule|proteoglycan protein core for mast cell secretory granule|secretory granule proteoglycan 1|secretory granule proteoglycan core peptide|serglycin proteoglycan; serglycin
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
12 total GO mappings for this record.
[view list]
Function
Process
Component
•
protein binding
(
ISS
)
•
T cell secretory granule ...
(
ISS
)
•
mast cell secretory granu ...
(
ISS
)
•
protein maturation via pr ...
(
ISS
)
•
negative regulation of cy ...
(
ISS
)
•
maintenance of granzyme B ...
(
ISS
)
•
negative regulation of bo ...
(
IDA
)
•
apoptosis
(
IDA
)
•
maintenance of protease l ...
(
ISS
)
•
Golgi apparatus
(
IDA
)
•
mast cell granule
(
ISS
)
•
extracellular space
(
IDA
)
Download interactions associated with PRG1
PRG1 was identified with
10
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
GZMB
CCPI
CGL-1
CGL1
EG3002
T-cell serine protease 1-3E|cathepsin G-like 1|cytotoxic serine protease B|fragmentin 2|granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Gene Ontology:
[View List]
Invitro
bait
Galvin JP (1999)
bait
Raja SM (2002)
Affinity Capture-MS
bait/hit
Rual JF (2005)
CD44
CDW44
ECMR-III
IN
EG960
CD44 antigen|CD44 antigen (Indian blood group)|CD44 antigen (homing function and Indian blood group system)|CD44 epithelial domain (CD44E)|CDW44 antigen|GP90 lymphocyte homing/adhesion receptor|Hermes antigen|antigen gp90 homing receptor|cell adhesion molecule (CD44)|cell surface glycoprotein...
Gene Ontology:
[View List]
Invivo
bait
Toyama-Sorimachi N (1997)
Affinity Capture-MS
bait
Rual JF (2005)
PF4
CXCL4
SCYB4
MGC138298
EG5196
platelet factor 4 (chemokine (C-X-C motif) ligand 4)
Gene Ontology:
[View List]
Invivo
hit
Kolset SO (1996)
Invitro
hit
Kolset SO (1996)
SGTA
SGT
hSGT
EG6449
protein containing three tetratricopeptide repeats|small glutamine-rich tetratricopeptide; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
Gene Ontology:
[View List]
Two-hybrid
hit
Rual JF (2005)
CCL3
G0S19-1
LD78ALPHA
MIP-1-alpha
EG6348
LD78 alpha beta|small inducible cytokine A3 (homologous to mouse Mip-1a); chemokine (C-C motif) ligand 3
Gene Ontology:
[View List]
Invivo
hit
Kolset SO (1996)
ALB
DKFZp779N...
PRO0883
PRO1341
EG213
cell growth inhibiting protein 42|growth-inhibiting protein 20|serum albumin; albumin
Gene Ontology:
[View List]
Invitro
bait
Hatton MN (1985)
Copyright © 2007,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.