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PPP2R4
Homo sapiens
Aliases:
MGC2184, PP2A, PR53, PTPA, RP11-247A12.4
Description:
PP2A phosphatase activator|PP2A, subunit B'|phosphotyrosyl phosphatase activator|protein phosphatase 2A, regulatory subunit B'|protein phosphatase 2A, regulatory subunit B' (PR 53); protein phosphatase 2A activator, regulatory subunit 4
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
14 total GO annotations for this record.
[view list]
Function
Process
Component
•
protein phosphatase 2A bi ...
(
IDA
)
•
ATP binding
(
IDA
)
•
protein heterodimerizatio ...
(
TAS
)
•
protein tyrosine phosphat ...
(
IDA
)
•
protein phosphatase type ...
(
TAS
)
•
protein homodimerization ...
(
IDA
)
•
ATPase activity
(
IDA
)
•
positive regulation of ph ...
(
IDA
)
•
negative regulation of pr ...
(
IDA
)
•
negative regulation of ph ...
(
IDA
)
•
positive regulation of pr ...
(
IDA
)
•
protein amino acid dephos ...
(
NAS
)
•
soluble fraction
(
TAS
)
•
protein phosphatase type ...
(
TAS
)
Download interactions associated with PPP2R4
PPP2R4 was identified with
6
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
CCNG1
CCNG
EG900
cyclin G1
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Okamoto K (1996)
Two-hybrid
hit
Okamoto K (1996)
STRN3
SG2NA
EG29966
cell cycle S/G2 nuclear autoantigen|nuclear autoantigen; striatin, calmodulin binding protein 3
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Moreno CS (2000)
JAK2
EG3717
Janus kinase 2|OTTHUMP00000043260|tyrosine-protein kinase JAK2; Janus kinase 2 (a protein tyrosine kinase)
Gene Ontology:
[View List]
Affinity Capture-Western
bait/hit
Fuhrer DK (1996)
BCL2
Bcl-2
EG596
B-cell lymphoma protein 2; B-cell CLL/lymphoma 2
Gene Ontology:
[View List]
Biochemical Activity
hit
Tamura Y (2004)
RRD2
YPA2
YPL152W
Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex|Rrd2p; protein coding
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Fellner T (2003)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.