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PPARD
Homo sapiens
Aliases:
FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPAR-beta, PPARB, EG5467
Description:
nuclear hormone receptor 1|peroxisome proliferative activated receptor, delta; peroxisome proliferator-activated receptor delta
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
27 total GO annotations for this record.
[view list]
Function
Process
Component
•
retinoid X receptor bindi ...
(
ISS
)
•
steroid hormone receptor ...
(
TAS
)
•
transcription factor acti ...
(
NAS
)
•
fatty acid binding
(
NAS
)
•
prostacyclin receptor act ...
(
ISS
)
•
transcription repressor a ...
(
ISS
)
•
protein heterodimerizatio ...
(
ISS
)
•
enzyme activator activity
(
ISS
)
•
apoptosis
(
IMP
)
•
glucose transport
(
NAS
)
•
positive regulation of fa ...
(
NAS
)
•
embryo implantation
(
TAS
)
•
epidermis development
(
ISS
)
•
glucose metabolic process
(
NAS
)
•
cell proliferation
(
TAS
)
•
regulation of transcripti ...
(
TAS
)
•
negative regulation of tr ...
(
ISS
)
•
generation of precursor m ...
(
TAS
)
•
fatty acid transport
(
ISS
)
•
decidualization
(
TAS
)
•
regulation of insulin sec ...
(
ISS
)
•
fatty acid catabolic proc ...
(
TAS
)
•
fatty acid beta-oxidation
(
TAS
)
•
axon ensheathment
(
ISS
)
•
lipid metabolic process
(
ISS
)
•
cholesterol metabolic pro ...
(
TAS
)
•
nucleus
(
NAS
)
Download interactions associated with PPARD
PPARD was identified with
13
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
NCOR2
CTG26
SMRT
SMRTE
EG9612
silencing mediator for retinoid and thyroid hormone receptors; nuclear receptor co-repressor 2
Gene Ontology:
[View List]
Two-hybrid
hit
Shi Y (2002)
Affinity Capture-Western
bait
Shi Y (2002)
HDAC3
HD3
RPD3
RPD3-2
EG8841
histone deacetylase 3
Gene Ontology:
[View List]
Reconstituted Complex
hit
Franco PJ (2003)
Affinity Capture-Western
hit
Shi Y (2002)
GADD45G
CR6
DDIT2
GADD45gamma
EG10912
GADD45-gamma|gadd-related protein, 17 kD|growth arrest and DNA-damage-inducible gamma; growth arrest and DNA-damage-inducible, gamma
Gene Ontology:
[View List]
Invitro
bait
Yi YW (2000)
Reconstituted Complex
bait
Yi YW (2000)
HDAC1
HD1
RPD3
RPD3L1
EG3065
reduced potassium dependency, yeast homolog-like 1; histone deacetylase 1
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Shi Y (2002)
HDAC2
RPD3
YAF1
EG3066
OTTHUMP00000040427|YY1-associated factor 1|transcriptional regulator homolog RPD3; histone deacetylase 2
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Shi Y (2002)
SPEN
KIAA0929
MINT
SHARP
EG23013
Msx2 interacting nuclear target (MINT) homolog|OTTHUMP00000044600|SMART/HDAC1 associated repressor protein|nuclear receptor transcription cofactor|spen homolog, transcriptional regulator; spen homolog, transcriptional regulator (Drosophila)
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Shi Y (2002)
NCOR1
KIAA1047
N-CoR
TRAC1
EG9611
thyroid hormone- and retinoic acid receptor-associated corepressor 1; nuclear receptor co-repressor 1
Gene Ontology:
[View List]
Two-hybrid
hit
Shi Y (2002)
GADD45B
DKFZP566B...
GADD45BETA
MYD118
EG4616
growth arrest and DNA-damage-inducible beta|myeloid differentiation primary response; growth arrest and DNA-damage-inducible, beta
Gene Ontology:
[View List]
Invitro
bait
Yi YW (2000)
Gadd45b
Myd118
AI323528
EG17873
myeloid differentiation primary response gene 118; growth arrest and DNA-damage-inducible 45 beta
Gene Ontology:
[View List]
Reconstituted Complex
bait
Yi YW (2000)
HDAC4
HA6116
HD4
HDAC-A
EG9759
histone deacetylase 4; histone deacetylase A
Gene Ontology:
[View List]
Reconstituted Complex
hit
Franco PJ (2003)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.