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POMC
Homo sapiens
Aliases:
ACTH, CLIP, MSH, POC, LPH, NPP, EG5443
Description:
adrenocorticotropic hormone|adrenocorticotropin|alpha-MSH|alpha-melanocyte-stimulating hormone|beta-LPH|beta-MSH|beta-endorphin|beta-melanocyte-stimulating hormone|corticotropin|corticotropin-like intermediary peptide|corticotropin-lipotrophin|gamma-LPH|gamma-MSH|lipotropin beta|lipotropin gamma|melanotropin alpha|melanotropin beta|melanotropin gamma|met-enkephalin|pro-ACTH-endorphin|pro-opiomelanocortin|proopiomelanocortin|proopiomelanocortin preproprotein; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
5 total GO annotations for this record.
[view list]
Function
Process
Component
•
hormone activity
(
TAS
)
•
signal transduction
(
TAS
)
•
cell-cell signaling
(
TAS
)
•
generation of precursor m ...
(
TAS
)
•
soluble fraction
(
TAS
)
Download interactions associated with POMC
POMC was identified with
5
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
MC4R
MGC126851
MGC138197
EG4160
melanocortin 4 receptor
Gene Ontology:
[View List]
Invivo
hit
Yang YK (2000)
Invitro
hit
Yang YK (2000)
VTN
V75
VNT
VN
EG7448
complement S-protein|epibolin|serum spreading factor|somatomedin B|vitronectin (serum spreading factor, somatomedin B, complement S-protein); vitronectin
Gene Ontology:
[View List]
Reconstituted Complex
bait
Hildebrand A (1989)
MC1R
MGC14337
MSH-R
EG4157
melanocortin 1 receptor|melanocyte stimulating hormone receptor|melanotropin receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
Gene Ontology:
[View List]
Invivo
hit
Abdel-Malek Z (2000)
HLA-DRB3
HLA-DR3B
MGC117330
EG3125
MHC class II HLA-DR beta 3 chain|MHC class II antigen DR beta 3 chain|human leucocyte antigen DRB3; major histocompatibility complex, class II, DR beta 3
Gene Ontology:
[View List]
Co-crystal Structure
bait
Ghosh P (1995)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.