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BioGRID | Network Layout for PLCG1 for Homo sapiens
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PLCG1

 Homo sapiens
The BioGRID Database Seperator
Aliases: PLC-II, PLC1, PLC148, PLCgamma1, EG5335
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phospholipase C|phospholipase C gamma 1|phospholipase C, gamma 1 (formerly subtype 148)|phospholipase C-148|triphosphoinositide phosphodiesterase; phospholipase C, gamma 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with PLCG1

PLCG1 was identified with 99 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 KHDRBS1
  • Sam68
  • p62
  • FLJ34027
  • EG10657
    		•  The BioGRID Database Seperator KH domain containing, RNA binding, signal transduction associated 1; GAP-associated tyrosine phosphoprotein p62 (Sam68)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Oneyama C (2002)
    hit Jabado N (1998)
    bait Shen Z (1999)
    Reconstituted Complex
    bait Shen Z (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EEF1A1
  • EEF-1
  • EEF1A
  • EF-Tu
  • RP11-505P...
    		•  The BioGRID Database Seperator CTCL tumor antigen|EF1a-like protein|cervical cancer suppressor 3|elongation factor 1 alpha subunit|elongation factor 1-alpha|elongation factor Tu|eukaryotic translation elongation factor 1 alpha 1-like 14|glucocorticoid receptor AF-1 specific elongation factor|leukocyte receptor cluster (LRC)...
    Gene Ontology: [View List]
    Two-hybrid
    hit Chang JS (2002)
    Reconstituted Complex
    hit Chang JS (2002)
    Far Western
    hit Chang JS (2002)
    Affinity Capture-Western
    bait/hit Chang JS (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBL
  • C-CBL
  • CBL2
  • RNF55
  • EG867
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence; oncogene CBL2
    Gene Ontology: [View List]
    Far Western
    bait Tvorogov D (2002)
    Reconstituted Complex
    hit Tvorogov D (2002)
    hit Graham LJ (1998)
    Affinity Capture-Western
    hit Tvorogov D (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAB1
  • EG2549
    		•  The BioGRID Database Seperator GRB2-associated binding protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Ueno E (2001)
    bait Holgado-Madruga M (1996)
    Far Western
    bait Holgado-Madruga M (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Pei Z (1997)
    bait Nel AE (1995)
    Reconstituted Complex
    hit Pei Z (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ITK
  • EMT
  • LYK
  • PSCTK2
  • EG3702
    		•  The BioGRID Database Seperator homolog of mouse T-cell itk/tsk|tyrosine-protein kinase ITK/TSK|tyrosine-protein kinase LYK; IL2-inducible T-cell kinase
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Perez-Villar JJ (1999)
    Affinity Capture-Western
    bait Perez-Villar JJ (1999)
    Biochemical Activity
    bait/hit Hao S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NTRK1
  • MTC
  • TRK
  • TRK1
  • EG4914
    		•  The BioGRID Database Seperator Oncogene TRK|high affinity nerve growth factor receptor|tyrosine kinase receptor A; neurotrophic tyrosine kinase, receptor, type 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Ohmichi M (1991)
    hit Meakin SO (1999)
    Two-hybrid
    bait Qian X (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LAT
  • LAT1
  • pp36
  • EG27040
    		•  The BioGRID Database Seperator 36 kDa phospho-tyrosine adaptor protein; linker for activation of T cells
    Gene Ontology: [View List]
    Co-fractionation
    hit Zhang W (1998)
    Affinity Capture-Western
    bait Paz PE (2001)
    Reconstituted Complex
    bait Paz PE (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTSS
  • MGC3886
  • EG1520
    		•  The BioGRID Database Seperator cathepsin S
    Gene Ontology: [View List]
    Invivo
    hit Baldassare JJ (1997)
    Invitro
    hit Baldassare JJ (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIT
  • C-Kit
  • CD117
  • PBT
  • EG3815
    		•  The BioGRID Database Seperator mast/stem cell growth factor receptor|proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Reconstituted Complex
    bait van Dijk TB (2000)
    hit Jhun BH (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH3BP2
  • CRBM
  • CRPM
  • RES4-23
  • EG6452
    		•  The BioGRID Database Seperator SH3-domain binding protein 2
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Deckert M (1998)
    Far Western
    hit Jevremovic D (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCP2
  • SLP-76
  • SLP76
  • EG3937
    		•  The BioGRID Database Seperator 76 kDa tyrosine phosphoprotein|SH2 domain-containing leukocyte protein of 76kD|lymphocyte cytosolic protein 2|lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yablonski D (2001)
    Reconstituted Complex
    hit Yablonski D (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FLT1
  • FLT
  • VEGFR1
  • EG2321
    		•  The BioGRID Database Seperator fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Cunningham SA (1997)
    Two-hybrid
    bait Cunningham SA (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERBB2
  • HER-2
  • HER-2/neu
  • HER2
  • EG2064
    		•  The BioGRID Database Seperator c-erb B2/neu protein|erbB-2|herstatin|neuroblastoma/glioblastoma derived oncogene homolog|v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Peles E (1991)
    Co-fractionation
    hit Arteaga CL (1991)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Invivo
    hit Bedrin MS (1997)
    Affinity Capture-Western
    bait Tvorogov D (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDGFRA
  • CD140A
  • MGC74795
  • PDGFR2
  • EG5156
    		•  The BioGRID Database Seperator FIP1L1/PDGFRA fusion protein|platelet-derived growth factor receptor alpha|rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; platelet-derived growth factor receptor, alpha polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Eriksson A (1995)
    Reconstituted Complex
    hit Eriksson A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHOA
  • ARH12
  • ARHA
  • RHO12
  • EG387
    		•  The BioGRID Database Seperator Aplysia ras-related homolog 12|oncogene RHO H12|small GTP binding protein RhoA; ras homolog gene family, member A
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Thodeti CK (2002)
    Reconstituted Complex
    bait Thodeti CK (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PITPNA
  • MGC99649
  • PITPN
  • VIB1A
  • EG5306
    		•  The BioGRID Database Seperator phosphatidylinositol transfer protein, alpha; phosphotidylinositol transfer protein
    Gene Ontology: [View List]
    Invivo
    hit Kauffmann-Zeh A (1995)
    Invitro
    hit Kauffmann-Zeh A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOS2
  • FLJ25596
  • EG6655
    		•  The BioGRID Database Seperator guanine nucleotide exchange factor|guanine nucleotide releasing factor|son of sevenless homolog 2; son of sevenless homolog 2 (Drosophila)
    Gene Ontology: [View List]
    Invivo
    hit Scholler JK (2000)
    Two-hybrid
    hit Scholler JK (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOS1
  • GF1
  • GGF1
  • GINGF
  • EG6654
    		•  The BioGRID Database Seperator gingival fibromatosis, hereditary, 1|son of sevenless homolog 1; son of sevenless homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Kim MJ (2000)
    Affinity Capture-Western
    bait/hit Kim MJ (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TUB
  • rd5
  • EG7275
    		•  The BioGRID Database Seperator tubby homolog (mouse); tubby|tubby homologue
    Gene Ontology: [View List]
    Invivo
    hit Kapeller R (1999)
    Invitro
    hit Kapeller R (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIT1
  • EG28964
    		•  The BioGRID Database Seperator G protein-coupled receptor kinase interactor 1; G protein-coupled receptor kinase-interactor 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Haendeler J (2003)
    Reconstituted Complex
    hit Haendeler J (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PECAM1
  • CD31
  • PECAM-1
  • EG5175
    		•  The BioGRID Database Seperator platelet/endothelial cell adhesion molecule (CD31 antigen); CD31/EndoCAM|PECAM-1, CD31/EndoCAM|adhesion molecule
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Pumphrey NJ (1999)
    Far Western
    bait Pumphrey NJ (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLD2
  • EG5338
    		•  The BioGRID Database Seperator phospholipase D2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Jang IH (2003)
    Reconstituted Complex
    hit Jang IH (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAG3
  • BAG-3
  • BIS
  • CAIR-1
  • EG9531
    		•  The BioGRID Database Seperator BAG-family molecular chaperone regulator-3|BCL2-binding athanogene 3|Bcl-2-binding protein|docking protein CAIR-1; BCL2-associated athanogene 3
    Gene Ontology: [View List]
    Invivo
    hit Doong H (2000)
    Invitro
    hit Doong H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WAS
  • IMD2
  • THC
  • WASP
  • EG7454
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome protein|thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Banin S (1996)
    hit Finan PM (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZAP70
  • SRK
  • STD
  • TZK
  • EG7535
    		•  The BioGRID Database Seperator syk-related tyrosine kinase|zeta-chain (TCR) associated protein kinase (70 kD)|zeta-chain associated protein kinase 70kDa|zeta-chain associated protein kinase, 70kD; zeta-chain (TCR) associated protein kinase 70kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nel AE (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LAT2
  • HSPC046
  • LAB
  • NTAL
  • EG7462
    		•  The BioGRID Database Seperator Williams-Beuren syndrome chromosome region 15|Williams-Beuren syndrome chromosome region 5|linker for activation of B cells|linker for activation of T cells family member 2|non-T cell activation linker; linker for activation of T cells family, member 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Janssen E (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NTRK3
  • TRKC
  • gp145(trkC)
  • EG4916
    		•  The BioGRID Database Seperator ETS related protein-neurotrophic receptor tyrosine kinase fusion protein|ETV6-NTRK3 fusion|NT-3 growth factor receptor|neurotrophin 3 receptor|tyrosine kinase receptor C; neurotrophic tyrosine kinase, receptor, type 3
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Meakin SO (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LNK
  • SH2B3
  • EG10019
    		•  The BioGRID Database Seperator lymphocyte adaptor protein; SH2B adaptor protein 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Motto DG (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NTRK2
  • GP145-TrkB
  • TRKB
  • EG4915
    		•  The BioGRID Database Seperator BDNF/NT-3 growth factors receptor|tyrosine kinase receptor B; neurotrophic tyrosine kinase, receptor, type 2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Meakin SO (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RICS
  • GC-GAP
  • GRIT
  • KIAA0712
  • EG9743
    		•  The BioGRID Database Seperator GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein; Rho GTPase-activating protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Moon SY (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNK1
  • MGC46193
  • EG8711
    		•  The BioGRID Database Seperator tyrosine kinase, non-receptor, 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Felschow DM (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPRJ
  • CD148
  • DEP1
  • HPTPeta
  • EG5795
    		•  The BioGRID Database Seperator CD148 antigen|human density enhanced phosphatase-1|protein tyrosine phosphatase, receptor type, J polypeptide|receptor-type tyrosine-protein phosphatase eta|susceptibility to colon cancer 1, mouse, homolog of; protein tyrosine phosphatase, receptor type, J
    Gene Ontology: [View List]
    Biochemical Activity
    bait Baker JE (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GNB2L1
  • Gnb2-rs1
  • H12.3
  • HLC-7
  • EG10399
    		•  The BioGRID Database Seperator lung cancer oncogene 7|proliferation-inducing gene 21|protein homologous to chicken B complex protein, guanine nucleotide binding; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
    Gene Ontology: [View List]
    Far Western
    bait Disatnik MH (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS2
  • EG8660
    		•  The BioGRID Database Seperator insulin receptor substrate 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Sozzani P (1998)