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BioGRID | Network Layout for PIK3CA for Homo sapiens
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PIK3CA

 Homo sapiens
The BioGRID Database Seperator
Aliases: PI3K, p110-alpha, MGC142161, MGC142163, EG5290
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: PI3-kinase p110 subunit alpha|PtdIns-3-kinase p110|phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha|phosphatidylinositol 3-kinase, catalytic, alpha polypeptide|phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform; phosphoinositide-3-kinase, catalytic, alpha polypeptide
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 2 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with PIK3CA

PIK3CA was identified with 32 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 LCK
  • YT16
  • p56lck
  • pp58lck
  • EG3932
    		•  The BioGRID Database Seperator T-lymphocyte specific protein tyrosine kinase p56lck|p56(LSTRA) protein-tyrosine kinase|protein tyrosine kinase|proto-oncogene tyrosine-protein kinase LCK; lymphocyte-specific protein tyrosine kinase
    Gene Ontology: [View List]
    Invitro
    hit von Willebrand M (1994)
    Affinity Capture-Western
    bait Sade H (2004)
    Reconstituted Complex
    bait Prasad KV (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HRAS
  • HRAS1
  • K-ras
  • N-ras
  • EG3265
    		•  The BioGRID Database Seperator H-RasIDX|c-has/bas p21 protein|c-ras-Ki-2 protein|p21 protein; v-Ha-ras Harvey rat sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Invivo
    hit Rodriguez-Viciana P (1997)
    Reconstituted Complex
    hit Vargiu P (2004)
    Two-hybrid
    bait Li W (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH3KBP1
  • CIN85
  • MIG18
  • GIG10
  • RP11-345L...
    		•  The BioGRID Database Seperator OTTHUMP00000061480|c-Cbl-interacting protein|migration-inducing gene 18 protein; SH3-domain kinase binding protein 1
    Gene Ontology: [View List]
    Invivo
    bait Gout I (2000)
    Invitro
    bait Gout I (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NRAS
  • N-ras
  • NRAS1
  • EG4893
    		•  The BioGRID Database Seperator N-ras protein part 4|v-ras neuroblastoma RAS viral oncogene homolog; neuroblastoma RAS viral (v-ras) oncogene homolog
    Gene Ontology: [View List]
    Invivo
    bait Rodriguez-Viciana P (1996)
    Invitro
    bait Rodriguez-Viciana P (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DGKZ
  • DAGK5
  • DAGK6
  • DGK-ZETA
  • EG8525
    		•  The BioGRID Database Seperator diacylglycerol kinase, zeta (104kD); diacylglycerol kinase, zeta 104kDa
    Gene Ontology: [View List]
    Biochemical Activity
    hit Luo B (2003)
    Affinity Capture-Western
    bait Luo B (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CENTA1
  • GCS1L
  • p42IP4
  • EG11033
    		•  The BioGRID Database Seperator centaurin, alpha 1; centaurin-alpha
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Zemlickova E (2003)
    Biochemical Activity
    hit Zemlickova E (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GNAQ
  • G-ALPHA-q
  • GAQ
  • RP11-494N...
    		•  The BioGRID Database Seperator guanine nucleotide binding protein (G protein), q polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ballou LM (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF1
  • GEF1
  • LBCL2
  • P115-RHOGEF
  • EG9138
    		•  The BioGRID Database Seperator 115-kD protein|Lsc homolog|Rho guanine nucleotide exchange factor 1; Rho guanine nucleotide exchange factor (GEF) 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Holinstat M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRAS
  • C-K-RAS
  • K-RAS2A
  • K-RAS2B
  • EG3845
    		•  The BioGRID Database Seperator K-ras p21 protein|Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog|PR310 c-K-ras oncogene|c-K-ras2 protein|c-Kirsten-ras protein|cellular c-Ki-ras2 proto-oncogene|oncogene KRAS2|transforming protein p21|v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma...
    Gene Ontology: [View List]
    Two-hybrid
    bait Li W (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSN
  • DKFZp313L...
  • RP11-477J...
    		•  The BioGRID Database Seperator gelsolin (amyloidosis, Finnish type); gelsolin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chellaiah MA (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS4
  • IRS-4
  • PY160
  • EG8471
    		•  The BioGRID Database Seperator insulin receptor substrate 4
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Sano H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAH
  • YWHA1
  • EG7533
    		•  The BioGRID Database Seperator tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; 14-3-3 eta|tyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ichimura T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS1
  • HIRS-1
  • EG3667
    		•  The BioGRID Database Seperator insulin receptor substrate 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Tzatsos A (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R1
  • GRB1
  • p85-ALPHA
  • EG5295
    		•  The BioGRID Database Seperator phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit, polypeptide 1|phosphoinositide-3-kinase, regulatory subunit, polypeptide...
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Woscholski R (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOTCH1
  • TAN1
  • hN1
  • EG4851
    		•  The BioGRID Database Seperator neurogenic locus notch homolog protein 1|notch1|translocation-associated notch protein TAN-1; Notch homolog 1, translocation-associated (Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sade H (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBL
  • C-CBL
  • CBL2
  • RNF55
  • EG867
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence; oncogene CBL2
    Gene Ontology: [View List]
    Co-purification
    bait Salgia R (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCD
  • MAY1
  • MGC49908
  • nPKC-delta
  • EG5580
    		•  The BioGRID Database Seperator protein kinase C, delta
    Gene Ontology: [View List]
    Invitro
    bait Stetak A (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R3
  • DKFZp686P...
  • p55-GAMMA
  • FLJ41892
  • EG8503
    		•  The BioGRID Database Seperator 100% homology to SWISS-PROT Q92569|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)
    Gene Ontology: [View List]
    Two-hybrid
    bait Mothe I (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATR
  • FRP1
  • SCKL
  • SCKL1
  • EG545
    		•  The BioGRID Database Seperator FRAP-related protein-1|MEC1, mitosis entry checkpoint 1, homolog|Rad3 related protein|Seckel syndrome|ataxia telangiectasia and Rad3 related protein|protein kinase ATR; ataxia telangiectasia and Rad3 related
    Gene Ontology: [View List]
    Protein-peptide
    bait/hit Kim ST (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAQ
  • 1C5
  • HS1
  • 14-3-3
  • EG10971
    		•  The BioGRID Database Seperator 14-3-3 protein T-cell|14-3-3 protein tau|14-3-3 protein theta|protein tau|tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Liu YC (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLC9A3R2
  • E3KARP
  • NHE3RF2
  • NHERF-2
  • EG9351
    		•  The BioGRID Database Seperator sodium/hydrogen exchanger|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2|solute carrier family 9 isoform 3 regulator 2; solute carrier family 9 (sodium/hydrogen exchanger), member...
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Lee-Kwon W (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RASD2
  • MGC:4834
  • Rhes
  • TEM2
  • EG23551
    		•  The BioGRID Database Seperator GTP-binding protein Rhes|Ras homolog enriched in striatum|tumor endothelial marker 2; RASD family, member 2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Vargiu P (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RASGRP3
  • GRP3
  • KIAA0846
  • EG25780
    		•  The BioGRID Database Seperator RAS guanyl releasing protein 3 (calcium and DAG-regulated); guanine nucleotide exchange factor for Rap1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Brodie C (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLC9A3R1
  • EBP50
  • NHERF
  • NHERF1
  • EG9368
    		•  The BioGRID Database Seperator solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Lee-Kwon W (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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