Search
Organism:
All Organisms
Arabidopsis thaliana
Bacillus subtilis 168
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Equus caballus
Escherichia coli K12
Gallus gallus
Homo sapiens
Macaca mulatta
Mus musculus
Nematostella vectensis
Oryza sativa
Pan troglodytes
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Strongylocentrotus purpuratus
Takifugu rubripes
Xenopus laevis
home
support
contribute
downloads
mirrors
about us
[JPG]
[PNG]
[SVG]
PF4
Homo sapiens
Aliases:
CXCL4, SCYB4, MGC138298, EG5196
Description:
platelet factor 4 (chemokine (C-X-C motif) ligand 4)
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
8 total GO mappings for this record.
[view list]
Function
Process
Component
•
heparin binding
(
IDA
)
•
chemokine activity
(
TAS
)
•
cytokine and chemokine me ...
(
IDA
)
•
leukocyte chemotaxis
(
IDA
)
•
negative regulation of an ...
(
IDA
)
•
platelet activation
(
IDA
)
•
negative regulation of me ...
(
IDA
)
•
extracellular region
(
NAS
)
Download interactions associated with PF4
PF4 was identified with
12
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
PF4
CXCL4
SCYB4
MGC138298
EG5196
platelet factor 4 (chemokine (C-X-C motif) ligand 4)
Gene Ontology:
[View List]
Invitro
hit
Barker S (1995)
hit
Mayo KH (1995)
Co-crystal Structure
hit
Zhang X (1994)
FGF2
BFGF
FGFB
HBGF-2
EG2247
basic fibroblast growth factor bFGF|fibroblast growth factor 2|heparin-binding growth factor 2|prostatropin; fibroblast growth factor 2 (basic)
Gene Ontology:
[View List]
Invivo
hit
Perollet C (1998)
Invitro
hit
Perollet C (1998)
PRG1
FLJ12930
MGC9289
PPG
EG5552
hematopoetic proteoglycan core peptide|platelet proteoglycan protein core|proteoglycan 1, secretory granule|proteoglycan protein core for mast cell secretory granule|secretory granule proteoglycan 1|secretory granule proteoglycan core peptide|serglycin proteoglycan; serglycin
Gene Ontology:
[View List]
Invivo
bait
Kolset SO (1996)
Invitro
bait
Kolset SO (1996)
LDLR
FH
FHC
EG3949
low density lipoprotein receptor (familial hypercholesterolemia); LDL receptor|low density lipoprotein receptor
Gene Ontology:
[View List]
Reconstituted Complex
hit
Sachais BS (2002)
PROC
PROC1
EG5624
protein C (inactivator of coagulation factors Va and VIIIa)
Gene Ontology:
[View List]
Reconstituted Complex
hit
Dudek AZ (1997)
CXCR3
CD183
CKR-L2
CMKAR3
EG2833
G protein-coupled receptor 9|IP10 receptor|Mig receptor|chemokine (C-X-C) receptor 3; chemokine (C-X-C motif) receptor 3
Gene Ontology:
[View List]
Reconstituted Complex
bait
Lasagni L (2003)
SDC2
HSPG
HSPG1
SYND2
EG6383
cell surface-associated heparan sulfate proteoglycan 1|fibroglycan|heparan sulfate proteoglycan 1, cell surface-associated|heparan sulfate proteoglycan core protein|syndecan proteoglycan 2; syndecan 2
Gene Ontology:
[View List]
Invitro
bait
Brown KJ (1994)
THBD
CD141
THRM
TM
EG7056
CD141 antigen|fetomodulin; thrombomodulin
Gene Ontology:
[View List]
Reconstituted Complex
hit
Dudek AZ (1997)
Copyright © 2007,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
terms and conditions
-
privacy policy
-
Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.