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BioGRID | Network Layout for PAK1 for Homo sapiens
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PAK1

 Homo sapiens
The BioGRID Database Seperator
Aliases: PAKalpha, MGC130000, MGC130001, EG5058
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: p21-activated kinase 1|p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 11 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with PAK1

PAK1 was identified with 44 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 DNCL1
  • DLC1
  • DLC8
  • LC8
  • EG8655
    		•  The BioGRID Database Seperator 8 kDa dynein light chain|cytoplasmic dynein light polypeptide|dynein light chain 1|dynein, cytoplasmic, light polypeptide 1|protein inhibitor of neuronal nitric oxide synthase; dynein, light chain, LC8-type 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Vadlamudi RK (2004)
    Reconstituted Complex
    bait/hit Vadlamudi RK (2004)
    Affinity Capture-Western
    bait/hit Vadlamudi RK (2004)
    Biochemical Activity
    hit Vadlamudi RK (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC2L2
  • CDC2L3
  • CDK11-p110
  • CDK11-p46
  • hCG_201158
    		•  The BioGRID Database Seperator PITSLRE B|PITSLRE protein kinase beta|PITSLRE serine/threonine-protein kinase CDC2L2|cell division cycle 2-like 2|cell division cycle 2-like protein kinase 2|galactosyltransferase-associated protein kinase p58/GTA; cell division cycle 2-like 2 (PITSLRE proteins)
    Gene Ontology: [View List]
    Two-hybrid
    hit Chen S (2003)
    Reconstituted Complex
    bait Chen S (2003)
    Affinity Capture-Western
    bait Chen S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK1IP1
  • FLJ20624
  • PIP1
  • bA421M1.5
  • EG55003
    		•  The BioGRID Database Seperator PAK/PLC-interacting protein 1|PAK1-interacting protein; PAK1 interacting protein 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Xia C (2001)
    Affinity Capture-Western
    hit Xia C (2001)
    Reconstituted Complex
    hit Xia C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARPC1B
  • ARC41
  • p40-ARC
  • p41-ARC
  • EG10095
    		•  The BioGRID Database Seperator ARP2/3 protein complex subunit p41|actin related protein 2/3 complex subunit 1B|actin related protein 2/3 complex, subunit 1A (41 kD)|actin related protein 2/3 complex, subunit 1B (41 kD); actin related protein 2/3 complex, subunit 1B, 41kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Vadlamudi RK (2004)
    Reconstituted Complex
    bait Vadlamudi RK (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAC1
  • MIG5
  • TC-25
  • p21-Rac1
  • EG5879
    		•  The BioGRID Database Seperator migration-inducing gene 5|migration-inducing protein 5|ras-related C3 botulinum toxin substrate 1|ras-related C3 botulinum toxin substrate 1 isoform Rac1b|rho family, small GTP binding protein Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Katoh H (2003)
    hit Seoh ML (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDK5
  • PSSALRE
  • EG1020
    		•  The BioGRID Database Seperator protein kinase CDK5 splicing; cyclin-dependent kinase 5
    Gene Ontology: [View List]
    Biochemical Activity
    bait Rashid T (2001)
    Affinity Capture-Western
    bait Rashid T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LIMK1
  • LIMK
  • EG3984
    		•  The BioGRID Database Seperator LIM motif-containing protein kinase; LIM domain kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Edwards DC (1999)
    Reconstituted Complex
    hit Edwards DC (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCK2
  • GRB4
  • NCKbeta
  • EG8440
    		•  The BioGRID Database Seperator SH2/SH3 adaptor protein NCK-beta|noncatalytic region of tyrosine kinase, beta; NCK adaptor protein 2
    Gene Ontology: [View List]
    Invivo
    hit Braverman LE (1999)
    Invitro
    hit Braverman LE (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF2
  • DKFZp547L...
  • GEF
  • GEF-H1
  • EG9181
    		•  The BioGRID Database Seperator proliferating cell nucleolar antigen p40|rho/rac guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor (GEF) 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Zenke FT (2004)
    Reconstituted Complex
    hit Zenke FT (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF7
  • BETA-PIX
  • COOL1
  • DKFZp761K...
  • EG8874
    		•  The BioGRID Database Seperator PAK-interacting exchange factor beta|Rho guanine nucleotide exchange factor 7|SH3 domain-containing proline-rich protein|putative protein product of Nbla10314|rho guanine nucleotide exchange factor 7; Rho guanine nucleotide exchange factor (GEF) 7
    Gene Ontology: [View List]
    Invivo
    bait Ku GM (2001)
    Invitro
    bait Ku GM (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMX
  • ETK
  • PSCTK2
  • PSCTK3
  • EG660
    		•  The BioGRID Database Seperator BMX non-receptor tyrosine kinase
    Gene Ontology: [View List]
    Invivo
    hit Bagheri-Yarmand R (2001)
    Invitro
    hit Bagheri-Yarmand R (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK1
  • PAKalpha
  • MGC130000
  • MGC130001
  • EG5058
    		•  The BioGRID Database Seperator p21-activated kinase 1|p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
    Gene Ontology: [View List]
    Invivo
    hit Parrini MC (2002)
    Invitro
    hit Parrini MC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    hit Zang M (2002)
    Invitro
    hit Zang M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHOJ
  • ARHJ
  • FLJ14445
  • RASL7B
  • EG57381
    		•  The BioGRID Database Seperator RAS-like, family 7, member B|TC10-like Rho GTPase; ras homolog gene family, member J
    Gene Ontology: [View List]
    Invitro
    hit Vignal E (2000)
    Two-hybrid
    hit Vignal E (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCK1
  • MGC12668
  • NCK
  • NCKalpha
  • EG4690
    		•  The BioGRID Database Seperator NCK tyrosine kinase|SH2/SH3 adaptor protein NCK-alpha|melanoma NCK protein|non-catalytic region of tyrosine kinase; NCK adaptor protein 1
    Gene Ontology: [View List]
    Invitro
    hit Bokoch GM (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PKLR
  • PK1
  • PKL
  • RPK
  • EG5313
    		•  The BioGRID Database Seperator R-type/L-type pyruvate kinase|pyruvate kinase 1|pyruvate kinase isozyme R/L|pyruvate kinase type L|pyruvate kinase, liver and RBC type|pyruvate kinase, liver and blood cell|red cell/liver pyruvate kinase; pyruvate kinase, liver and RBC
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Brown MC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG1
  • PLC-II
  • PLC1
  • PLC148
  • EG5335
    		•  The BioGRID Database Seperator 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phosphol...
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Shin KS (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABI3
  • NESH
  • SSH3BP3
  • EG51225
    		•  The BioGRID Database Seperator NESH protein|new molecule including SH3; ABI gene family, member 3
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Ichigotani Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF6
  • COOL2
  • Cool-2
  • KIAA0006
  • RP3-527F8.4
    		•  The BioGRID Database Seperator OTTHUMP00000062283|PAK-interacting exchange factor, alpha|Rac/Cdc42 guanine exchange factor (GEF) 6|Rac/Cdc42 guanine nucleotide exchange factor 6|mental retardation, X-linked 46|rho guanine nucleotide exchange factor 6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
    Gene Ontology: [View List]
    Invivo
    hit Manser E (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYLK
  • DKFZp686I...
  • FLJ12216
  • KRP
  • EG4638
    		•  The BioGRID Database Seperator myosin light chain kinase|myosin, light polypeptide kinase; myosin, light chain kinase
    Gene Ontology: [View List]
    Invitro
    bait Sanders LC (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     COL1A1
  • OI4
  • EG1277
    		•  The BioGRID Database Seperator Collagen I, alpha-1 polypeptide|alpha 1 type I collagen|collagen alpha 1 chain type I|collagen of skin, tendon and bone, alpha-1 chain|osteogenesis imperfecta type IV|pro-alpha-1 collagen type 1|type I collagen alpha 1 chain|type I collagen pro alpha 1(I) chain propeptide|type II procollagen...
    Gene Ontology: [View List]
    Invitro
    hit Francischetti IM (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPM1F
  • CaMKPase
  • FEM-2
  • KIAA0015
  • EG9647
    		•  The BioGRID Database Seperator Ca(2+)/calmodulin-dependent protein kinase phosphatase|CaM-kinase phosphatase|PP2C phosphatase|partner of PIX 2|protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing)
    Gene Ontology: [View List]
    Invivo
    bait Koh CG (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AKT1
  • MGC99656
  • PKB
  • PRKBA
  • EG207
    		•  The BioGRID Database Seperator RAC-alpha serine/threonine-protein kinase|murine thymoma viral (v-akt) oncogene homolog-1|protein kinase B|rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Vadlamudi RK (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC42
  • CDC42Hs
  • G25K
  • RP1-224A6.5
    		•  The BioGRID Database Seperator GTP-binding protein, 25kD|cell division cycle 42|cell division cycle 42 (GTP binding protein, 25kD)|cell division cycle 42 (GTP-binding protein, 25kD)|dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))|dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))|growth-regulating...
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Seoh ML (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HGS
  • HRS
  • ZFYVE8
  • EG9146
    		•  The BioGRID Database Seperator hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate
    Gene Ontology: [View List]
    Invivo
    hit Sasaki Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERBB2
  • HER-2
  • HER-2/neu
  • HER2
  • EG2064
    		•  The BioGRID Database Seperator c-erb B2/neu protein|erbB-2|herstatin|neuroblastoma/glioblastoma derived oncogene homolog|v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Adam L (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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