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SERPINE1
Homo sapiens
Aliases:
PLANH1, PAI-1, PAI1, PAI
Description:
serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Links:
[UniprotKB]
|
[OMIM]
|
[HPRD]
|
[Entrez Gene]
Gene Ontology:
9 total GO annotations for this record.
[view list]
Function
Process
Component
•
protein binding
(
IPI
)
•
protease binding
(
IPI
)
•
serine-type endopeptidase ...
(
EXP
)
•
fibrinolysis
(
TAS
)
•
chronological cell aging
(
IEP
)
•
blood coagulation
(
TAS
)
•
plasma membrane
(
EXP
)
•
extracellular region
(
NAS
)
•
extracellular region
(
EXP
)
Download interactions associated with SERPINE1
SERPINE1 was identified with
10
protein interactions
Name
Aliases
Description
Evidence Code
Role
Source [Interactions]
ORM1
ORM
AGP1
AGP-A
alpha-1-acid glycoprotein 1
Gene Ontology:
[View List]
Reconstituted Complex
hit
Boncela J (2001)
[
2
]
Two-hybrid
hit
Boncela J (2001)
[
2
]
PLAT
TPA
T-PA
DKFZp686I...
tissue plasminogen activator (t-PA)
Gene Ontology:
[View List]
Reconstituted Complex
hit
Madison EL (1990)
[
1
]
IGFBP5
IBP5
insulin-like growth factor binding protein 5
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Nam TJ (1997)
[
1
]
SERPINE1
PLANH1
PAI-1
PAI1
serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Gene Ontology:
[View List]
Co-crystal Structure
hit
Nar H (2000)
[
1
]
VTN
VNT
V75
VN
vitronectin (serum spreading factor, somatomedin B, complement S-protein)
Gene Ontology:
[View List]
Reconstituted Complex
bait
Mulligan-Kehoe MJ (2001)
[
2
]
LRP1
A2MR
LRP
APR
low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Degryse B (2004)
[
1
]
F2
PT
coagulation factor II (thrombin)
Gene Ontology:
[View List]
Reconstituted Complex
bait
Dekker RJ (2003)
[
1
]
PLG
DKFZp779M...
RP1-81D8.1
plasminogen
Gene Ontology:
[View List]
Reconstituted Complex
bait
Mulligan-Kehoe MJ (2001)
[
2
]
PLAU
URK
UPA
u-PA
urokinase-type plasminogen activator
Gene Ontology:
[View List]
Reconstituted Complex
bait
Nykjaer A (1997)
[
2
]
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Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.