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BioGRID | Network Layout for NCK1 for Homo sapiens
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NCK1

 Homo sapiens
The BioGRID Database Seperator
Aliases: MGC12668, NCK, NCKalpha, EG4690
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: NCK tyrosine kinase|SH2/SH3 adaptor protein NCK-alpha|melanoma NCK protein|non-catalytic region of tyrosine kinase; NCK adaptor protein 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 8 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with NCK1

NCK1 was identified with 67 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 SOS1
  • GF1
  • GGF1
  • GINGF
  • EG6654
    		•  The BioGRID Database Seperator gingival fibromatosis, hereditary, 1|son of sevenless homolog 1; son of sevenless homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Invivo
    bait Braverman LE (1999)
    Invitro
    bait Braverman LE (1999)
    Affinity Capture-Western
    hit Wunderlich L (1999)
    hit Hu Q (1995)
    Reconstituted Complex
    hit Hu Q (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KHDRBS1
  • Sam68
  • p62
  • FLJ34027
  • EG10657
    		•  The BioGRID Database Seperator KH domain containing, RNA binding, signal transduction associated 1; GAP-associated tyrosine phosphoprotein p62 (Sam68)
    Gene Ontology: [View List]
    Invivo
    bait Lawe DC (1997)
    Invitro
    bait Lawe DC (1997)
    Reconstituted Complex
    hit Tang J (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRAS
  • EG6237
    		•  The BioGRID Database Seperator related RAS viral (r-ras) oncogene homolog; Oncogene RRAS
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Wang B (2000)
    Affinity Capture-Western
    hit Wang B (2000)
    Two-hybrid
    hit Wang B (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WAS
  • IMD2
  • THC
  • WASP
  • EG7454
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome protein|thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
    Gene Ontology: [View List]
    Invivo
    hit Rivero-Lezcano OM (1995)
    Invitro
    hit Rivero-Lezcano OM (1995)
    Affinity Capture-Western
    bait Krause M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EIF2B2
  • EIF-2Bbeta
  • EIF2B
  • EG8892
    		•  The BioGRID Database Seperator eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Kebache S (2002)
    Reconstituted Complex
    hit Kebache S (2002)
    Two-hybrid
    hit Kebache S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WASL
  • DKFZp779G...
  • MGC48327
  • N-WASP
  • EG8976
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome gene-like|Wiskott-Aldrich syndrome gene-like protein|neural Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome-like
    Gene Ontology: [View List]
    Far Western
    bait Rohatgi R (2001)
    Reconstituted Complex
    hit Rohatgi R (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DNM1
  • DNM
  • EG1759
    		•  The BioGRID Database Seperator dynamin 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Wunderlich L (1999)
    Affinity Capture-Western
    hit Wunderlich L (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RICS
  • GC-GAP
  • GRIT
  • KIAA0712
  • EG9743
    		•  The BioGRID Database Seperator GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein; Rho GTPase-activating protein
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Zhao C (2003)
    Affinity Capture-Western
    bait Zhao C (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TBK1
  • FLJ11330
  • NAK
  • T2K
  • EG29110
    		•  The BioGRID Database Seperator NF-kB-activating kinase; TANK-binding kinase 1
    Gene Ontology: [View List]
    Invivo
    bait Chou MM (1995)
    Invitro
    bait Chou MM (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K4
  • FLH21957
  • FLJ20373
  • HGK
  • EG9448
    		•  The BioGRID Database Seperator HPK/GCK-like kinase|hepatocyte progenitor kinase-like/germinal center kinase-like kinase; mitogen-activated protein kinase kinase kinase kinase 4
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Su YC (1997)
    Affinity Capture-Western
    bait Su YC (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEDD9
  • CAS-L
  • CASL
  • HEF1
  • EG4739
    		•  The BioGRID Database Seperator Crk-associated substrate related|cas-like docking|dJ49G10.2 (Enhancer of Filamentation 1 (HEF1))|dJ761I2.1 (enhancer of filamentation (HEF1))|enhancer of filamentation 1; neural precursor cell expressed, developmentally down-regulated 9
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Minegishi M (1996)
    Reconstituted Complex
    hit Minegishi M (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAG1
  • 156DAG
  • A3a
  • AGRNR
  • EG1605
    		•  The BioGRID Database Seperator alpha-dystroglycan|beta-dystroglycan|dystroglycan 1|dystrophin-associated glycoprotein-1; dystroglycan 1 (dystrophin-associated glycoprotein 1)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Sotgia F (2001)
    Affinity Capture-Western
    bait Sotgia F (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MINK1
  • B55
  • MAP4K6
  • MGC21111
  • EG50488
    		•  The BioGRID Database Seperator GCK family kinase MINK|misshapen/NIK-related kinase|serine/threonine protein kinase; misshapen-like kinase 1 (zebrafish)
    Gene Ontology: [View List]
    Two-hybrid
    bait Hu Y (2004)
    Reconstituted Complex
    hit Hu Y (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Tang J (1997)
    Affinity Capture-Western
    hit Li W (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCP2
  • SLP-76
  • SLP76
  • EG3937
    		•  The BioGRID Database Seperator 76 kDa tyrosine phosphoprotein|SH2 domain-containing leukocyte protein of 76kD|lymphocyte cytosolic protein 2|lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shim EK (2004)
    Reconstituted Complex
    hit Wunderlich L (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOK2
  • p56DOK
  • p56dok-2
  • EG9046
    		•  The BioGRID Database Seperator docking protein 2, 56kDa; docking protein 2
    Gene Ontology: [View List]
    Invivo
    bait Master Z (2001)
    Invitro
    bait Master Z (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WASPIP
  • PRPL-2
  • WIP
  • MGC111041
  • EG7456
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome protein interacting protein; WAS/WASL interacting protein family, member 1
    Gene Ontology: [View List]
    Invivo
    bait Anton IM (1998)
    Invitro
    bait Anton IM (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NTRK2
  • GP145-TrkB
  • TRKB
  • EG4915
    		•  The BioGRID Database Seperator BDNF/NT-3 growth factors receptor|tyrosine kinase receptor B; neurotrophic tyrosine kinase, receptor, type 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Suzuki S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PXN
  • FLJ16691
  • hCG_1778014
    		•  The BioGRID Database Seperator paxillin
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Turner CE (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCAR1
  • CAS
  • CRKAS
  • P130Cas
  • EG9564
    		•  The BioGRID Database Seperator breast cancer anti-estrogen resistance 1; Crk-associated substrate p130Cas
    Gene Ontology: [View List]
    Invivo
    bait Okabe S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAC1
  • MIG5
  • TC-25
  • p21-Rac1
  • EG5879
    		•  The BioGRID Database Seperator migration-inducing gene 5|migration-inducing protein 5|ras-related C3 botulinum toxin substrate 1|ras-related C3 botulinum toxin substrate 1 isoform Rac1b|rho family, small GTP binding protein Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    Gene Ontology: [View List]
    Invivo
    bait Hummel T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K1
  • HPK1
  • EG11184
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase kinase kinase 1; hematopoietic progenitor kinase 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Anafi M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCKAP1
  • KIAA0587
  • MGC8981
  • NAP1
  • EG10787
    		•  The BioGRID Database Seperator NCK-associated protein 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Yamamoto A (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CRK
  • CRKII
  • EG1398
    		•  The BioGRID Database Seperator avian sarcoma virus CT10 (v-crk) oncogene homolog|v-crk avian sarcoma virus CT10 oncogene homolog|v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Minegishi M (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FASLG
  • APT1LG1
  • CD178
  • CD95L
  • EG356
    		•  The BioGRID Database Seperator CD95 ligand|apoptosis (APO-1) antigen ligand 1|fas ligand|tumor necrosis factor (ligand) superfamily, member 6; Fas ligand (TNF superfamily, member 6)
    Gene Ontology: [View List]
    Invivo
    hit Wenzel J (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDGFRB
  • CD140B
  • JTK12
  • PDGF-R-beta
  • EG5159
    		•  The BioGRID Database Seperator beta platelet-derived growth factor receptor|platelet-derived growth factor receptor beta; platelet-derived growth factor receptor, beta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Li W (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DCC
  • CRC18
  • CRCR1
  • EG1630
    		•  The BioGRID Database Seperator deleted in colorectal cancer protein; deleted in colorectal carcinoma
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Li X (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2
  • FADK
  • FAK
  • FAK1
  • EG5747
    		•  The BioGRID Database Seperator PTK2 protein tyrosine kinase 2; focal adhesion kinase 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Minegishi M (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPHB1
  • ELK
  • EPHT2
  • Hek6
  • EG2047
    		•  The BioGRID Database Seperator eph tyrosine kinase 2|ephrin receptor EphB1; EPH receptor B1
    Gene Ontology: [View List]
    Two-hybrid
    hit Stein E (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABL1
  • ABL
  • JTK7
  • c-ABL
  • RP11-83J2...
    		•  The BioGRID Database Seperator Abelson murine leukemia viral (v-abl) oncogene homolog 1|BCR/ABL fusion protein|bcr/c-abl oncogene protein|proto-oncogene tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    hit Miyoshi-Akiyama T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RASA1
  • CMAVM
  • DKFZp434N...
  • GAP
  • EG5921
    		•  The BioGRID Database Seperator GTPase activating protein|RAS p21 protein activator 1|triphosphatase-activating protein; RAS p21 protein activator (GTPase activating protein) 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Holland SJ (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DRD4
  • D4DR
  • EG1815
    		•  The BioGRID Database Seperator D(2C) dopamine receptor|seven transmembrane helix receptor; dopamine receptor D4
    Gene Ontology: [View List]
    Invivo
    bait Oldenhof J (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOCS7
  • NAP4
  • EG30837
    		•  The BioGRID Database Seperator Nck, Ash and phospholipase C binding protein; suppressor of cytokine signaling 7
    Gene Ontology: [View List]
    Invitro
    bait Matuoka K (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERBB4
  • HER4
  • MGC138404
  • p180erbB4
  • EG2066
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4|receptor tyrosine-protein kinase erbB-4|tyrosine kinase-type cell surface receptor HER4|v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4|v-erb-a erythroblastic leukemia viral oncogene homolog 4; ...
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Schulze WX (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCKIPSD
  • AF3P21
  • DIP
  • DIP1
  • EG51517
    		•  The BioGRID Database Seperator SH3 protein interacting with Nck, 90 kDa|dia interacting protein|diaphanous protein interacting protein; NCK interacting protein with SH3 domain
    Gene Ontology: [View List]
    Two-hybrid
    bait Lim CS (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK1
  • PAKalpha
  • MGC130000
  • MGC130001
  • EG5058
    		•  The BioGRID Database Seperator p21-activated kinase 1|p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
    Gene Ontology: [View List]
    Invitro
    bait Bokoch GM (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Mta1
  • MGC118456
  • EG116870
    		•  The BioGRID Database Seperator metastasis associated 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Simpson A (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Mta3
  • 1110002J2...
  • mKIAA1266
  • EG116871
    		•  The BioGRID Database Seperator metastasis associated 3
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Simpson A (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAV2
  • CAV
  • MGC12294
  • EG858
    		•  The BioGRID Database Seperator caveolae protein, 20-kD; caveolin 2
    Gene Ontology: [View List]
    Invivo
    bait Lee H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOCS1
  • CIS1
  • CISH1
  • JAB
  • EG8651
    		•  The BioGRID Database Seperator JAK binding protein|STAT induced SH3 protein 1|Tec-interacting protein 3|cytokine-inducible SH2 protein 1; suppressor of cytokine signaling 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit De Sepulveda P (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABI1
  • ABI-1
  • E3B1
  • NAP1BP
  • RP13-16H1...
    		•  The BioGRID Database Seperator Abelson interactor 1|Abl-interactor protein 1 long|eps8 binding protein|interactor protein AblBP4|nap1 binding protein|spectrin SH3 domain binding protein 1; abl-interactor 1
    Gene Ontology: [View List]