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MSH3
Homo sapiens
Aliases:
DUP, MRP1, MGC163306, MGC163308, EG4437
Description:
Divergent upstream protein|Mismatch repair protein 1|mutS homolog 3; mutS homolog 3 (E. coli)
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
13 total GO annotations for this record.
[view list]
Function
Process
Component
•
dinucleotide repeat inser ...
(
IDA
)
•
mismatched DNA binding
(
IDA
)
•
guanine/thymine mispair b ...
(
IDA
)
•
single guanine insertion ...
(
IDA
)
•
single-stranded DNA bindi ...
(
IDA
)
•
purine-specific mismatch ...
(
IMP
)
•
protein homodimerization ...
(
IDA
)
•
protein binding
(
IPI
)
•
oxidized purine DNA bindi ...
(
IDA
)
•
base-excision repair
(
IDA
)
•
maintenance of DNA repeat ...
(
IMP
)
•
mismatch repair
(
IMP
)
•
MutSbeta complex
(
IDA
)
Download interactions associated with MSH3
MSH3 was identified with
15
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
PCNA
MGC8367
EG5111
DNA polymerase delta auxiliary protein|cyclin; proliferating cell nuclear antigen
Gene Ontology:
[View List]
Far Western
hit
Kleczkowska HE (2001)
Affinity Capture-Western
hit
Kleczkowska HE (2001)
bait
Ohta S (2002)
Protein-peptide
hit
Clark AB (2000)
Affinity Capture-MS
bait
Ohta S (2002)
MSH2
COCA1
FCC1
HNPCC
EG4436
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); mutS homolog 2
Gene Ontology:
[View List]
Invivo
bait
Acharya S (1996)
Invitro
bait
Acharya S (1996)
Two-hybrid
bait
Acharya S (1996)
Affinity Capture-MS
bait
Wang Y (2003)
Reconstituted Complex
bait
Guerrette S (1998)
BRCA1
BRCAI
IRIS
PSCP
EG672
BRCA1/BRCA2-containing complex, subunit 1|breast and ovarian cancer susceptibility protein 1; breast cancer 1, early onset
Gene Ontology:
[View List]
Protein-peptide
bait/hit
Rodriguez M (2003)
Reconstituted Complex
bait
Wang Q (2001)
EXO1
HEX1
hExoI
EG9156
rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1; exonuclease 1
Gene Ontology:
[View List]
Invivo
hit
Schmutte C (2001)
Invitro
hit
Schmutte C (2001)
BARD1
EG580
BRCA1-associated RING domain 1|BRCA1-associated RING domain gene 1; BRCA1 associated RING domain 1
Gene Ontology:
[View List]
Reconstituted Complex
bait
Wang Q (2001)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.