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MMP14
Homo sapiens
Aliases:
MMP-X1, MT1-MMP, MTMMP1, EG4323
Description:
matrix metalloproteinase 14|matrix metalloproteinase 14 (membrane-inserted)|membrane type 1 metalloprotease|membrane-type matrix metalloproteinase 1|membrane-type-1 matrix metalloproteinase; matrix metallopeptidase 14 (membrane-inserted)
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
5 total GO annotations for this record.
[view list]
Function
Process
Component
•
metalloendopeptidase acti ...
(
TAS
)
•
zinc ion binding
(
TAS
)
•
protein binding
(
IPI
)
•
proteolysis
(
TAS
)
•
integral to plasma membra ...
(
TAS
)
Download interactions associated with MMP14
MMP14 was identified with
6
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
TIMP2
CSC-21K
EG7077
tissue inhibitor of metalloproteinase 2|tissue inhibitor of metalloproteinases 2; TIMP metallopeptidase inhibitor 2
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Zucker S (1998)
Reconstituted Complex
bait
Zucker S (1998)
SPOCK3
HSAJ1454
TES-3
EG50859
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3; testican 3
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Nakada M (2001)
C1QBP
GC1QBP
HABP1
SF2p32
EG708
C1q globular domain-binding protein|hyaluronan-binding protein 1|splicing factor SF2-associated protein; complement component 1, q subcomponent binding protein
Gene Ontology:
[View List]
Protein-peptide
hit
Rozanov DV (2002)
LUM
LDC
SLRR2D
EG4060
lumican proteoglycan; lumican
Gene Ontology:
[View List]
Biochemical Activity
hit
Li Y (2004)
LRP1
A2MR
APOER
APR
EG4035
alpha-2-macroglobulin receptor|low density lipoprotein-related protein 1|type V tgf-beta receptor; low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Rozanov DV (2004)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.