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BioGRID | Network Layout for MLL for Homo sapiens
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MLL

 Homo sapiens
The BioGRID Database Seperator
Aliases: ALL-1, CXXC7, HRX, HTRX1, MLL1A, TRX1, MLL/GAS7, FLJ11783, KMT2A, hCG_1732268
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: AF4/MLL fusion protein|CDK6/MLL fusion protein|MLL-AF4 der(11) fusion protein|MLL/GAS7 fusion protein|MLL/GMPS fusion protein|trithorax-like protein|zinc finger protein HRX; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 7 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MLL

MLL was identified with 38 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MLL
  • ALL-1
  • CXXC7
  • HRX
  • hCG_1732268
    		•  The BioGRID Database Seperator AF4/MLL fusion protein|CDK6/MLL fusion protein|MLL-AF4 der(11) fusion protein|MLL/GAS7 fusion protein|MLL/GMPS fusion protein|trithorax-like protein|zinc finger protein HRX; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Fair K (2001)
    Reconstituted Complex
    hit Fair K (2001)
    hit Hsieh JJ (2003)
    hit Yokoyama A (2002)
    Affinity Capture-Western
    hit Hsieh JJ (2003)
    hit Yokoyama A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CREBBP
  • CBP
  • RSTS
  • RTS
  • EG1387
    		•  The BioGRID Database Seperator CREB binding protein (Rubinstein-Taybi syndrome); CREB binding protein|CREB-binding protein
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Goto NK (2002)
    bait/hit Ernst P (2001)
    Co-crystal Structure
    bait Goto NK (2002)
    Affinity Capture-Western
    bait Ernst P (2001)
    Two-hybrid
    bait Ernst P (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPIE
  • CYP-33
  • MGC3736
  • MGC111222
  • RP1-118J2...
    		•  The BioGRID Database Seperator PPIase E|cyclophilin 33|cyclophilin E|peptidyl-prolyl cis-trans isomerase E|peptidylprolyl isomerase E|peptidylprolyl isomerase E, isoform 1|rotamase E; peptidylprolyl isomerase E (cyclophilin E)
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Fair K (2001)
    Affinity Capture-Western
    bait/hit Fair K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HDAC1
  • HD1
  • RPD3
  • RPD3L1
  • EG3065
    		•  The BioGRID Database Seperator reduced potassium dependency, yeast homolog-like 1; histone deacetylase 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Xia ZB (2003)
    Affinity Capture-Western
    hit Xia ZB (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WDR5
  • BIG-3
  • SWD3
  • EG11091
    		•  The BioGRID Database Seperator BMP2-induced 3-kb gene protein|SWD3, Set1c WD40 repeat protein, homolog|WD-repeat protein 5; WD repeat domain 5
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Yokoyama A (2004)
    Co-purification
    hit Yokoyama A (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTBP1
  • MGC104684
  • BARS
  • EG1487
    		•  The BioGRID Database Seperator brefeldin A-ribosylated substrate; C-terminal binding protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Xia ZB (2003)
    Affinity Capture-Western
    hit Xia ZB (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RBBP5
  • RBQ3
  • SWD1
  • EG5929
    		•  The BioGRID Database Seperator SWD1, Set1c WD40 repeat protein, homolog|retinoblastoma-binding protein 5; retinoblastoma binding protein 5
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Yokoyama A (2004)
    Co-purification
    hit Yokoyama A (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HCFC1
  • HCF-1
  • HCF1
  • HFC1
  • EG3054
    		•  The BioGRID Database Seperator host cell factor C1 (VP16-accessory protein); host cell factor 1
    Gene Ontology: [View List]
    Co-purification
    hit Yokoyama A (2004)
    Affinity Capture-Western
    bait/hit Yokoyama A (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP1R15A
  • GADD34
  • EG23645
    		•  The BioGRID Database Seperator growth arrest and DNA-damage-inducible 34|protein phosphatase 1, regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A
    Gene Ontology: [View List]
    Two-hybrid
    hit Adler HT (1999)
    Affinity Capture-Western
    hit Adler HT (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HCFC2
  • HCF-2
  • HCF2
  • EG29915
    		•  The BioGRID Database Seperator host cell factor C2; host cell factor 2
    Gene Ontology: [View List]
    Co-purification
    hit Yokoyama A (2004)
    Affinity Capture-Western
    bait/hit Yokoyama A (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MEN1
  • MEAI
  • SCG2
  • EG4221
    		•  The BioGRID Database Seperator Wermer syndrome|Zollinger-Ellison syndrome|endocrine adenomatosis, multiple|menin; multiple endocrine neoplasia I
    Gene Ontology: [View List]
    Co-purification
    hit Yokoyama A (2004)
    Affinity Capture-Western
    bait/hit Yokoyama A (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ASH2L
  • ASH2L1
  • ASH2L2
  • ASH2
  • EG9070
    		•  The BioGRID Database Seperator ash2 (absent, small, or homeotic)-like (Drosophila); ash2-like
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Yokoyama A (2004)
    Co-purification
    hit Yokoyama A (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMARCB1
  • BAF47
  • INI1
  • RDT
  • EG6598
    		•  The BioGRID Database Seperator integrase interactor 1|malignant rhabdoid tumor suppressor|sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Adler HT (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBX4
  • NBP16
  • PC2
  • hPC2
  • EG8535
    		•  The BioGRID Database Seperator chromobox homolog 4 (Pc class homolog, Drosophila); NS5ATP1-binding protein 16|chromobox homolog 4
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Xia ZB (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PCGF4
  • BMI1
  • MGC12685
  • RNF51
  • RP11-573G...
    		•  The BioGRID Database Seperator B lymphoma Mo-MLV insertion region 1 homolog|flvi-2/bmi-1|murine leukemia viral (bmi-1) oncogene homolog|oncogene BMI-1|polycomb group ring finger 4; BMI1 polycomb ring finger oncogene
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Xia ZB (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AVP
  • ADH
  • ARVP
  • AVP-NPII
  • EG551
    		•  The BioGRID Database Seperator arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal); arginine vasopressin-neurophysin II|vasopressin-neurophysin II-copeptin
    Gene Ontology: [View List]
    Biochemical Activity
    hit Jeong W (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     INS
  • EG3630
    		•  The BioGRID Database Seperator proinsulin; insulin
    Gene Ontology: [View List]
    Biochemical Activity
    hit Jeong W (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OXT
  • OT
  • OT-NPI
  • MGC126890
  • EG5020
    		•  The BioGRID Database Seperator oxytocin-neurophysin I|oxytocin-neurophysin I, preproprotein; oxytocin, prepro- (neurophysin I)
    Gene Ontology: [View List]
    Biochemical Activity
    hit Jeong W (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K5
  • ASK1
  • MAPKKK5
  • MEKK5
  • RP3-325F2...
    		•  The BioGRID Database Seperator MAP/ERK kinase kinase 5|MAPK/ERK kinase kinase 5|apoptosis signal regulating kinase; mitogen-activated protein kinase kinase kinase 5
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Jeong W (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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    BioGRID: A General Repository for Interaction Datasets.
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