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BioGRID | Network Layout for MLH1 for Homo sapiens
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MLH1

 Homo sapiens
The BioGRID Database Seperator
Aliases: COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1, EG4292
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); DNA mismatch repair protein Mlh1|MutL protein homolog 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 5 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MLH1

MLH1 was identified with 42 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 BLM
  • BS
  • RECQ2
  • RECQL2
  • EG641
    		•  The BioGRID Database Seperator Bloom syndrome protein; Bloom syndrome
    Gene Ontology: [View List]
    Invivo
    hit Pedrazzi G (2001)
    Invitro
    hit Pedrazzi G (2001)
    Two-hybrid
    bait/hit Pedrazzi G (2001)
    bait Langland G (2001)
    Far Western
    bait Pedrazzi G (2001)
    bait Langland G (2001)
    bait Freire R (2001)
    Affinity Capture-Western
    bait Pedrazzi G (2001)
    bait Langland G (2001)
    Co-purification
    hit Wang Y (2000)
    Reconstituted Complex
    bait Langland G (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PMS2
  • HNPCC4
  • PMS2CL
  • PMSL2
  • EG5395
    		•  The BioGRID Database Seperator DNA mismatch repair|H_DJ0042M02.9|PMS2 postmeiotic segregation increased 2|postmeiotic segregation increased (S. cerevisiae) 2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
    Gene Ontology: [View List]
    Invivo
    hit Guerrette S (1999)
    Invitro
    hit Guerrette S (1999)
    Two-hybrid
    hit Guerrette S (1999)
    hit Mac Partlin M (2003)
    bait/hit Kondo E (2001)
    Reconstituted Complex
    hit Mac Partlin M (2003)
    hit Kondo E (2001)
    Affinity Capture-Western
    bait Kondo E (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYC
  • c-Myc
  • EG4609
    		•  The BioGRID Database Seperator avian myelocytomatosis viral oncogene homolog|myc proto-oncogene protein|v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Mac Partlin M (2003)
    Reconstituted Complex
    hit Mac Partlin M (2003)
    Affinity Capture-Western
    bait Mac Partlin M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MBD4
  • MED1
  • EG8930
    		•  The BioGRID Database Seperator 3,N(4)-ethenocytosine glycosylase|G/5-fluorouracil mismatch glycosylase with biphasic kinetics|G/T mismatch glycosylase|G/U mismatch glycosylase|putative methyl-CpG binding protein; methyl-CpG binding domain protein 4
    Gene Ontology: [View List]
    Invivo
    hit Bellacosa A (1999)
    Two-hybrid
    hit Bellacosa A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSH4
  • RP11-262K...
    		•  The BioGRID Database Seperator mutS homolog 4 (E. coli); mutS homolog 4
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Santucci-Darmanin S (2000)
    Reconstituted Complex
    bait Santucci-Darmanin S (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD50
  • RAD50-2
  • hRad50
  • EG10111
    		•  The BioGRID Database Seperator RAD50 homolog (S. cerevisiae); RAD50 homolog
    Gene Ontology: [View List]
    Co-purification
    bait Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NBS1
  • AT-V1
  • AT-V2
  • ATV
  • EG4683
    		•  The BioGRID Database Seperator Nijmegen breakage syndrome 1 (nibrin)|p95 protein of the MRE11/RAD50 complex; nibrin
    Gene Ontology: [View List]
    Co-purification
    bait Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSH6
  • GTBP
  • HNPCC5
  • HSAP
  • EG2956
    		•  The BioGRID Database Seperator G/T mismatch-binding protein|mutS homolog 6|sperm-associated protein; mutS homolog 6 (E. coli)
    Gene Ontology: [View List]
    Co-purification
    bait Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PMS1
  • DKFZp781M...
  • HNPCC3
  • PMSL1
  • EG5378
    		•  The BioGRID Database Seperator PMS1 nirs variant 3|human homolog of yeast mutL|postmeiotic segregation 1|postmeiotic segregation increased (S. cerevisiae) 1|rhabdomyosarcoma antigen MU-RMS-40.10B|rhabdomyosarcoma antigen MU-RMS-40.10E; PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
    Gene Ontology: [View List]
    Two-hybrid
    bait Kondo E (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSH2
  • COCA1
  • FCC1
  • HNPCC
  • EG4436
    		•  The BioGRID Database Seperator mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); mutS homolog 2
    Gene Ontology: [View List]
    Co-purification
    bait Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MLH3
  • HNPCC7
  • MGC138372
  • EG27030
    		•  The BioGRID Database Seperator DNA mismatch repair protein MLH3|mutL homolog 3; mutL homolog 3 (E. coli)
    Gene Ontology: [View List]
    Two-hybrid
    bait Kondo E (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RFC1
  • A1
  • MGC51786
  • MHCBFB
  • EG5981
    		•  The BioGRID Database Seperator MHC binding factor, beta|replication factor C (activator 1) 1 (145kD)|replication factor C large subunit|replication factor C1; replication factor C (activator 1) 1, 145kDa
    Gene Ontology: [View List]
    Co-purification
    hit Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRCA1
  • BRCAI
  • IRIS
  • PSCP
  • EG672
    		•  The BioGRID Database Seperator BRCA1/BRCA2-containing complex, subunit 1|breast and ovarian cancer susceptibility protein 1; breast cancer 1, early onset
    Gene Ontology: [View List]
    Co-purification
    bait Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZC3HDC11A
  • DKFZp686D...
  • DKFZp686F...
  • DKFZp781G...
  • EG9877
    		•  The BioGRID Database Seperator zinc finger CCCH-type domain containing 11A; zinc finger CCCH-type containing 11A
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRIM29
  • ATDC
  • FLJ36085
  • EG23650
    		•  The BioGRID Database Seperator ataxia-telangiectasia group D-associated protein|tripartite motif protein TRIM29; tripartite motif-containing 29
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AP2B1
  • ADTB2
  • AP2-BETA
  • CLAPB1
  • EG163
    		•  The BioGRID Database Seperator adaptin, beta 2 (beta)|clathrin assembly protein complex 2 beta large chain|clathrin-associated/assembly/adaptor protein, large, beta 1|plasma membrane adaptor HA2/AP2 adaptin beta subunit; adaptor-related protein complex 2, beta 1 subunit
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     C14orf31
  • MGC17921
  • c14_5320
  • FRMD6
  • EG122786
    		•  The BioGRID Database Seperator 4.1 ezrin radixin moesin (FERM)-containing protein; FERM domain containing 6
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBOX5
  • KIAA0860
  • RNF37
  • UBCE7IP5
  • EG22888
    		•  The BioGRID Database Seperator ring finger protein 37|ubiquitin conjugating enzyme 7 interacting protein 5; U-box domain containing 5
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EXO1
  • HEX1
  • hExoI
  • EG9156
    		•  The BioGRID Database Seperator rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1; exonuclease 1
    Gene Ontology: [View List]
    Invivo
    hit Schmutte C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATM
  • AT1
  • ATA
  • ATC
  • EG472
    		•  The BioGRID Database Seperator AT complementation group A|AT complementation group C|AT complementation group D|AT complementation group E|AT mutated|AT protein|TEL1, telomere maintenance 1, homolog|ataxia telangiectasia mutated (includes complementation groups A, C and D)|ataxia telangiectasia mutated protein...
    Gene Ontology: [View List]
    Co-purification
    hit Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MRE11A
  • ATLD
  • HNGS1
  • MRE11
  • EG4361
    		•  The BioGRID Database Seperator AT-like disease|DNA recombination and repair protein|double-strand break repair protein MRE11A|endo/exonuclease Mre11|meiotic recombination (S. cerevisiae) 11 homolog A|meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    Gene Ontology: [View List]
    Co-purification
    bait Wang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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