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BioGRID | Network Layout for MAP3K5 for Homo sapiens
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MAP3K5

 Homo sapiens
The BioGRID Database Seperator
Aliases: ASK1, MAPKKK5, MEKK5, RP3-325F22.4
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: MAP/ERK kinase kinase 5|MAPK/ERK kinase kinase 5|apoptosis signal regulating kinase; mitogen-activated protein kinase kinase kinase 5
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 10 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MAP3K5

MAP3K5 was identified with 57 protein interactions and 1 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 TXN
  • MGC61975
  • TRX
  • DKFZp686B...
  • EG7295
    		•  The BioGRID Database Seperator thioredoxin
    Gene Ontology: [View List]
    Invivo
    bait Saitoh M (1998)
    Invitro
    bait Saitoh M (1998)
    Two-hybrid
    bait Saitoh M (1998)
    Reconstituted Complex
    bait Liu Y (2002)
    Affinity Capture-Western
    bait Liu Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDCD6
  • ALG-2
  • MGC9123
  • PEF1B
  • EG10016
    		•  The BioGRID Database Seperator apoptosis-linked gene 2|apoptosis-linked gene-2; programmed cell death 6
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Hwang IS (2002)
    Reconstituted Complex
    bait Hwang IS (2002)
    Co-localization
    hit Hwang IS (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K5
  • ASK1
  • MAPKKK5
  • MEKK5
  • RP3-325F2...
    		•  The BioGRID Database Seperator MAP/ERK kinase kinase 5|MAPK/ERK kinase kinase 5|apoptosis signal regulating kinase; mitogen-activated protein kinase kinase kinase 5
    Gene Ontology: [View List]
    Invitro
    hit Tobiume K (2002)
    Two-hybrid
    hit Tobiume K (2002)
    Affinity Capture-Western
    bait/hit Zou X (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF2
  • MGC:45012
  • TRAP
  • TRAP3
  • EG7186
    		•  The BioGRID Database Seperator OTTHUMP00000064745|tumor necrosis factor type 2 receptor associated protein 3; TNF receptor-associated factor 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nishitoh H (1998)
    hit Hoeflich KP (1999)
    bait Gan B (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAXX
  • BING2
  • DAP6
  • MGC126245
  • DAQB-126H...
    		•  The BioGRID Database Seperator death-associated protein 6
    Gene Ontology: [View List]
    Invivo
    bait Chang HY (1998)
    Invitro
    bait Chang HY (1998)
    Two-hybrid
    bait Chang HY (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC25A
  • CDC25A2
  • EG993
    		•  The BioGRID Database Seperator M-phase inducer phosphatase 1|cell division cycle 25A|dual specificity phosphatase CDC25A; cell division cycle 25 homolog A (S. pombe)
    Gene Ontology: [View List]
    Two-hybrid
    bait Zou X (2001)
    Affinity Capture-Western
    bait/hit Zou X (2001)
    Reconstituted Complex
    hit Zou X (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K6
  • ASK2
  • MAPKKK6
  • MGC20114
  • EG9064
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase kinase 6; apoptosis signal-regulating kinase 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Wang XS (1998)
    Two-hybrid
    bait Wang XS (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF5
  • MGC:39780
  • RNF84
  • EG7188
    		•  The BioGRID Database Seperator TNF receptor-associated factor 5; RING finger protein 84
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nishitoh H (1998)
    hit Hoeflich KP (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSPA1A
  • HSP70-1
  • HSP72
  • HSPA1
  • DAQB-147D...
    		•  The BioGRID Database Seperator dnaK-type molecular chaperone HSP70-1|heat shock 70kD protein 1A|heat shock 70kDa protein 1B|heat shock-induced protein; heat shock 70kDa protein 1A
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Park HS (2002)
    Affinity Capture-Western
    hit Park HS (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF6
  • MGC:3310
  • RNF85
  • EG7189
    		•  The BioGRID Database Seperator TNF receptor-associated factor 6
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nishitoh H (1998)
    hit Hoeflich KP (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSTM1
  • GST1
  • GSTM1-1
  • GSTM1a-1a
  • EG2944
    		•  The BioGRID Database Seperator GST class-mu 1|HB subunit 4|S-(hydroxyalkyl)glutathione lyase|glutathione S-alkyltransferase|glutathione S-aralkyltransferase|glutathione S-aryltransferase|glutathione S-transferase, Mu-1; glutathione S-transferase M1
    Gene Ontology: [View List]
    Invivo
    bait Dorion S (2002)
    Invitro
    bait Dorion S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Gstm1
  • Gstb-1
  • Gstb1
  • RP23-214E...
    		•  The BioGRID Database Seperator glutathione S-transferase, mu 1; glutathione-S-transferase, mu 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Cho SG (2001)
    Reconstituted Complex
    hit Cho SG (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EIF2AK2
  • EIF2AK1
  • PKR
  • PRKR
  • EG5610
    		•  The BioGRID Database Seperator double stranded RNA activated protein kinase|interferon-inducible elF2alpha kinase|protein kinase, interferon-inducible double stranded RNA dependent; eukaryotic translation initiation factor 2-alpha kinase 2
    Gene Ontology: [View List]
    Invivo
    bait Takizawa T (2002)
    Invitro
    bait Takizawa T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invitro
    bait Chen J (2001)
    Invivo
    bait Chen J (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K7
  • TAK1
  • TGF1a
  • EG6885
    		•  The BioGRID Database Seperator TGF-beta activated kinase 1|transforming growth factor-beta-activated kinase 1; mitogen-activated protein kinase kinase kinase 7
    Gene Ontology: [View List]
    Invivo
    bait Mochida Y (2000)
    Two-hybrid
    bait Mochida Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP5C
  • PP5
  • PPP5
  • FLJ36922
  • EG5536
    		•  The BioGRID Database Seperator protein phosphatase 5, catalytic subunit; Serine/Threonine phosphatase
    Gene Ontology: [View List]
    Invivo
    bait Morita K (2001)
    Two-hybrid
    bait Morita K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GADD45B
  • DKFZP566B...
  • GADD45BETA
  • MYD118
  • EG4616
    		•  The BioGRID Database Seperator growth arrest and DNA-damage-inducible beta|myeloid differentiation primary response; growth arrest and DNA-damage-inducible, beta
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Papa S (2004)
    Reconstituted Complex
    bait Papa S (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8IP3
  • DKFZp762N...
  • FLJ00027
  • JIP3
  • AC012180.8
    		•  The BioGRID Database Seperator C-jun-amino-terminal kinase interacting protein 3|JNK-interacting protein 3|JNK/SAPK-associated protein-1|JNK/stress-activated protein kinase-associated protein 1|homolog of Drosophila Sunday driver 2; mitogen-activated protein kinase 8 interacting protein 3
    Gene Ontology: [View List]
    Invivo
    bait Matsuura H (2002)
    Invitro
    bait Matsuura H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DUSP19
  • DUSP17
  • SKRP1
  • TS-DSP1
  • EG142679
    		•  The BioGRID Database Seperator protein phosphatase|stress-activated protein kinase pathway-regulating phosphatase 1; dual specificity phosphatase 19
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zama T (2002)
    Phenotypic Enhancement
    hit Zama T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Rb1cc1
  • 2900055E0...
  • 5930404L0...
  • Cc1
  • EG12421
    		•  The BioGRID Database Seperator 200 kDa FAK family kinase-interacting protein|coiled coil forming protein 1; RB1-inducible coiled-coil 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Gan B (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAZ
  • KCIP-1
  • MGC111427
  • MGC126532
  • EG7534
    		•  The BioGRID Database Seperator 14-3-3 protein/cytosolic phospholipase A2|14-3-3 zeta|phospholipase A2|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Zhang L (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERN1
  • FLJ30999
  • IRE1
  • IRE1P
  • EG2081
    		•  The BioGRID Database Seperator ER to nucleus signalling 1|endoplasmic reticulum to nucleus signalling 1|inositol-requiring 1|protein kinase/endoribonuclease; endoplasmic reticulum to nucleus signaling 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nishitoh H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K6
  • MAPKK6
  • MEK6
  • MKK6
  • EG5608
    		•  The BioGRID Database Seperator protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); mitogen-activated protein kinase kinase 6
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Huang S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF3
  • CAP-1
  • CD40bp
  • CRAF1
  • EG7187
    		•  The BioGRID Database Seperator CD40 associated protein 1|CD40 binding protein|CD40 receptor associated factor 1|LMP1 associated protein; TNF receptor-associated factor 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nishitoh H (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MLL
  • ALL-1
  • CXXC7
  • HRX
  • hCG_1732268
    		•  The BioGRID Database Seperator AF4/MLL fusion protein|CDK6/MLL fusion protein|MLL-AF4 der(11) fusion protein|MLL/GAS7 fusion protein|MLL/GMPS fusion protein|trithorax-like protein|zinc finger protein HRX; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Jeong W (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GLRX
  • GRX
  • GRX1
  • MGC117407
  • EG2745
    		•  The BioGRID Database Seperator glutaredoxin (thioltransferase)
    Gene Ontology: [View List]
    Invitro
    hit Song JJ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF1
  • EBI6
  • MGC:10353
  • EG7185
    		•  The BioGRID Database Seperator Epstein-Bar virus-induced protein 6; TNF receptor-associated factor 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nishitoh H (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     QARS
  • GLNRS
  • PRO2195
  • EG5859
    		•  The BioGRID Database Seperator glutamine tRNA ligase|glutamine-tRNA synthetase; glutaminyl-tRNA synthetase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ko YG (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDKN1A
  • CAP20
  • CDKN1
  • CIP1
  • EG1026
    		•  The BioGRID Database Seperator CDK-interaction protein 1|DNA synthesis inhibitor|cyclin-dependent kinase inhibitor 1A|melanoma differentiation associated protein 6|wild-type p53-activated fragment 1; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Huang S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K7
  • Jnkk2
  • MAPKK7
  • MKK7
  • EG5609
    		•  The BioGRID Database Seperator JNK kinase 2|JNK-activating kinase 2|MAP kinase kinase 7|c-Jun N-terminal kinase kinase 2|dual specificity mitogen-activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zama T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RB1CC1
  • CC1
  • DRAGOU14
  • FIP200
  • EG9821
    		•  The BioGRID Database Seperator 200 kDa FAK family kinase-interacting protein|Rb1-inducible coiled coil protein 1; RB1-inducible coiled-coil 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Gan B (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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