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BioGRID | Network Layout for MAP3K1 for Homo sapiens
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MAP3K1

 Homo sapiens
The BioGRID Database Seperator
Aliases: MAPKKK1, MEKK, MEKK1, EG4214
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: MAP/ERK kinase kinase 1|MAPK/ERK kinase kinase 1|MEK kinase 1; mitogen-activated protein kinase kinase kinase 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MAP3K1

MAP3K1 was identified with 30 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MAPK8
  • JNK
  • JNK1
  • JNK1A2
  • EG5599
    		•  The BioGRID Database Seperator JNK1 alpha protein kinase|JNK1 beta protein kinase|c-Jun N-terminal kinase 1|protein kinase JNK1|stress-activated protein kinase JNK1; mitogen-activated protein kinase 8
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Xu S (1997)
    Reconstituted Complex
    hit Xu S (1997)
    Biochemical Activity
    bait Xu S (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Invivo
    hit Pomerance M (1998)
    Invitro
    hit Pomerance M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBE2I
  • C358B7.1
  • P18
  • UBC9
  • EG7329
    		•  The BioGRID Database Seperator SUMO-1-protein ligase|ubiquitin carrier protein|ubiquitin conjugating enzyme 9|ubiquitin-conjugating enzyme E2I|ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9)|ubiquitin-conjugating enzyme UbcE2A|ubiquitin-like protein SUMO-1 conjugating enzyme|ubiquitin-protein ligas...
    Gene Ontology: [View List]
    Two-hybrid
    bait Saltzman A (1998)
    Reconstituted Complex
    bait Saltzman A (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AXIN1
  • AXIN
  • MGC52315
  • LA16c-314...
    		•  The BioGRID Database Seperator axis inhibition protein 1|axis inhibitor 1|fused, mouse, homolog of; axin 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Zhang Y (2002)
    bait/hit Zhang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    bait Karandikar M (2000)
    Invitro
    bait Karandikar M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS13
  • EG6207
    		•  The BioGRID Database Seperator 40S ribosomal protein S13; ribosomal protein S13
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL4
  • EG6124
    		•  The BioGRID Database Seperator 60S ribosomal protein L4; ribosomal protein L4
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8IP3
  • DKFZp762N...
  • FLJ00027
  • JIP3
  • AC012180.8
    		•  The BioGRID Database Seperator C-jun-amino-terminal kinase interacting protein 3|JNK-interacting protein 3|JNK/SAPK-associated protein-1|JNK/stress-activated protein kinase-associated protein 1|homolog of Drosophila Sunday driver 2; mitogen-activated protein kinase 8 interacting protein 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ito M (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAE
  • 14-3-3E
  • KCIP-1
  • MDCR
  • EG7531
    		•  The BioGRID Database Seperator 14-3-3 epsilon|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Fanger GR (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K4
  • FLH21957
  • FLJ20373
  • HGK
  • EG9448
    		•  The BioGRID Database Seperator HPK/GCK-like kinase|hepatocyte progenitor kinase-like/germinal center kinase-like kinase; mitogen-activated protein kinase kinase kinase kinase 4
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Su YC (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL30
  • EG6156
    		•  The BioGRID Database Seperator 60S ribosomal protein L30; ribosomal protein L30
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K2
  • BL44
  • GCK
  • RAB8IP
  • EG5871
    		•  The BioGRID Database Seperator B lymphocyte serine/threonine protein kinase|Rab8 interacting protein|germinal centre kinase (GC kinase); mitogen-activated protein kinase kinase kinase kinase 2
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Yuasa T (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DVL2
  • EG1856
    		•  The BioGRID Database Seperator DSH homolog 2|dishevelled 2|dishevelled 2 (homologous to Drosophila dsh)|segment polarity protein dishevelled homolog DVL-2; dishevelled, dsh homolog 2 (Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Zhang Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WDR68
  • AN11
  • HAN11
  • EG10238
    		•  The BioGRID Database Seperator WD repeat domain 68; WD-repeat protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K4
  • JNKK
  • JNKK1
  • MAPKK4
  • EG6416
    		•  The BioGRID Database Seperator JNK activating kinase 1|JNK-activated kinase 1|MAP kinase kinase 4|MAPK/ERK kinase 4|SAPK/ERK kinase 1|c-Jun N-terminal kinase kinase 1|dual specificity mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4
    Gene Ontology: [View List]
    Invivo
    bait Guan Z (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHUK
  • IKBKA
  • IKK-alpha
  • IKK1
  • EG1147
    		•  The BioGRID Database Seperator I-kappa-B kinase 1|I-kappa-B kinase-alpha|IKK-a kinase|IkB kinase alpha subunit|Nuclear factor NFkappaB inhibitor kinase alpha|conserved helix-loop ubiquitous kinase; conserved helix-loop-helix ubiquitous kinase
    Gene Ontology: [View List]
    Invivo
    bait Nemoto S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K10
  • MLK2
  • MST
  • EG4294
    		•  The BioGRID Database Seperator MKN28 derived nonreceptor_type serine/threonine kinase|MKN28 kinase|mixed lineage kinase 2; mitogen-activated protein kinase kinase kinase 10
    Gene Ontology: [View List]
    Invivo
    bait Hirai S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK3
  • CDKN1A
  • MRX30
  • OPHN3
  • RP5-914P1...
    		•  The BioGRID Database Seperator OTTHUMP00000062894|oligophrenin-3|p21-activated kinase 3|p21-activated kinase-3; p21 (CDKN1A)-activated kinase 3
    Gene Ontology: [View List]
    Invivo
    bait Siow YL (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF2
  • MGC:45012
  • TRAP
  • TRAP3
  • EG7186
    		•  The BioGRID Database Seperator OTTHUMP00000064745|tumor necrosis factor type 2 receptor associated protein 3; TNF receptor-associated factor 2
    Gene Ontology: [View List]
    Invivo
    bait Baud V (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IKBKB
  • IKK-beta
  • IKK2
  • IKKB
  • EG3551
    		•  The BioGRID Database Seperator inhibitor of nuclear factor kappa B kinase beta subunit|nuclear factor NF-kappa-B inhibitor kinase beta; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
    Gene Ontology: [View List]
    Invivo
    bait Nemoto S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FKBP5
  • FKBP51
  • FKBP54
  • P54
  • EG2289
    		•  The BioGRID Database Seperator 51 kDa FK506-binding protein 5|54 kDa progesterone receptor-associated immunophilin|FF1 antigen|FK506-binding protein 5|HSP90-binding immunophilin|T-cell FK506-binding protein|peptidylprolyl cis-trans isomerase|rotamase; FK506 binding protein 5
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC37
  • P50CDC37
  • EG11140
    		•  The BioGRID Database Seperator CDC37 (cell division cycle 37, S. cerevisiae, homolog)|CDC37 cell division cycle 37 homolog|Hsp90 co-chaperone Cdc37|cell division cycle 37 protein; cell division cycle 37 homolog (S. cerevisiae)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SITPEC
  • ECSIT
  • EG51295
    		•  The BioGRID Database Seperator evolutionarily conserved signaling intermediate in Toll pathway|likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved|signaling intermediate in Toll pathway, evolutionarily conserved; ECSIT homolog (Drosophila)
    Gene Ontology: [View List]
    Invivo
    bait Kopp E (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSPCAL3
  • HSP90ALPHA
  • HSPCA
  • HSP90AA2
  • EG3324
    		•  The BioGRID Database Seperator heat shock protein 90kDa alpha (cytosolic), class A member 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Bouwmeester T (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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