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BioGRID | Network Layout for LYN for Homo sapiens
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LYN

 Homo sapiens
The BioGRID Database Seperator
Aliases: JTK8, FLJ26625, EG4067
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Yamaguchi sarcoma viral (v-yes-1) oncogene homolog|Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 11 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with LYN

LYN was identified with 89 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 CDC2
  • CDK1
  • DKFZp686L...
  • MGC111195
  • EG983
    		•  The BioGRID Database Seperator cell cycle controller CDC2|cell division control protein 2 homolog|cell division cycle 2 protein|cyclin-dependent kinase 1|p34 protein kinase; cell division cycle 2, G1 to S and G2 to M
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kharbanda S (1994)
    hit Pathan NI (1996)
    Biochemical Activity
    hit Kharbanda S (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP1R15A
  • GADD34
  • EG23645
    		•  The BioGRID Database Seperator growth arrest and DNA-damage-inducible 34|protein phosphatase 1, regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A
    Gene Ontology: [View List]
    Invivo
    hit Grishin AV (2001)
    Invitro
    hit Grishin AV (2001)
    Two-hybrid
    hit Grishin AV (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCAR1
  • CAS
  • CRKAS
  • P130Cas
  • EG9564
    		•  The BioGRID Database Seperator breast cancer anti-estrogen resistance 1; Crk-associated substrate p130Cas
    Gene Ontology: [View List]
    Invivo
    hit Qiu W (1998)
    Invitro
    hit Qiu W (1998)
    Affinity Capture-Western
    hit Manie SN (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOK1
  • P62DOK
  • MGC117395
  • MGC138860
  • EG1796
    		•  The BioGRID Database Seperator Downstream of tyrosine kinase 1|docking protein 1|docking protein 1 (downstream of tyrosine kinase 1)|docking protein 1, 62kD (downstream of tyrosine kinase 1); docking protein 1, 62kDa (downstream of tyrosine kinase 1)
    Gene Ontology: [View List]
    Biochemical Activity
    hit van Dijk TB (2000)
    Reconstituted Complex
    bait van Dijk TB (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYK
  • EG6850
    		•  The BioGRID Database Seperator spleen tyrosine kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sidorenko SP (1995)
    Reconstituted Complex
    bait Sidorenko SP (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MUC1
  • CD227
  • EMA
  • H23AG
  • EG4582
    		•  The BioGRID Database Seperator DF3 antigen|H23 antigen|MUC-1/SEC|MUC-1/X|MUC1 isoform T10|MUC1 isoform T11|MUC1 isoform T12|MUC1 isoform T13|MUC1/ZD|breast carcinoma-associated antigen DF3|episialin|mucin 1|mucin 1, transmembrane|peanut-reactive urinary mucin|polymorphic epithelial mucin|tumor associated epithelial mucin;...
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Li Y ()
    Affinity Capture-Western
    hit Li Y ()
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG2
  • EG5336
    		•  The BioGRID Database Seperator phospholipase C gamma 2|phospholipase C, gamma 2|phospholipase C, gamma 2 (phosphatidylyinositol-specific); phospholipase C, gamma 2 (phosphatidylinositol-specific)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Pleiman CM (1993)
    Reconstituted Complex
    hit Pleiman CM (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HCLS1
  • HS1
  • CTTNL
  • EG3059
    		•  The BioGRID Database Seperator hematopoietic cell-specific Lyn substrate 1; cortactin-like
    Gene Ontology: [View List]
    Invivo
    bait Yamanashi Y (1993)
    Invitro
    bait Yamanashi Y (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UNC119
  • HRG4
  • EG9094
    		•  The BioGRID Database Seperator retinal protein 4|unc119 (C.elegans) homolog; unc-119 homolog (C. elegans)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Cen O (2003)
    Affinity Capture-Western
    hit Cen O (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     INPP5D
  • SHIP
  • SHIP1
  • SIP-145
  • EG3635
    		•  The BioGRID Database Seperator SH2 containing inositol phosphatase|SH2 containing inositol phosphatase, isoform b|p150Ship|signaling inositol polyphosphate 5 phosphatase SIP-145; inositol polyphosphate-5-phosphatase, 145kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Baran CP (2003)
    Reconstituted Complex
    bait Baran CP (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BANK1
  • BANK
  • FLJ20706
  • FLJ34204
  • EG55024
    		•  The BioGRID Database Seperator B-cell scaffold protein with ankyrin repeats 1
    Gene Ontology: [View List]
    Invivo
    bait Yokoyama K (2002)
    Invitro
    bait Yokoyama K (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PECAM1
  • CD31
  • PECAM-1
  • EG5175
    		•  The BioGRID Database Seperator platelet/endothelial cell adhesion molecule (CD31 antigen); CD31/EndoCAM|PECAM-1, CD31/EndoCAM|adhesion molecule
    Gene Ontology: [View List]
    Invivo
    hit Cicmil M (2000)
    Invitro
    hit Cicmil M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCP2
  • SLP-76
  • SLP76
  • EG3937
    		•  The BioGRID Database Seperator 76 kDa tyrosine phosphoprotein|SH2 domain-containing leukocyte protein of 76kD|lymphocyte cytosolic protein 2|lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Gross BS (1999)
    Reconstituted Complex
    bait Gross BS (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRPV4
  • OTRPC4
  • TRP12
  • VRL-2
  • EG59341
    		•  The BioGRID Database Seperator OSM9-like transient receptor potential channel 4|osmosensitive transient receptor potential channel 4|transient receptor potential channel 12|vanilloid receptor-related osmotically activated channel; transient receptor potential cation channel, subfamily V, member 4
    Gene Ontology: [View List]
    Invivo
    bait Xu H (2003)
    Invitro
    bait Xu H (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEDD9
  • CAS-L
  • CASL
  • HEF1
  • EG4739
    		•  The BioGRID Database Seperator Crk-associated substrate related|cas-like docking|dJ49G10.2 (Enhancer of Filamentation 1 (HEF1))|dJ761I2.1 (enhancer of filamentation (HEF1))|enhancer of filamentation 1; neural precursor cell expressed, developmentally down-regulated 9
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Manie SN (1997)
    Affinity Capture-Western
    hit Manie SN (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPOR
  • MGC138358
  • EG2057
    		•  The BioGRID Database Seperator erythropoietin receptor
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Chin H (1998)
    Affinity Capture-Western
    bait/hit Chin H (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MS4A2
  • FCER1B
  • FCERI
  • MS4A1
  • EG2206
    		•  The BioGRID Database Seperator Fc IgE receptor, beta chain|Fc epsilon receptor I beta-chain|Fc-epsilon receptor I beta-chain|IgE responsiveness (atopic)|immunoglobulin E receptor, high affinity, beta polypeptide|membrane-spanning 4-domains, subfamily A, member 2; membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment...
    Gene Ontology: [View List]
    Invivo
    bait Paolini R (1995)
    bait Jouvin MH (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GP6
  • GPIV
  • GPVI
  • MGC138168
  • EG51206
    		•  The BioGRID Database Seperator platelet collagen receptor|platelet glycoprotein VI; glycoprotein VI (platelet)
    Gene Ontology: [View List]
    Invivo
    bait/hit Suzuki-Inoue K (2002)
    Invitro
    bait/hit Suzuki-Inoue K (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSF2RB
  • CD131
  • CDw131
  • IL3RB
  • EG1439
    		•  The BioGRID Database Seperator Colony-stimulating factor-2 receptor, beta, low-affinity|interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
    Gene Ontology: [View List]
    Invitro
    hit Adachi T (1999)
    Invivo
    hit Li Y (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTLA4
  • CD152
  • CTLA-4
  • CELIAC3
  • EG1493
    		•  The BioGRID Database Seperator cytotoxic T-lymphocyte-associated antigen 4|cytotoxic T-lymphocyte-associated serine esterase-4|ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; cytotoxic T-lymphocyte-associated protein 4
    Gene Ontology: [View List]
    Invivo
    bait Miyatake S (1998)
    Invitro
    bait Miyatake S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDK2
  • p33(CDK2)
  • EG1017
    		•  The BioGRID Database Seperator cdc2-related protein kinase|cell devision kinase 2|p33 protein kinase; cyclin-dependent kinase 2
    Gene Ontology: [View List]
    Invivo
    hit Mou S (1999)
    Invitro
    hit Mou S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIT
  • C-Kit
  • CD117
  • PBT
  • EG3815
    		•  The BioGRID Database Seperator mast/stem cell growth factor receptor|proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Invivo
    bait Linnekin D (1997)
    Invitro
    bait Linnekin D (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD22
  • SIGLEC-2
  • MGC130020
  • SIGLEC2
  • EG933
    		•  The BioGRID Database Seperator CD22 molecule; CD22 antigen
    Gene Ontology: [View List]
    Invitro
    bait Tuscano JM (1996)
    Biochemical Activity
    hit Poe JC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDE4A
  • DPDE2
  • PDE4
  • PDE46
  • EG5141
    		•  The BioGRID Database Seperator cAMP-specific phosphodiesterase|phosphodiesterase 4A, cAMP-specific|phosphodiesterase 4A, cAMP-specific (dunce|phosphodiesterase E2 dunce homolog, Drosophila|phosphodiesterase isozyme 4; phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit McPhee I (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRAM-1
  • MGC39864
  • PRAM1
  • EG84106
    		•  The BioGRID Database Seperator PML-RARA target gene encoding an Adaptor Molecule-1; PML-RARA regulated adaptor molecule 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Moog-Lutz C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN6
  • HCP
  • HCPH
  • HPTP1C
  • EG5777
    		•  The BioGRID Database Seperator 70 kda SHP-1L protein|hematopoietic cell phosphatase|hematopoietic cell protein-tyrosine phosphatase|protein-tyrosine phosphatase 1C; protein tyrosine phosphatase, non-receptor type 6
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Yoshida K (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KB2
  • KLS
  • P70-beta
  • P70-beta-1
  • EG6199
    		•  The BioGRID Database Seperator S6 kinase-related kinase|p70 ribosomal S6 kinase beta|ribosomal protein S6 kinase, 70kD, polypeptide 2|serine/threonine-protein kinase 14 beta; ribosomal protein S6 kinase, 70kDa, polypeptide 2
    Gene Ontology: [View List]
    Biochemical Activity
    hit Rebholz H (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KB1
  • PS6K
  • S6K
  • S6K1
  • EG6198
    		•  The BioGRID Database Seperator p70 S6 kinase, alpha 1|p70 S6 kinase, alpha 2|ribosomal protein S6 kinase, 70kD, polypeptide 1|serine/threonine kinase 14 alpha; ribosomal protein S6 kinase, 70kDa, polypeptide 1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Rebholz H (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCAP2
  • MGC10411
  • MGC33304
  • PRAP
  • EG8935
    		•  The BioGRID Database Seperator Fyn-associated phosphoprotein SKAP55 homologue|Pyk2/RAFTK-associated protein|src family associated phosphoprotein 2|src kinase-associated phosphoprotein of 55-related protein|src-associated adaptor protein; src kinase associated phosphoprotein 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Kouroku Y (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MME
  • CALLA
  • CD10
  • NEP
  • EG4311
    		•  The BioGRID Database Seperator atriopeptidase|common acute lymphocytic leukemia antigen|enkephalinase|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)|neprilysin|neutral endopeptidase; membrane metallo-endopeptidase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ganju RK (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAB3
  • EG139716
    		•  The BioGRID Database Seperator DOS/Gab family member 3|Gab3 protein|Gab3 scaffolding protein; GRB2-associated binding protein 3
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Wolf I (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK3
  • ERK1
  • P44ERK1
  • P44MAPK
  • EG5595
    		•  The BioGRID Database Seperator extracellular signal-regulated kinase 1|extracellular signal-related kinase 1; mitogen-activated protein kinase 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Wei S (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD36
  • FAT
  • GP3B
  • GP4
  • EG948
    		•  The BioGRID Database Seperator CD36 antigen|CD36 antigen (collagen type I receptor, thrombospondin receptor)|PAS-4 protein|cluster determinant 36|collagen type I receptor|fatty acid translocase|glycoprotein IIIb|leukocyte differentiation antigen CD36|platelet collagen receptor|platelet glycoprotein IV|scavenger receptor...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Huang MM (1991)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK2
  • EG3717
    		•  The BioGRID Database Seperator Janus kinase 2|OTTHUMP00000043260|tyrosine-protein kinase JAK2; Janus kinase 2 (a protein tyrosine kinase)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Chin H (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TEC
  • PSCTK4
  • MGC126760
  • MGC126762
  • EG7006
    		•  The BioGRID Database Seperator tec protein tyrosine kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait van Dijk TB (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Protein-peptide
    bait Pirozzi G (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2B
  • CADTK
  • CAKB
  • FADK2
  • EG2185
    		•  The BioGRID Database Seperator CAK beta|calcium-dependent tyrosine kinase|cell adhesion kinase beta|focal adhesion kinase 2|proline-rich tyrosine kinase 2|protein kinase B|protein tyrosine kinase 2 beta|related adhesion focal tyrosine kinase; PTK2B protein tyrosine kinase 2 beta
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yamasaki M (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAB2
  • KIAA0571
  • EG9846
    		•  The BioGRID Database Seperator GRB2-associated binding protein 2; Grb2-associated binder 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Xie ZH (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAG1
  • CBP
  • FLJ37858
  • PAG
  • EG55824
    		•  The BioGRID Database Seperator Csk-binding protein|phosphoprotein associated with glycosphingolipid-enriched microdomains; phosphoprotein associated with glycosphingolipid microdomains 1
    Gene Ontology: [View List]
    Invitro
    bait Brdicka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHC1
  • FLJ26504
  • SHC
  • SHCA
  • EG6464
    		•  The BioGRID Database Seperator SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1
    Gene Ontology: [View List]
    Invitro
    hit Ptasznik A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TYK2
  • JTK1
  • EG7297
    		•  The BioGRID Database Seperator tyrosine kinase 2
    Gene Ontology: [View List]
    Invitro
    hit Uddin S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKDC
  • DNAPK
  • DNPK1
  • HYRC
  • EG5591
    		•  The BioGRID Database Seperator hyper-radiosensitivity of murine scid mutation, complementing 1; protein kinase, DNA-activated, catalytic polypeptide
    Gene Ontology: [View List]
    Invitro
    bait Kumar S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GALNAC4S-6ST
  • BRAG
  • DKFZp781H...
  • KIAA0598
  • EG51363
    		•  The BioGRID Database Seperator B cell RAG associated protein (GALNAC4S-6ST)|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; B cell RAG associated protein
    Gene Ontology: [View List]
    Invivo
    bait Verkoczy LK (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG1
  • PLC-II
  • PLC1
  • PLC148
  • EG5335
    		•  The BioGRID Database Seperator 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phosphol...
    Gene Ontology: [View List]
    Invivo
    bait Perez-Villar JJ (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSF1R
  • C-FMS
  • CD115
  • CSFR
  • EG1436
    		•  The BioGRID Database Seperator CD115 antigen|FMS proto-oncogene|colony stimulating factor 1 receptor|macrophage colony stimulating factor I receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog
    Gene Ontology: [View List]
    Invivo
    hit Li Y (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator