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BioGRID | Network Layout for JAK1 for Homo sapiens
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JAK1

 Homo sapiens
The BioGRID Database Seperator
Aliases: JAK1A, JAK1B, EG3716
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Janus kinase 1 (a protein tyrosine kinase); janus kinase 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 3 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with JAK1

JAK1 was identified with 67 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Invivo
    hit Carter-Su C (2000)
    Reconstituted Complex
    bait Yin T (1997)
    Biochemical Activity
    hit Yin T (1997)
    Affinity Capture-Western
    bait Lehmann U (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL6ST
  • CD130
  • CDw130
  • GP130
  • EG3572
    		•  The BioGRID Database Seperator CD130 antigen|IL6ST nirs variant 3|gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form|gp130 transducer chain|interleukin 6 signal transducer|interleukin receptor beta chain|membrane glycoprotein gp130|oncostatin M receptor; interleukin 6 signal transducer (gp130, oncostatin...
    Gene Ontology: [View List]
    Invivo
    hit Haan C (2002)
    Invitro
    hit Haan C (2002)
    Affinity Capture-Western
    hit Haan C (2001)
    Reconstituted Complex
    hit Haan C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF1A
  • CD120a
  • FPF
  • MGC19588
  • EG7132
    		•  The BioGRID Database Seperator tumor necrosis factor binding protein 1|tumor necrosis factor receptor 1|tumor necrosis factor receptor type 1|tumor necrosis factor-alpha receptor; tumor necrosis factor receptor superfamily, member 1A
    Gene Ontology: [View List]
    Invitro
    hit Miscia S (2002)
    Invivo
    hit Miscia S (2002)
    Reconstituted Complex
    bait Guo D (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL2RB
  • P70-75
  • CD122
  • EG3560
    		•  The BioGRID Database Seperator CD122 antigen|OTTHUMP00000028799|high affinity IL-2 receptor beta subunit|interleukin 2 receptor beta; interleukin 2 receptor, beta
    Gene Ontology: [View List]
    Invivo
    hit Usacheva A (2002)
    Affinity Capture-Western
    hit Miyazaki T (1994)
    hit Russell SM (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT5A
  • MGF
  • STAT5
  • EG6776
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 5A
    Gene Ontology: [View List]
    Two-hybrid
    hit Fujitani Y (1997)
    Affinity Capture-Western
    bait/hit Fujitani Y (1997)
    Reconstituted Complex
    hit Fujitani Y (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL10RA
  • CDW210A
  • HIL-10R
  • IL-10R1
  • EG3587
    		•  The BioGRID Database Seperator interleukin 10 receptor, alpha
    Gene Ontology: [View List]
    Invivo
    hit Usacheva A (2002)
    Invitro
    hit Usacheva A (2002)
    Reconstituted Complex
    bait Usacheva A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STATIP1
  • ELP2
  • FLJ10879
  • SHINC-2
  • EG55250
    		•  The BioGRID Database Seperator elongator protein 2|signal transducer and activator of transcription 3 interacting protein 1|signal transducer and activator of transcription interacting protein 1; elongation protein 2 homolog (S. cerevisiae)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Collum RG (2000)
    Reconstituted Complex
    bait Collum RG (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSHR
  • LGR3
  • MGC75129
  • hTSHR-I
  • EG7253
    		•  The BioGRID Database Seperator seven transmembrane helix receptor|thyroid stimulating hormone receptor, isoform 2|thyrotropin receptor|thyrotropin receptor-I, hTSHR-I; thyroid stimulating hormone receptor
    Gene Ontology: [View List]
    Invivo
    hit Park ES (2000)
    Invitro
    hit Park ES (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT3
  • APRF
  • FLJ20882
  • MGC16063
  • EG6774
    		•  The BioGRID Database Seperator DNA-binding protein APRF|acute-phase response factor|signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Ueda T (2002)
    Affinity Capture-Western
    hit Spiekermann K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT5B
  • STAT5
  • EG6777
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 5B; transcription factor STAT5B
    Gene Ontology: [View List]
    Two-hybrid
    hit Fujitani Y (1997)
    Affinity Capture-Western
    bait/hit Fujitani Y (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS1
  • HIRS-1
  • EG3667
    		•  The BioGRID Database Seperator insulin receptor substrate 1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Gual P (1998)
    Affinity Capture-Western
    bait Johnston JA (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GNB2L1
  • Gnb2-rs1
  • H12.3
  • HLC-7
  • EG10399
    		•  The BioGRID Database Seperator lung cancer oncogene 7|proliferation-inducing gene 21|protein homologous to chicken B complex protein, guanine nucleotide binding; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Usacheva A (2003)
    Reconstituted Complex
    bait Usacheva A (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAM2
  • DKFZp564C...
  • Hbp
  • STAM2A
  • EG10254
    		•  The BioGRID Database Seperator STAM-like protein containing SH3 and ITAM domains 2|signal transducing adaptor molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
    Gene Ontology: [View List]
    Invitro
    hit Endo K (2000)
    Biochemical Activity
    hit Pandey A (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL4R
  • CD124
  • IL4RA
  • EG3566
    		•  The BioGRID Database Seperator interleukin 4 receptor alpha chain|interleukin-4 receptor alpha chain; interleukin 4 receptor
    Gene Ontology: [View List]
    Invivo
    bait Usacheva A (2002)
    Invitro
    bait Usacheva A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GHR
  • GHBP
  • EG2690
    		•  The BioGRID Database Seperator growth hormone binding protein|serum binding protein|somatotropin receptor; growth hormone receptor
    Gene Ontology: [View List]
    Invivo
    hit Hellgren G (1999)
    Invitro
    hit Hellgren G (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Invivo
    hit Giorgetti-Peraldi S (1995)
    Affinity Capture-Western
    hit Kim H (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TYK2
  • JTK1
  • EG7297
    		•  The BioGRID Database Seperator tyrosine kinase 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Domanski P (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IGF1R
  • JTK13
  • CD221
  • IGFIR
  • EG3480
    		•  The BioGRID Database Seperator insulin-like growth factor 1 receptor; clone 1900 unknown protein
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Gual P (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLAUR
  • CD87
  • UPAR
  • URKR
  • EG5329
    		•  The BioGRID Database Seperator monocyte activation antigen Mo3|u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Dumler I (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRCA1
  • BRCAI
  • IRIS
  • PSCP
  • EG672
    		•  The BioGRID Database Seperator BRCA1/BRCA2-containing complex, subunit 1|breast and ovarian cancer susceptibility protein 1; breast cancer 1, early onset
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Gao B (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL9R
  • CD129
  • EG3581
    		•  The BioGRID Database Seperator interleukin 9 receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Demoulin JB (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL21R
  • MGC10967
  • NILR
  • EG50615
    		•  The BioGRID Database Seperator interleukin 21 receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ozaki K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSF3R
  • CD114
  • GCSFR
  • EG1441
    		•  The BioGRID Database Seperator CD114 antigen|colony stimulating factor 3 receptor|granulocyte colony stimulating factor receptor; colony stimulating factor 3 receptor (granulocyte)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nicholson SE (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL5RA
  • CDw125
  • HSIL5R3
  • IL5R
  • EG3568
    		•  The BioGRID Database Seperator CD125 antigen|interleukin 5 receptor type 3|interleukin-5 receptor alpha chain|interleukin-5 receptor alpha subunit; interleukin 5 receptor, alpha
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ogata N (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS2
  • EG8660
    		•  The BioGRID Database Seperator insulin receptor substrate 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Johnston JA (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BTK
  • AGMX1
  • AT
  • ATK
  • RP1-164F3.2
    		•  The BioGRID Database Seperator Bruton's tyrosine kinase|OTTHUMP00000063593|dominant-negative kinase-deficient Brutons tyrosine kinase|tyrosine-protein kinase BTK; Bruton agammaglobulinemia tyrosine kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Takahashi-Tezuka M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN6
  • HCP
  • HCPH
  • HPTP1C
  • EG5777
    		•  The BioGRID Database Seperator 70 kda SHP-1L protein|hematopoietic cell phosphatase|hematopoietic cell protein-tyrosine phosphatase|protein-tyrosine phosphatase 1C; protein tyrosine phosphatase, non-receptor type 6
    Gene Ontology: [View List]
    Biochemical Activity
    bait Yetter A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABL2
  • ABLL
  • ARG
  • FLJ22224
  • RP11-177A...
    		•  The BioGRID Database Seperator Abelson murine leukemia viral (v-abl) oncogene homolog 2|Abelson-related|v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Danial NN (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK3
  • JAK-3
  • JAK3_HUMAN
  • JAKL
  • EG3718
    		•  The BioGRID Database Seperator Janus kinase 3|leukocyte Janus kinase|tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte)
    Gene Ontology: [View List]
    Invivo
    hit Zhu MH (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATIC
  • AICAR
  • AICARFT
  • IMPCHASE
  • EG471
    		•  The BioGRID Database Seperator 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; AICARFT/IMPCHASE
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OSMR
  • MGC75127
  • OSMRB
  • MGC150626
  • EG9180
    		•  The BioGRID Database Seperator oncostatin M receptor
    Gene Ontology: [View List]
    Invivo
    hit Hermanns HM (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYK
  • EG6850
    		•  The BioGRID Database Seperator spleen tyrosine kinase
    Gene Ontology: [View List]
    Invitro
    bait Zhou YJ (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R1
  • GRB1
  • p85-ALPHA
  • EG5295
    		•  The BioGRID Database Seperator phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit, polypeptide 1|phosphoinositide-3-kinase, regulatory subunit, polypeptide...
    Gene Ontology: [View List]
    Invivo
    hit Migone TS (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    hit Sakatsume M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARRB1
  • ARB1
  • ARR1
  • EG408
    		•  The BioGRID Database Seperator arrestin, beta 1; arrestin beta 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELF3
  • EPR-1
  • ERT
  • ESE-1
  • EG1999
    		•  The BioGRID Database Seperator E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific)|E74-like factor 3 (ets domain transcription factor)|epithelial-restricted with serine box|epithelium-restricted Ets protein ESX|ets domain transcription factor, serine box (epithelial-specific); E74-like factor...
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHB
  • RP11-3J10.8
  • bA3J10.2
  • RP11-3J10.3
    		•  The BioGRID Database Seperator SHB (Src homology 2 domain containing) adaptor protein B|SHB adaptor protein (a Src homology 2 protein); Src homology 2 domain containing adaptor protein B
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Lindholm CK (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2B
  • CADTK
  • CAKB
  • FADK2
  • EG2185
    		•  The BioGRID Database Seperator CAK beta|calcium-dependent tyrosine kinase|cell adhesion kinase beta|focal adhesion kinase 2|proline-rich tyrosine kinase 2|protein kinase B|protein tyrosine kinase 2 beta|related adhesion focal tyrosine kinase; PTK2B protein tyrosine kinase 2 beta
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Benbernou N (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SKB1
  • IBP72
  • JBP1
  • PRMT5
  • EG10419
    		•  The BioGRID Database Seperator HMT1 hnRNP methyltransferase-like 5|SKB1 (S. cerevisiae) homolog|SKB1 homolog|skb1 (S. pombe) homolog; protein arginine methyltransferase 5
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Pollack BP (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator