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BioGRID | Network Layout for INSR for Homo sapiens
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INSR

 Homo sapiens
The BioGRID Database Seperator
Aliases: CD220, HHF5, EG3643
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: insulin receptor
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 19 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with INSR

INSR was identified with 69 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 GRB10
  • GRB-IR
  • IRBP
  • KIAA0207
  • EG2887
    		•  The BioGRID Database Seperator GRB10 adaptor protein|maternally expressed gene 1; growth factor receptor-bound protein 10
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Langlais P (2000)
    bait Hansen H (1996)
    bait Liu F (1995)
    Two-hybrid
    hit Hansen H (1996)
    hit Liu F (1995)
    hit He W (1998)
    Reconstituted Complex
    bait Hansen H (1996)
    bait Liu F (1995)
    bait He W (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH2B
  • DKFZp547G...
  • SH2-B
  • SH2B1
  • EG25970
    		•  The BioGRID Database Seperator SH2 domain-containing putative adapter SH2-B|SH2-B alpha signaling protein|SH2-B gamma signaling protein|SH2-B homolog; SH2B adaptor protein 1
    Gene Ontology: [View List]
    Invivo
    bait Kotani K (1998)
    bait Nelms K (1999)
    Invitro
    bait Nelms K (1999)
    Affinity Capture-Western
    hit Kotani K (1998)
    Two-hybrid
    hit Kotani K (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Invivo
    hit Kharitonenkov A (1995)
    Invitro
    hit Kharitonenkov A (1995)
    Reconstituted Complex
    hit Maegawa H (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMAD2
  • JV18
  • JV18-1
  • MADH2
  • EG4087
    		•  The BioGRID Database Seperator MAD, mothers against decapentaplegic homolog 2|Mad protein homolog|Mad, mothers against decapentaplegic homolog 2|Mad-related protein 2|SMAD, mothers against DPP homolog 2|Sma- and Mad-related protein 2|mother against DPP homolog 2; SMAD family member 2
    Gene Ontology: [View List]
    Two-hybrid
    bait O'Neill TJ (1997)
    Affinity Capture-Western
    bait O'Neill TJ (1997)
    Reconstituted Complex
    bait O'Neill TJ (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOCS3
  • CIS3
  • Cish3
  • MGC71791
  • EG9021
    		•  The BioGRID Database Seperator STAT induced STAT inhibitor 3|cytokine-induced SH2 protein 3; suppressor of cytokine signaling 3
    Gene Ontology: [View List]
    Invitro
    hit Dey BR (2000)
    Two-hybrid
    hit Dey BR (2000)
    Affinity Capture-Western
    hit Senn JJ (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB7
  • EG2886
    		•  The BioGRID Database Seperator growth factor receptor-bound protein 7
    Gene Ontology: [View List]
    Invivo
    hit Kasus-Jacobi A (2000)
    Invitro
    hit Kasus-Jacobi A (2000)
    Two-hybrid
    hit Kasus-Jacobi A (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB14
  • EG2888
    		•  The BioGRID Database Seperator growth factor receptor-bound protein 14
    Gene Ontology: [View List]
    Invivo
    bait Bereziat V (2002)
    Invitro
    bait Bereziat V (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCD
  • MAY1
  • MGC49908
  • nPKC-delta
  • EG5580
    		•  The BioGRID Database Seperator protein kinase C, delta
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Braiman L (2001)
    bait Rosenzweig T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ENPP1
  • M6S1
  • NPP1
  • NPPS
  • EG5167
    		•  The BioGRID Database Seperator Ly-41 antigen|OTTHUMP00000043194|alkaline phosphodiesterase 1|membrane component, chromosome 6, surface marker 1|phosphodiesterase I/nucleotide pyrophosphatase 1|plasma-cell membrane glycoprotein 1; ectonucleotide pyrophosphatase/phosphodiesterase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Maddux BA (2000)
    Reconstituted Complex
    hit Maddux BA (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPRF
  • LAR
  • FLJ43335
  • FLJ45062
  • EG5792
    		•  The BioGRID Database Seperator LCA-homolog|leukocyte antigen-related (LAR) PTP receptor|leukocyte antigen-related tyrosine phosphatase|protein tyrosine phosphatase, receptor type, F polypeptide|receptor-linked protein-tyrosine phosphatase LAR; protein tyrosine phosphatase, receptor type, F
    Gene Ontology: [View List]
    Invivo
    hit Hashimoto N (1992)
    Invitro
    bait Hashimoto N (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV1
  • VAV
  • EG7409
    		•  The BioGRID Database Seperator oncogene vav|vav 1 oncogene|vav proto-oncogene; vav 1 guanine nucleotide exchange factor
    Gene Ontology: [View List]
    Invivo
    hit Uddin S (1995)
    Invitro
    hit Uddin S (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R3
  • DKFZp686P...
  • p55-GAMMA
  • FLJ41892
  • EG8503
    		•  The BioGRID Database Seperator 100% homology to SWISS-PROT Q92569|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)
    Gene Ontology: [View List]
    Invitro
    hit Dey BR (1998)
    Two-hybrid
    hit Dey BR (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNX2
  • MGC5204
  • TRG-9
  • EG6643
    		•  The BioGRID Database Seperator sorting nexin 2
    Gene Ontology: [View List]
    Invivo
    bait/hit Haft CR (1998)
    Invitro
    bait/hit Haft CR (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SORBS1
  • CAP
  • DKFZp586P...
  • FLAF2
  • EG10580
    		•  The BioGRID Database Seperator Fas-ligand associated factor 2|SH3-domain protein 5 (ponsin)|c-Cbl associated protein|ponsin; sorbin and SH3 domain containing 1
    Gene Ontology: [View List]
    Invivo
    hit Lin WH (2001)
    Invitro
    hit Lin WH (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNX6
  • MGC3157
  • MSTP010
  • TFAF2
  • EG58533
    		•  The BioGRID Database Seperator tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2; sorting nexin 6
    Gene Ontology: [View List]
    Invivo
    bait Parks WT (2001)
    Invitro
    bait Parks WT (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RASA1
  • CMAVM
  • DKFZp434N...
  • GAP
  • EG5921
    		•  The BioGRID Database Seperator GTPase activating protein|RAS p21 protein activator 1|triphosphatase-activating protein; RAS p21 protein activator (GTPase activating protein) 1
    Gene Ontology: [View List]
    Invivo
    hit Pronk GJ (1992)
    Invitro
    hit Pronk GJ (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS1
  • HIRS-1
  • EG3667
    		•  The BioGRID Database Seperator insulin receptor substrate 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Aguirre V (2002)
    hit Sawka-Verhelle D (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HRAS
  • HRAS1
  • K-ras
  • N-ras
  • EG3265
    		•  The BioGRID Database Seperator H-RasIDX|c-has/bas p21 protein|c-ras-Ki-2 protein|p21 protein; v-Ha-ras Harvey rat sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Biochemical Activity
    bait O'Brien RM (1987)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN6
  • HCP
  • HCPH
  • HPTP1C
  • EG5777
    		•  The BioGRID Database Seperator 70 kda SHP-1L protein|hematopoietic cell phosphatase|hematopoietic cell protein-tyrosine phosphatase|protein-tyrosine phosphatase 1C; protein tyrosine phosphatase, non-receptor type 6
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Uchida T (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Grb14
  • EG58844
    		•  The BioGRID Database Seperator growth factor receptor bound protein 14
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Kasus-Jacobi A (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IGF2
  • FLJ44734
  • INSIGF
  • C11orf43
  • EG3481
    		•  The BioGRID Database Seperator insulin-like growth factor 2|insulin-like growth factor II|insulin-like growth factor type 2|putative insulin-like growth factor II associated protein|somatomedin A; insulin-like growth factor 2 (somatomedin A)
    Gene Ontology: [View List]
    Invivo
    hit O'Dell SD (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     INSRR
  • IRR
  • EG3645
    		•  The BioGRID Database Seperator insulin receptor-related receptor; IR-related receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Jui HY (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV3
  • FLJ40431
  • EG10451
    		•  The BioGRID Database Seperator vav 3 guanine nucleotide exchange factor; vav 3 oncogene
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Zeng L (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KHDRBS1
  • Sam68
  • p62
  • FLJ34027
  • EG10657
    		•  The BioGRID Database Seperator KH domain containing, RNA binding, signal transduction associated 1; GAP-associated tyrosine phosphoprotein p62 (Sam68)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Sanchez-Margalet V (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ishihara H (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAV1
  • CAV
  • MSTP085
  • VIP21
  • EG857
    		•  The BioGRID Database Seperator caveolae protein, 22-kD|caveolin 1|caveolin 1 caveolae protein, 22kD|caveolin 1, alpha isoform|caveolin 1, beta isoform|cell growth-inhibiting protein 32; caveolin 1, caveolae protein, 22kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Nystrom FH (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK1
  • ERK
  • ERK2
  • ERT1
  • EG5594
    		•  The BioGRID Database Seperator extracellular signal-regulated kinase 2|extracellular signal-regulated kinase-2|mitogen-activated protein kinase 2|protein tyrosine kinase ERK2; mitogen-activated protein kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Lin YL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSK
  • MGC117393
  • EG1445
    		•  The BioGRID Database Seperator c-src tyrosine kinase
    Gene Ontology: [View List]
    Two-hybrid
    bait Arbet-Engels C (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNX1
  • HsT17379
  • MGC8664
  • SNX1A
  • EG6642
    		•  The BioGRID Database Seperator sorting nexin 1A; sorting nexin 1
    Gene Ontology: [View List]
    Invivo
    bait Haft CR (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN1
  • PTP1B
  • EG5770
    		•  The BioGRID Database Seperator non-receptor tyrosine phosphatase 1|protein tyrosine phosphatase 1B|protein tyrosine phosphatase, placental; protein tyrosine phosphatase, non-receptor type 1
    Gene Ontology: [View List]
    Invitro
    hit Seely BL (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYNCRIP
  • GRY-RBP
  • NSAP1
  • RP1-3J17.2
  • EG10492
    		•  The BioGRID Database Seperator NS1-associated protein 1|heterogeneous nuclear ribonucleoprotein Q; synaptotagmin binding, cytoplasmic RNA interacting protein
    Gene Ontology: [View List]
    Invitro
    bait Hresko RC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNX4
  • EG8723
    		•  The BioGRID Database Seperator sorting nexin 4
    Gene Ontology: [View List]
    Invivo
    hit Haft CR (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAB1
  • EG2549
    		•  The BioGRID Database Seperator GRB2-associated binding protein 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Rocchi S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK3
  • ERK1
  • P44ERK1
  • P44MAPK
  • EG5595
    		•  The BioGRID Database Seperator extracellular signal-regulated kinase 1|extracellular signal-related kinase 1; mitogen-activated protein kinase 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Lin YL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN12
  • PTP-PEST
  • PTPG1
  • tcag7.1075
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 12; protein-tyrosine phosphatase G1
    Gene Ontology: [View List]
    Invitro
    bait Yang Q (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS2
  • EG8660
    		•  The BioGRID Database Seperator insulin receptor substrate 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Sawka-Verhelle D (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FRS2
  • FRS2A
  • FRS2alpha
  • SNT
  • EG10818
    		•  The BioGRID Database Seperator FGFR signalling adaptor|suc1-associated neurotrophic factor target; fibroblast growth factor receptor substrate 2
    Gene Ontology: [View List]
    Biochemical Activity
    hit Delahaye L (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AHSG
  • AHS
  • FETUA
  • HSGA
  • EG197
    		•  The BioGRID Database Seperator Alpha-2HS-glycoprotein|fetuin-A; alpha-2-HS-glycoprotein
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Srinivas PR (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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