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GZMB
Homo sapiens
Aliases:
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT, EG3002
Description:
T-cell serine protease 1-3E|cathepsin G-like 1|cytotoxic serine protease B|fragmentin 2|granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
7 total GO mappings for this record.
[view list]
Function
Process
Component
•
protein binding
(
IPI
)
•
granzyme B activity
(
TAS
)
•
cleavage of lamin
(
IDA
)
•
apoptosis
(
TAS
)
•
immunological synapse
(
TAS
)
•
nucleus
(
TAS
)
•
cytoplasm
(
NR
)
Download interactions associated with GZMB
GZMB was identified with
6
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
CHRM3
HM3
EG1131
m3 muscarinic receptor|muscarinic acetylcholine receptor M3; cholinergic receptor, muscarinic 3
Gene Ontology:
[View List]
Invitro
hit
Nagaraju K (2001)
Invivo
hit
Nagaraju K (2001)
RAB27A
GS2
HsT18676
RAB27
EG5873
GTP-binding protein Ram|Ras-related protein Rab-27A; RAB27A, member RAS oncogene family
Gene Ontology:
[View List]
Invivo
hit
Haddad EK (2001)
PRF1
HPLH2
MGC65093
P1
RP11-710A...
cytolysin|lymphocyte pore forming protein|perforin 1; perforin 1 (pore forming protein)
Gene Ontology:
[View List]
Invivo
hit
Trapani JA (1995)
PRG1
FLJ12930
MGC9289
PPG
EG5552
hematopoetic proteoglycan core peptide|platelet proteoglycan protein core|proteoglycan 1, secretory granule|proteoglycan protein core for mast cell secretory granule|secretory granule proteoglycan 1|secretory granule proteoglycan core peptide|serglycin proteoglycan; serglycin
Gene Ontology:
[View List]
Invitro
hit
Raja SM (2002)
SERPINB9
CAP-3
CAP3
PI9
EG5272
protease inhibitor 9 (ovalbumin type)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9; serpin peptidase inhibitor, clade B (ovalbumin), member 9
Gene Ontology:
[View List]
Invitro
hit
Sun J (1996)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.