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BioGRID | Network Layout for GRB10 for Homo sapiens
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GRB10

 Homo sapiens
The BioGRID Database Seperator
Aliases: GRB-IR, IRBP, KIAA0207, MEG1, RSS, Grb-10, EG2887
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: GRB10 adaptor protein|maternally expressed gene 1; growth factor receptor-bound protein 10
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with GRB10

GRB10 was identified with 52 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 INSR
  • CD220
  • HHF5
  • EG3643
    		•  The BioGRID Database Seperator insulin receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Langlais P (2000)
    hit Hansen H (1996)
    hit Liu F (1995)
    Two-hybrid
    bait Hansen H (1996)
    bait Liu F (1995)
    bait He W (1998)
    Reconstituted Complex
    hit Hansen H (1996)
    hit Liu F (1995)
    hit He W (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    hit Nantel A (1998)
    Invitro
    hit Nantel A (1998)
    Two-hybrid
    hit Nantel A (1998)
    bait Nantel A (1999)
    Co-fractionation
    hit Nantel A (1999)
    Affinity Capture-Western
    bait Nantel A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IGF1R
  • JTK13
  • CD221
  • IGFIR
  • EG3480
    		•  The BioGRID Database Seperator insulin-like growth factor 1 receptor; clone 1900 unknown protein
    Gene Ontology: [View List]
    Invivo
    hit Morrione A (1996)
    Invitro
    hit Morrione A (1996)
    Two-hybrid
    hit Morrione A (1996)
    bait Dey BR (1996)
    Affinity Capture-Western
    bait/hit Vecchione A (2003)
    Reconstituted Complex
    hit He W (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCR
  • ALL
  • BCR1
  • CML
  • EG613
    		•  The BioGRID Database Seperator breakpoint cluster region protein; breakpoint cluster region
    Gene Ontology: [View List]
    Invivo
    hit Bai RY (1998)
    Invitro
    hit Bai RY (1998)
    Two-hybrid
    bait Bai RY (1998)
    Affinity Capture-Western
    bait Bai RY (1998)
    Reconstituted Complex
    bait Bai RY (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIT
  • C-Kit
  • CD117
  • PBT
  • EG3815
    		•  The BioGRID Database Seperator mast/stem cell growth factor receptor|proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Invivo
    hit Jahn T (2002)
    Invitro
    hit Jahn T (2002)
    Two-hybrid
    hit Jahn T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Invivo
    hit Frantz JD (1997)
    Invitro
    hit Frantz JD (1997)
    Reconstituted Complex
    hit He W (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K1
  • MAPKK1
  • MEK1
  • MKK1
  • EG5604
    		•  The BioGRID Database Seperator protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); mitogen-activated protein kinase kinase 1
    Gene Ontology: [View List]
    Invivo
    hit Nantel A (1998)
    Invitro
    hit Nantel A (1998)
    Two-hybrid
    hit Nantel A (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RET
  • CDHF12
  • HSCR1
  • MEN2A
  • EG5979
    		•  The BioGRID Database Seperator Hirschsprung disease 1|RET transforming sequence|cadherin family member 12|hydroxyaryl-protein kinase|multiple endocrine neoplasia and medullary thyroid carcinoma 1|oncogene RET|receptor tyrosine kinase|ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung...
    Gene Ontology: [View List]
    Invivo
    hit Pandey A (1995)
    Invitro
    hit Pandey A (1995)
    Two-hybrid
    hit Pandey A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PERQ1
  • GIGYF1
  • EG64599
    		•  The BioGRID Database Seperator Grb10 interacting GYF protein 1|postmeiotic segregation increased 2-like 12; PERQ amino acid rich, with GYF domain 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Giovannone B (2003)
    Affinity Capture-Western
    hit Giovannone B (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK2
  • EG3717
    		•  The BioGRID Database Seperator Janus kinase 2|OTTHUMP00000043260|tyrosine-protein kinase JAK2; Janus kinase 2 (a protein tyrosine kinase)
    Gene Ontology: [View List]
    Invivo
    bait Moutoussamy S (1998)
    Invitro
    bait Moutoussamy S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KDR
  • FLK1
  • VEGFR
  • VEGFR2
  • EG3791
    		•  The BioGRID Database Seperator kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Giorgetti-Peraldi S (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Biochemical Activity
    bait Langlais P (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FYN
  • MGC45350
  • SLK
  • SYN
  • RP1-66H14.1
    		•  The BioGRID Database Seperator OKT3-induced calcium influx regulator|c-syn protooncogene|protein-tyrosine kinase fyn|proto-oncogene tyrosine-protein kinase fyn|src-like kinase|src/yes-related novel|tyrosine kinase p59fyn(T); FYN oncogene related to SRC, FGR, YES
    Gene Ontology: [View List]
    Biochemical Activity
    bait Langlais P (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS1
  • HIRS-1
  • EG3667
    		•  The BioGRID Database Seperator insulin receptor substrate 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Hansen H (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABL1
  • ABL
  • JTK7
  • c-ABL
  • RP11-83J2...
    		•  The BioGRID Database Seperator Abelson murine leukemia viral (v-abl) oncogene homolog 1|BCR/ABL fusion protein|bcr/c-abl oncogene protein|proto-oncogene tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Bai RY (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDGFRB
  • CD140B
  • JTK12
  • PDGF-R-beta
  • EG5159
    		•  The BioGRID Database Seperator beta platelet-derived growth factor receptor|platelet-derived growth factor receptor beta; platelet-derived growth factor receptor, beta polypeptide
    Gene Ontology: [View List]
    Invitro
    hit Frantz JD (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AKT1
  • MGC99656
  • PKB
  • PRKBA
  • EG207
    		•  The BioGRID Database Seperator RAC-alpha serine/threonine-protein kinase|murine thymoma viral (v-akt) oncogene homolog-1|protein kinase B|rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    hit Jahn T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELK1
  • EG2002
    		•  The BioGRID Database Seperator ELK1, member of ETS oncogene family; ELK1 protein
    Gene Ontology: [View List]
    Invivo
    bait Stein E (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GHR
  • GHBP
  • EG2690
    		•  The BioGRID Database Seperator growth hormone binding protein|serum binding protein|somatotropin receptor; growth hormone receptor
    Gene Ontology: [View List]
    Invivo
    bait Moutoussamy S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNRC15
  • GIGYF2
  • KIAA0642
  • DKFZp686I...
  • EG26058
    		•  The BioGRID Database Seperator Grb10 interacting GYF protein 2|PERQ amino acid rich, with GYF domain 2|PERQ amino acid rich, with GYF domain 3; trinucleotide repeat containing 15
    Gene Ontology: [View List]
    Two-hybrid
    hit Giovannone B (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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