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BioGRID | Network Layout for GRB2 for Homo sapiens
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GRB2

 Homo sapiens
The BioGRID Database Seperator
Aliases: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, EG2885
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 9 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with GRB2

GRB2 was identified with 420 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 CBL
  • C-CBL
  • CBL2
  • RNF55
  • EG867
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence; oncogene CBL2
    Gene Ontology: [View List]
    Invivo
    hit Saci A (2002)
    hit Odai H (1997)
    hit Husson H (1997)
    Invitro
    hit Saci A (2002)
    hit Odai H (1997)
    hit Husson H (1997)
    Two-hybrid
    hit Saci A (2002)
    hit Odai H (1997)
    hit Husson H (1997)
    Affinity Capture-Western
    bait Jain SK (1997)
    bait Ettenberg SA (1999)
    bait Wong A (2002)
    Reconstituted Complex
    hit Liu SK (1998)
    bait Wong A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHC1
  • FLJ26504
  • SHC
  • SHCA
  • EG6464
    		•  The BioGRID Database Seperator SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1
    Gene Ontology: [View List]
    Invivo
    hit Nicholson PR (2001)
    hit Lazar DF (1994)
    hit VanderKuur J (1995)
    Invitro
    hit Nicholson PR (2001)
    hit Lazar DF (1994)
    hit VanderKuur J (1995)
    Affinity Capture-MS
    hit Blagoev B (2003)
    Affinity Capture-Western
    bait/hit Skolnik EY (1993)
    hit Puil L (1994)
    bait Satoh T (1996)
    bait/hit Fixman ED (1996)
    Reconstituted Complex
    hit Fixman ED (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH3KBP1
  • CIN85
  • MIG18
  • GIG10
  • RP11-345L...
    		•  The BioGRID Database Seperator OTTHUMP00000061480|c-Cbl-interacting protein|migration-inducing gene 18 protein; SH3-domain kinase binding protein 1
    Gene Ontology: [View List]
    Invivo
    bait Salvatore P (1998)
    bait Borinstein SC (2000)
    bait Buchman VL (2002)
    Invitro
    bait Salvatore P (1998)
    bait Borinstein SC (2000)
    bait Buchman VL (2002)
    Two-hybrid
    bait Borinstein SC (2000)
    bait Buchman VL (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOS1
  • GF1
  • GGF1
  • GINGF
  • EG6654
    		•  The BioGRID Database Seperator gingival fibromatosis, hereditary, 1|son of sevenless homolog 1; son of sevenless homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Invivo
    bait Chardin P (1993)
    Affinity Capture-MS
    hit Blagoev B (2003)
    Reconstituted Complex
    hit Liu SK (1998)
    bait Wong A (2002)
    Affinity Capture-Western
    hit Oneyama C (2002)
    hit Puil L (1994)
    hit Robinson A (1996)
    hit Li N (1993)
    hit Wong A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCR
  • ALL
  • BCR1
  • CML
  • EG613
    		•  The BioGRID Database Seperator breakpoint cluster region protein; breakpoint cluster region
    Gene Ontology: [View List]
    Invivo
    bait Ma G (1997)
    Invitro
    bait Ma G (1997)
    Affinity Capture-Western
    bait Million RP (2000)
    bait Million RP (2004)
    hit Puil L (1994)
    Two-hybrid
    bait Bai RY (1998)
    Far Western
    bait Million RP (2004)
    Reconstituted Complex
    hit Puil L (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Invivo
    bait Minoo P (2003)
    bait Wong L (1996)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    hit Ganju RK (2000)
    hit Bennett AM (1994)
    Far Western
    hit Ward AC (1998)
    Reconstituted Complex
    hit Yin T (1997)
    hit Tang J (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Invivo
    bait Lowenstein EJ (1992)
    Invitro
    bait Lowenstein EJ (1992)
    Affinity Capture-MS
    bait Schulze WX (2005)
    hit Blagoev B (2003)
    Affinity Capture-Western
    hit Oneyama C (2002)
    hit Wong L (1999)
    bait/hit Okutani T (1994)
    Reconstituted Complex
    bait Okutani T (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPRA
  • HEPTP
  • HLPR
  • HPTPA
  • RP4-534B8.1
    		•  The BioGRID Database Seperator Leukocyte common antigen-related peptide (protein tyrosine phosphate)|PTPLCA-related phosphatase|PTPase-alpha|protein tyrosine phosphatase, receptor type, alpha polypeptide|tyrosine phosphatase alpha; protein tyrosine phosphatase, receptor type, A
    Gene Ontology: [View List]
    Invivo
    bait den Hertog J (1994)
    bait Zheng XM (2002)
    Invitro
    bait den Hertog J (1994)
    bait Zheng XM (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait den Hertog J (1996)
    Reconstituted Complex
    hit den Hertog J (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FLT4
  • FLT41
  • PCL
  • VEGFR3
  • EG2324
    		•  The BioGRID Database Seperator vascular endothelial growth factor receptor 3; fms-related tyrosine kinase 4
    Gene Ontology: [View List]
    Invivo
    bait Fournier E (1995)
    bait Fournier E (1996)
    bait Fournier E (1999)
    Invitro
    bait Fournier E (1995)
    bait Fournier E (1996)
    bait Fournier E (1999)
    Reconstituted Complex
    bait Pajusola K (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R1
  • GRB1
  • p85-ALPHA
  • EG5295
    		•  The BioGRID Database Seperator phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit, polypeptide 1|phosphoinositide-3-kinase, regulatory subunit, polypeptide...
    Gene Ontology: [View List]
    Invivo
    bait Kharbanda S (1995)
    Invitro
    bait Kharbanda S (1995)
    Affinity Capture-Western
    hit Saleem A (1995)
    hit Wang J (1995)
    Reconstituted Complex
    hit Saleem A (1995)
    hit Wang J (1995)
    Two-hybrid
    bait Wang J (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KHDRBS1
  • Sam68
  • p62
  • FLJ34027
  • EG10657
    		•  The BioGRID Database Seperator KH domain containing, RNA binding, signal transduction associated 1; GAP-associated tyrosine phosphoprotein p62 (Sam68)
    Gene Ontology: [View List]
    Invivo
    bait Richard S (1995)
    Invitro
    bait Richard S (1995)
    Reconstituted Complex
    hit Liu SK (1998)
    bait Shen Z (1999)
    Affinity Capture-Western
    hit Oneyama C (2002)
    bait Shen Z (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LAT
  • LAT1
  • pp36
  • EG27040
    		•  The BioGRID Database Seperator 36 kDa phospho-tyrosine adaptor protein; linker for activation of T cells
    Gene Ontology: [View List]
    Invivo
    bait Hendricks-Taylor LR (1997)
    bait Zhu M (2002)
    bait Zhang W (1998)
    Invitro
    bait Hendricks-Taylor LR (1997)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Paz PE (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCKIPSD
  • AF3P21
  • DIP
  • DIP1
  • EG51517
    		•  The BioGRID Database Seperator SH3 protein interacting with Nck, 90 kDa|dia interacting protein|diaphanous protein interacting protein; NCK interacting protein with SH3 domain
    Gene Ontology: [View List]
    Invivo
    bait Fukuoka M (2001)
    Invitro
    bait Fukuoka M (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Reconstituted Complex
    hit Satoh S (2001)
    Affinity Capture-Western
    hit Satoh S (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K1
  • HPK1
  • EG11184
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase kinase kinase 1; hematopoietic progenitor kinase 1
    Gene Ontology: [View List]
    Invivo
    hit Ling P (1999)
    hit Anafi M (1997)
    Invitro
    hit Ling P (1999)
    hit Anafi M (1997)
    Reconstituted Complex
    hit Oehrl W (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV1
  • VAV
  • EG7409
    		•  The BioGRID Database Seperator oncogene vav|vav 1 oncogene|vav proto-oncogene; vav 1 guanine nucleotide exchange factor
    Gene Ontology: [View List]
    Invivo
    bait Ye ZS (1994)
    Invitro
    bait Ye ZS (1994)
    Two-hybrid
    bait Ye ZS (1994)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Song JS (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MET
  • HGFR
  • RCCP2
  • AUTS9
  • EG4233
    		•  The BioGRID Database Seperator met proto-oncogene (hepatocyte growth factor receptor); Oncogene MET|met proto-oncogene
    Gene Ontology: [View List]
    Invivo
    bait Liang Q (1998)
    bait Songyang Z (1994)
    Invitro
    bait Liang Q (1998)
    bait Songyang Z (1994)
    Reconstituted Complex
    bait Ponzetto C (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FRS2
  • FRS2A
  • FRS2alpha
  • SNT
  • EG10818
    		•  The BioGRID Database Seperator FGFR signalling adaptor|suc1-associated neurotrophic factor target; fibroblast growth factor receptor substrate 2
    Gene Ontology: [View List]
    Invivo
    bait Kouhara H (1997)
    Invitro
    bait Kouhara H (1997)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Ong SH (1996)
    bait Wong A (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WAS
  • IMD2
  • THC
  • WASP
  • EG7454
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome protein|thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
    Gene Ontology: [View List]
    Invivo
    hit O'Sullivan E ()
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Reconstituted Complex
    hit Banin S (1996)
    hit She HY (1997)
    Affinity Capture-Western
    bait/hit She HY (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BLNK
  • BLNK-s
  • Ly57
  • SLP-65
  • EG29760
    		•  The BioGRID Database Seperator B cell linker protein|B-cell linker protein; B-cell linker
    Gene Ontology: [View List]
    Invivo
    bait Wienands J (1998)
    Invitro
    bait Wienands J (1998)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Fu C (1998)
    Reconstituted Complex
    bait Engels N (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSF1R
  • C-FMS
  • CD115
  • CSFR
  • EG1436
    		•  The BioGRID Database Seperator CD115 antigen|FMS proto-oncogene|colony stimulating factor 1 receptor|macrophage colony stimulating factor I receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog
    Gene Ontology: [View List]
    Invivo
    bait Husson H (1997)
    Invitro
    bait Husson H (1997)
    Two-hybrid
    bait Mancini A (1997)
    bait Husson H (1997)
    Reconstituted Complex
    bait Mancini A (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAB1
  • EG2549
    		•  The BioGRID Database Seperator GRB2-associated binding protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Oneyama C (2002)
    hit Lewitzky M (2001)
    Reconstituted Complex
    hit Lewitzky M (2001)
    Two-hybrid
    bait Lewitzky M (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDKN1B
  • CDKN4
  • KIP1
  • P27KIP1
  • EG1027
    		•  The BioGRID Database Seperator cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor 1B
    Gene Ontology: [View List]
    Invivo
    bait Sugiyama Y (2001)
    Invitro
    bait Sugiyama Y (2001)
    Two-hybrid
    bait Sugiyama Y (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS1
  • HIRS-1
  • EG3667
    		•  The BioGRID Database Seperator insulin receptor substrate 1
    Gene Ontology: [View List]
    Invivo
    hit Wang L (1995)
    Affinity Capture-Western
    bait/hit Skolnik EY (1993)
    bait Morrison KB (2002)
    Reconstituted Complex
    hit Skolnik EY (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2
  • FADK
  • FAK
  • FAK1
  • EG5747
    		•  The BioGRID Database Seperator PTK2 protein tyrosine kinase 2; focal adhesion kinase 1
    Gene Ontology: [View List]
    Invivo
    bait Schlaepfer DD ()
    Invitro
    bait Schlaepfer DD ()
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    hit Sieg DJ (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DNM1
  • DNM
  • EG1759
    		•  The BioGRID Database Seperator dynamin 1
    Gene Ontology: [View List]
    Invivo
    bait Miki H (1994)
    bait Chen-Hwang MC (2002)
    Invitro
    bait Miki H (1994)
    bait Chen-Hwang MC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CRK
  • CRKII
  • EG1398
    		•  The BioGRID Database Seperator avian sarcoma virus CT10 (v-crk) oncogene homolog|v-crk avian sarcoma virus CT10 oncogene homolog|v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
    Gene Ontology: [View List]
    Invivo
    bait Matsuda M (1996)
    bait Riordan SM (2000)
    Invitro
    bait Matsuda M (1996)
    bait Riordan SM (2000)
    The BioGRID Database Seperator