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BioGRID | Network Layout for FYN for Homo sapiens
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FYN

 Homo sapiens
The BioGRID Database Seperator
Aliases: MGC45350, SLK, SYN, RP1-66H14.1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: OKT3-induced calcium influx regulator|c-syn protooncogene|protein-tyrosine kinase fyn|proto-oncogene tyrosine-protein kinase fyn|src-like kinase|src/yes-related novel|tyrosine kinase p59fyn(T); FYN oncogene related to SRC, FGR, YES
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 14 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with FYN

FYN was identified with 205 protein interactions and 1 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 WAS
  • IMD2
  • THC
  • WASP
  • EG7454
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome protein|thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
    Gene Ontology: [View List]
    Invivo
    hit O'Sullivan E ()
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait/hit Banin S (1996)
    Reconstituted Complex
    hit Banin S (1996)
    bait Banin S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRIN2A
  • NMDAR2A
  • NR2A
  • EG2903
    		•  The BioGRID Database Seperator N-methyl-D-aspartate receptor subunit 2A|NMDA receptor subtype 2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A
    Gene Ontology: [View List]
    Invivo
    bait Takagi N (1999)
    Invitro
    bait Takagi N (1999)
    Affinity Capture-Western
    hit Ma J (2003)
    hit Tezuka T (1999)
    bait/hit Hou XY (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2B
  • CADTK
  • CAKB
  • FADK2
  • EG2185
    		•  The BioGRID Database Seperator CAK beta|calcium-dependent tyrosine kinase|cell adhesion kinase beta|focal adhesion kinase 2|proline-rich tyrosine kinase 2|protein kinase B|protein tyrosine kinase 2 beta|related adhesion focal tyrosine kinase; PTK2B protein tyrosine kinase 2 beta
    Gene Ontology: [View List]
    Invivo
    hit Katagiri T (2000)
    hit Qian D (1997)
    Invitro
    hit Katagiri T (2000)
    hit Qian D (1997)
    Affinity Capture-Western
    bait Ganju RK (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GNB2L1
  • Gnb2-rs1
  • H12.3
  • HLC-7
  • EG10399
    		•  The BioGRID Database Seperator lung cancer oncogene 7|proliferation-inducing gene 21|protein homologous to chicken B complex protein, guanine nucleotide binding; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
    Gene Ontology: [View List]
    Invivo
    hit Yaka R (2002)
    hit Yaka R (2003)
    Invitro
    hit Yaka R (2002)
    hit Yaka R (2003)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCQ
  • PRKCT
  • nPKC-theta
  • MGC126514
  • RP11-563J...
    		•  The BioGRID Database Seperator OTTHUMP00000043364|OTTHUMP00000043365; protein kinase C, theta
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Ron D (1999)
    Biochemical Activity
    bait/hit Ron D (1999)
    Affinity Capture-Western
    bait/hit Ron D (1999)
    Two-hybrid
    bait Ron D (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NPHS1
  • CNF
  • NPHN
  • EG4868
    		•  The BioGRID Database Seperator nephrin|renal glomerulus-specific cell adhesion receptor; nephrosis 1, congenital, Finnish type (nephrin)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Lahdenpera J (2003)
    bait/hit Verma R (2003)
    Reconstituted Complex
    hit Verma R (2003)
    Biochemical Activity
    hit Verma R (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     K-ALPHA-1
  • TUBA1B
  • EG10376
    		•  The BioGRID Database Seperator alpha tubulin|tubulin, alpha, ubiquitous; tubulin, alpha 1b
    Gene Ontology: [View List]
    Invivo
    bait Klein C (2002)
    Invitro
    bait Klein C (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD2
  • SRBC
  • T11
  • RP4-655N1...
    		•  The BioGRID Database Seperator CD2 antigen (p50), sheep red blood cell receptor|OTTHUMP00000059318|lymphocyte-function antigen-2; CD2 molecule
    Gene Ontology: [View List]
    Invivo
    bait Lin H (1998)
    Invitro
    bait Lin H (1998)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPHA8
  • EEK
  • HEK3
  • KIAA1459
  • EG2046
    		•  The BioGRID Database Seperator EPH- and ELK-related tyrosine kinase|ephrin type-A receptor 8|hydroxyaryl-protein kinase|protein-tyrosine kinase|tyrosine-protein kinase receptor EEK|tyrosylprotein kinase; EPH receptor A8
    Gene Ontology: [View List]
    Invivo
    bait Choi S (1999)
    Invitro
    bait Choi S (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYK
  • EG6850
    		•  The BioGRID Database Seperator spleen tyrosine kinase
    Gene Ontology: [View List]
    Invivo
    bait Deckert M (1998)
    Invitro
    bait Deckert M (1998)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TYK2
  • JTK1
  • EG7297
    		•  The BioGRID Database Seperator tyrosine kinase 2
    Gene Ontology: [View List]
    Invivo
    hit Uddin S (1997)
    Invitro
    hit Uddin S (1997)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCAR1
  • CAS
  • CRKAS
  • P130Cas
  • EG9564
    		•  The BioGRID Database Seperator breast cancer anti-estrogen resistance 1; Crk-associated substrate p130Cas
    Gene Ontology: [View List]
    Invivo
    hit Manie SN (1997)
    Invitro
    hit Manie SN (1997)
    Two-hybrid
    bait Donaldson JC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    hit Cleghon V (1994)
    Invitro
    hit Cleghon V (1994)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH2D1A
  • DSHP
  • EBVS
  • IMD5
  • RP5-1052M...
    		•  The BioGRID Database Seperator SH2 domain protein 1A|SLAM (signaling lymphocyte activation molecule) associated protein; SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)
    Gene Ontology: [View List]
    Invitro
    bait Chan B (2003)
    Reconstituted Complex
    bait Li C (2003)
    Affinity Capture-Western
    bait Li C (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBL
  • C-CBL
  • CBL2
  • RNF55
  • EG867
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence; oncogene CBL2
    Gene Ontology: [View List]
    Invivo
    hit Deckert M (1998)
    Invitro
    hit Deckert M (1998)
    Two-hybrid
    hit Deckert M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TUBA2
  • bA408E5.3
  • TUBA3C
  • EG7278
    		•  The BioGRID Database Seperator tubulin, alpha 3c; tubulin, alpha 2
    Gene Ontology: [View List]
    Invivo
    bait Klein C (2002)
    Invitro
    bait Klein C (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UNC119
  • HRG4
  • EG9094
    		•  The BioGRID Database Seperator retinal protein 4|unc119 (C.elegans) homolog; unc-119 homolog (C. elegans)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    hit Gorska MM (2004)
    Reconstituted Complex
    bait Gorska MM (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLAUR
  • CD87
  • UPAR
  • URKR
  • EG5329
    		•  The BioGRID Database Seperator monocyte activation antigen Mo3|u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor
    Gene Ontology: [View List]
    Invitro
    bait Dumler I (1998)
    Invivo
    bait Dumler I (1998)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KHDRBS1
  • Sam68
  • p62
  • FLJ34027
  • EG10657
    		•  The BioGRID Database Seperator KH domain containing, RNA binding, signal transduction associated 1; GAP-associated tyrosine phosphoprotein p62 (Sam68)
    Gene Ontology: [View List]
    Invivo
    hit Fusaki N (1997)
    Invitro
    hit Fusaki N (1997)
    Reconstituted Complex
    hit Oneyama C (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRPC6
  • TRP6
  • FSGS2
  • FLJ11098
  • EG7225
    		•  The BioGRID Database Seperator transient receptor potential cation channel, subfamily C, member 6; transient receptor potential channel 6
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Hisatsune C (2004)
    Biochemical Activity
    hit Hisatsune C (2004)
    Reconstituted Complex
    hit Hisatsune C (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RICS
  • GC-GAP
  • GRIT
  • KIAA0712
  • EG9743
    		•  The BioGRID Database Seperator GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein; Rho GTPase-activating protein
    Gene Ontology: [View List]
    Two-hybrid
    hit Taniguchi S (2003)
    Reconstituted Complex
    bait Taniguchi S (2003)
    Affinity Capture-Western
    bait Taniguchi S (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNK2
  • ACK
  • ACK1
  • p21cdc42Hs
  • EG10188
    		•  The BioGRID Database Seperator activated Cdc42-associated kinase 1|activated p21cdc42Hs kinase; tyrosine kinase, non-receptor, 2
    Gene Ontology: [View List]
    Invivo
    hit Linseman DA (2001)
    Invitro
    hit Linseman DA (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV1
  • VAV
  • EG7409
    		•  The BioGRID Database Seperator oncogene vav|vav 1 oncogene|vav proto-oncogene; vav 1 guanine nucleotide exchange factor
    Gene Ontology: [View List]
    Invivo
    hit Michel F (1998)
    Invitro
    hit Michel F (1998)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CD44
  • CDW44
  • ECMR-III
  • IN
  • EG960
    		•  The BioGRID Database Seperator CD44 antigen|CD44 antigen (Indian blood group)|CD44 antigen (homing function and Indian blood group system)|CD44 epithelial domain (CD44E)|CDW44 antigen|GP90 lymphocyte homing/adhesion receptor|Hermes antigen|antigen gp90 homing receptor|cell adhesion molecule (CD44)|cell surface glycoprotein...
    Gene Ontology: [View List]
    Invitro
    bait Ilangumaran S (1998)
    Invivo
    bait Ilangumaran S (1998)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPHB3
  • ETK2
  • HEK2
  • TYRO6
  • EG2049
    		•  The BioGRID Database Seperator EPH-like tyrosine kinase-2|ephrin receptor EphB3|human embryo kinase 2; EPH receptor B3
    Gene Ontology: [View List]
    Invivo
    hit Hock B (1998)
    Invitro
    hit Hock B (1998)
    Two-hybrid
    hit Hock B (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZAP70
  • SRK
  • STD
  • TZK
  • EG7535
    		•  The BioGRID Database Seperator syk-related tyrosine kinase|zeta-chain (TCR) associated protein kinase (70 kD)|zeta-chain associated protein kinase 70kDa|zeta-chain associated protein kinase, 70kD; zeta-chain (TCR) associated protein kinase 70kDa
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Neumeister EN (1995)
    Phenotypic Enhancement
    bait Neumeister EN (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG2
  • EG5336
    		•  The BioGRID Database Seperator phospholipase C gamma 2|phospholipase C, gamma 2|phospholipase C, gamma 2 (phosphatidylyinositol-specific); phospholipase C, gamma 2 (phosphatidylinositol-specific)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Reconstituted Complex
    hit Pleiman CM (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PECAM1
  • CD31
  • PECAM-1
  • EG5175
    		•  The BioGRID Database Seperator platelet/endothelial cell adhesion molecule (CD31 antigen); CD31/EndoCAM|PECAM-1, CD31/EndoCAM|adhesion molecule
    Gene Ontology: [View List]
    Invitro
    hit Cicmil M (2000)
    Invivo
    hit Cicmil M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL7R
  • CD127
  • CDW127
  • IL-7R-alpha
  • EG3575
    		•  The BioGRID Database Seperator CD127 antigen|interleukin 7 receptor alpha chain; interleukin 7 receptor
    Gene Ontology: [View List]
    Invivo
    bait Seckinger P (1994)
    Invitro
    bait Seckinger P (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCAM1
  • CD56
  • MSK39
  • NCAM
  • EG4684
    		•  The BioGRID Database Seperator antigen recognized by monoclonal antibody 5.1H11|neural cell adhesion molecule, NCAM; neural cell adhesion molecule 1
    Gene Ontology: [View List]
    Invivo
    hit Beggs HE (1997)
    Invitro
    hit Beggs HE (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EVL
  • RNB6
  • EG51466
    		•  The BioGRID Database Seperator Enah/Vasp-like
    Gene Ontology: [View List]
    Invitro
    bait Lambrechts A (2000)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAF
  • CD55
  • CR
  • TC
  • RP11-357P...
    		•  The BioGRID Database Seperator CD55 antigen, decay accelerating factor for complement (Cromer blood group)|Cromer blood group|decay accelerating factor for complement|decay accelerating factor for complement (CD55, Cromer blood group system)|decay accelerating factor for complement (CD55, Cromer blood group)|decay-accelerating...
    Gene Ontology: [View List]
    Invivo
    bait Shenoy-Scaria AM (1992)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ITK
  • EMT
  • LYK
  • PSCTK2
  • EG3702
    		•  The BioGRID Database Seperator homolog of mouse T-cell itk/tsk|tyrosine-protein kinase ITK/TSK|tyrosine-protein kinase LYK; IL2-inducible T-cell kinase
    Gene Ontology: [View List]
    Invivo
    bait Bunnell SC (1996)
    Invitro
    bait Bunnell SC (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FYN
  • MGC45350
  • SLK
  • SYN
  • RP1-66H14.1
    		•  The BioGRID Database Seperator OKT3-induced calcium influx regulator|c-syn protooncogene|protein-tyrosine kinase fyn|proto-oncogene tyrosine-protein kinase fyn|src-like kinase|src/yes-related novel|tyrosine kinase p59fyn(T); FYN oncogene related to SRC, FGR, YES
    Gene Ontology: [View List]
    Invitro
    hit Noble ME (1993)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCAP1
  • SKAP55
  • SKAP1
  • EG8631
    		•  The BioGRID Database Seperator src family associated phosphoprotein 1|src kinase-associated phosphoprotein of 55 kDa; src kinase associated phosphoprotein 1
    Gene Ontology: [View List]
    Invivo
    bait Marie-Cardine A (1997)
    Invitro
    bait Marie-Cardine A (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator