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BioGRID | Network Layout for MTOR for Homo sapiens
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MTOR

 Homo sapiens
The BioGRID Database Seperator
Aliases: RAFT1, FLJ44809, FRAP1, RAPT1, FRAP2, FRAP
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: mechanistic target of rapamycin (serine/threonine kinase)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [OMIM] | [HPRD] | [Entrez Gene]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 19 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MTOR

MTOR was identified with 110 protein interactions and 1 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 RPTOR
  • Mip1
  • KOG1
  • KIAA1303
    		•  The BioGRID Database Seperator p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Jacinto E (2004) [6]
    bait/hit Sarbassov DD (2004) [8]
    bait Schalm SS (2003) [4]
    bait/hit Hara K (2002) [10]
    bait/hit Ha SH (2006) [6]
    bait/hit Wang L (2006) [6]
    bait/hit Frias MA (2006) [5]
    bait/hit Buerger C (2006) [6]
    hit McMahon LP (2005) [1]
    hit Oshiro N (2004) [2]
    hit Kawai S (2003) [3]
    hit Choi KM (2003) [1]
    hit Kim DH (2002) [4]
    hit Schieke SM (2006) [1]
    hit Sarbassov DD (2006) [2]
    hit Sarbassov DD (2005) [4]
    hit Yang Q (2006) [5]
    Affinity Capture-MS
    hit Sarbassov DD (2004) [8]
    bait Frias MA (2006) [5]
    bait Jacinto E (2006) [11]
    hit Hara K (2002) [10]
    hit Kim DH (2002) [4]
    Reconstituted Complex
    hit Nojima H (2003) [4]
    Biochemical Activity
    hit Tzatsos A (2006) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KB1
  • p70-alpha
  • STK14A
  • S6K1
    		•  The BioGRID Database Seperator ribosomal protein S6 kinase, 70kDa, polypeptide 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chiang GG (2005) [1]
    bait Holz MK (2005) [2]
    bait Hara K (2002) [10]
    hit Kim DH (2002) [4]
    hit Edinger AL (2003) [2]
    hit Takahashi T (2000) [2]
    Reconstituted Complex
    bait Holz MK (2005) [2]
    hit Isotani S (1999) [2]
    hit Long X (2005) [19]
    hit Toral-Barza L (2005) [2]
    hit Ali SM (2005) [3]
    hit Saitoh M (2002) [1]
    hit Burnett PE (1998) [2]
    hit Nojima H (2003) [4]
    Biochemical Activity
    hit Leone M (2006) [1]
    hit Sarbassov DD (2005) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EIF4EBP1
  • 4EBP1
  • MGC4316
  • PHAS-I
    		•  The BioGRID Database Seperator phosphorylated heat- and acid-stable protein regulated by insulin 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Schalm SS (2003) [4]
    hit Long X (2005) [19]
    hit Hara K (2002) [10]
    hit Takahashi T (2000) [2]
    hit Burnett PE (1998) [2]
    Affinity Capture-Western
    hit Kim DH (2002) [4]
    bait Hara K (2002) [10]
    bait Wang L (2006) [6]
    bait Wang X (2005) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RICTOR
  • mAVO3
  • MGC39830
  • DKFZp686B...
    		•  The BioGRID Database Seperator RPTOR independent companion of MTOR, complex 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Jacinto E (2004) [6]
    bait/hit Sarbassov DD (2004) [8]
    bait/hit Frias MA (2006) [5]
    bait/hit Yang Q (2006) [5]
    hit Sarbassov DD (2006) [2]
    hit Sarbassov DD (2005) [4]
    Affinity Capture-MS
    hit Sarbassov DD (2004) [8]
    bait Jacinto E (2006) [11]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FKBP1A
  • FKBP12C
  • PPIASE
  • FKBP1
  • RP11-314N...
    		•  The BioGRID Database Seperator FK506-binding protein, T-cell, 12-kD
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Jacinto E (2004) [6]
    bait Sarbassov DD (2004) [8]
    Co-crystal Structure
    bait Choi J (1996) [1]
    Two-hybrid
    hit Luker KE (2004) [3]
    Reconstituted Complex
    hit Banaszynski LA (2005) [1]
    bait Sabers CJ (1995) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHEB
  • MGC111559
  • RHEB2
    		•  The BioGRID Database Seperator Ras homolog enriched in brain 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Long X (2005) [19]
    bait Smith EM (2005) [1]
    bait Bernardi R (2006) [2]
    Reconstituted Complex
    bait/hit Long X (2005) [19]
    bait Long X (2005) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MLST8
  • WAT1
  • MGC111011
  • POP3
    		•  The BioGRID Database Seperator MTOR associated protein, LST8 homolog (S. cerevisiae)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Sarbassov DD (2005) [4]
    hit Oshiro N (2004) [2]
    hit Kawai S (2003) [3]
    Affinity Capture-MS
    hit Kawai S (2003) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPKAP1
  • SIN1g
  • SIN1b
  • JC310
  • RP11-269P...
    		•  The BioGRID Database Seperator mitogen-activated protein kinase associated protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yang Q (2006) [5]
    bait Jacinto E (2006) [11]
    Affinity Capture-MS
    bait Jacinto E (2006) [11]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AKT1
  • MGC99656
  • PRKBA
  • PKB
    		•  The BioGRID Database Seperator v-akt murine thymoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Sarbassov DD (2005) [2]
    bait Sekulic A (2000) [1]
    Protein-peptide
    bait Cheng SW (2004) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT3
  • APRF
  • MGC16063
  • HIES
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 3 (acute-phase response factor)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Yokogami K (2000) [1]
    Affinity Capture-Western
    hit Kusaba H (2005) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EIF3F
  • eIF3-p47
  • EIF3S5
    		•  The BioGRID Database Seperator eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Harris TE (2006) [13]
    Two-hybrid
    hit Harris TE (2006) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLIP1
  • CYLN1
  • CLIP-170
  • CLIP
    		•  The BioGRID Database Seperator restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Choi JH (2002) [4]
    Reconstituted Complex
    bait/hit Choi JH (2002) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GPHN
  • GEPH
  • GPHRYN
  • KIAA1385
    		•  The BioGRID Database Seperator gephyrin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sabatini DM (1999) [3]
    Reconstituted Complex
    hit Sabatini DM (1999) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBQLN1
  • DA41
  • XDRP1
  • DSK2
    		•  The BioGRID Database Seperator ubiquilin 1
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Wu S (2002) [3]
    Affinity Capture-Western
    bait Wu S (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Rheb
  • N/A
    		•  The BioGRID Database Seperator Ras homolog enriched in brain
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Buerger C (2006) [6]
    Reconstituted Complex
    hit Buerger C (2006) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MTOR
  • RAFT1
  • FLJ44809
  • FRAP1
    		•  The BioGRID Database Seperator mechanistic target of rapamycin (serine/threonine kinase)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Takahara T (2006) [1]
    hit Urano J (2007) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FBXW7
  • FLJ16457
  • SEL-10
  • FBW7
    		•  The BioGRID Database Seperator F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Mao JH (2008) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP2R2A
  • MGC52248
  • B55A
  • B55-ALPHA
    		•  The BioGRID Database Seperator Serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Peterson RT (1999) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAP1A
  • RAP1
  • KREV-1
  • SMGP21
    		•  The BioGRID Database Seperator RAP1A, member of RAS oncogene family
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Long X (2005) [19]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Rps6kb1
  • p70/85s6k
  • AI256796
  • 70kDa
  • RP23-467J...
    		•  The BioGRID Database Seperator ribosomal protein S6 kinase, 70kD, polypeptide 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit He G (2006) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLD2
  • N/A
    		•  The BioGRID Database Seperator choline phosphatase 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ha SH (2006) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Stat3
  • MGC93551
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Rajan P (2003) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TERT
  • TCS1
  • TP2
  • TRT
    		•  The BioGRID Database Seperator telomerase reverse transcriptase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Kawauchi K (2005) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EIF3C
  • MGC189744
  • FLJ78287
  • eIF3-p110
    		•  The BioGRID Database Seperator eukaryotic translation initiation factor 3, subunit 8 (110kD)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Holz MK (2005) [10]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKAA1
  • MGC57364
  • AMPK
  • AMPKa1
    		•  The BioGRID Database Seperator protein kinase, AMP-activated, alpha 1 catalytic subunit
    Gene Ontology: [View List]
    Protein-peptide
    bait Cheng SW (2004) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LRPAP1
  • MGC138272
  • MRAP
  • A2RAP
  • RP11-529E...
    		•  The BioGRID Database Seperator low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Wang L (2006) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS1
  • HIRS-1
    		•  The BioGRID Database Seperator insulin receptor substrate 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ozes ON (2001) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABL1
  • ABL
  • JTK7
  • c-ABL
  • RP11-83J2...
    		•  The BioGRID Database Seperator v-abl Abelson murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kumar V (2000) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFP
  • PFC
  • BFD
  • PFD
    		•  The BioGRID Database Seperator properdin P factor, complement
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Minami T (2001) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCD
  • nPKC-delta
  • MGC49908
  • MAY1
    		•  The BioGRID Database Seperator protein kinase C delta VIII
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kumar V (2000) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PA2G4
  • EBP1
  • p38-2G4
  • HG4-1
    		•  The BioGRID Database Seperator proliferation-associated 2G4, 38kDa
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Toral-Barza L (2005) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT1
  • ISGF-3
  • STAT91
  • DKFZp686B...
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 1, 91kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kristof AS (2003) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GDI2P
  • N/A
    		•  The BioGRID Database Seperator GDP dissociation inhibitor 2 pseudogene
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ozes ON (2001) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EIF3B
  • PRT1
  • MGC104664
  • MGC131875
    		•  The BioGRID Database Seperator eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Holz MK (2005) [10]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDK1
  • N/A
    		•  The BioGRID Database Seperator mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Isotani S (1999) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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