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BioGRID | Network Layout for EGFR for Homo sapiens
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EGFR

 Homo sapiens
The BioGRID Database Seperator
Aliases: ERBB, ERBB1, mENA, HER1, PIG61, EG1956
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 34 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with EGFR

EGFR was identified with 149 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Schulze WX (2005)
    bait Blagoev B (2003)
    Affinity Capture-Western
    bait Oneyama C (2002)
    bait Wong L (1999)
    bait/hit Okutani T (1994)
    hit Tortora G (1997)
    bait Lowenstein EJ (1992)
    bait Braverman LE (1999)
    Reconstituted Complex
    hit Okutani T (1994)
    hit Daly RJ (1996)
    hit Buday L (1994)
    bait Lowenstein EJ (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AR
  • AIS
  • DHTR
  • HUMARA
  • RP11-383C...
    		•  The BioGRID Database Seperator androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease); OTTHUMP00000061928|androgen receptor|dihydrotestosterone receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Bonaccorsi L (2004)
    hit Bonaccorsi L (2004)
    Co-localization
    bait Bonaccorsi L (2004)
    bait Bonaccorsi L (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN1
  • PTP1B
  • EG5770
    		•  The BioGRID Database Seperator non-receptor tyrosine phosphatase 1|protein tyrosine phosphatase 1B|protein tyrosine phosphatase, placental; protein tyrosine phosphatase, non-receptor type 1
    Gene Ontology: [View List]
    Invivo
    hit Jia Z (1995)
    Invitro
    hit Jia Z (1995)
    Co-crystal Structure
    bait Sarmiento M (2000)
    Biochemical Activity
    bait Zhang ZY (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DCN
  • DSPG2
  • PG40
  • PGII
  • EG1634
    		•  The BioGRID Database Seperator bone proteoglycan II|decorin proteoglycan|dermatan sulphate proteoglycans II|proteoglycan core protein|small leucine-rich protein 1B; decorin
    Gene Ontology: [View List]
    Two-hybrid
    bait Santra M (2002)
    Reconstituted Complex
    bait Santra M (2002)
    bait Iozzo RV (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBLC
  • CBL-3
  • CBL-SL
  • RNF57
  • EG23624
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence c; Cas-Br-M (murine) ectropic retroviral transforming sequence c
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kim M (1999)
    bait Keane MM (1999)
    Reconstituted Complex
    bait Keane MM (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTNNB1
  • CTNNB
  • FLJ25606
  • DKFZp686D...
  • EG1499
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), beta 1 (88kD)|catenin (cadherin-associated protein), beta 1 (88kDa; catenin (cadherin-associated protein), beta 1, 88kDa
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Hazan RB (1998)
    Affinity Capture-Western
    hit Schroeder JA (2002)
    hit Takahashi K (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Olayioye MA (1999)
    hit Keely SJ (2000)
    hit Sato K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC25A
  • CDC25A2
  • EG993
    		•  The BioGRID Database Seperator M-phase inducer phosphatase 1|cell division cycle 25A|dual specificity phosphatase CDC25A; cell division cycle 25 homolog A (S. pombe)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Wang Z (2002)
    Reconstituted Complex
    bait Wang Z (2002)
    Biochemical Activity
    bait Wang Z (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MUC1
  • CD227
  • EMA
  • H23AG
  • EG4582
    		•  The BioGRID Database Seperator DF3 antigen|H23 antigen|MUC-1/SEC|MUC-1/X|MUC1 isoform T10|MUC1 isoform T11|MUC1 isoform T12|MUC1 isoform T13|MUC1/ZD|breast carcinoma-associated antigen DF3|episialin|mucin 1|mucin 1, transmembrane|peanut-reactive urinary mucin|polymorphic epithelial mucin|tumor associated epithelial mucin;...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Schroeder JA (2001)
    bait Li Y (2001)
    Biochemical Activity
    hit Li Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOS1
  • GF1
  • GGF1
  • GINGF
  • EG6654
    		•  The BioGRID Database Seperator gingival fibromatosis, hereditary, 1|son of sevenless homolog 1; son of sevenless homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Qian X (2000)
    bait Qian X (1998)
    Reconstituted Complex
    hit Buday L (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CRK
  • CRKII
  • EG1398
    		•  The BioGRID Database Seperator avian sarcoma virus CT10 (v-crk) oncogene homolog|v-crk avian sarcoma virus CT10 oncogene homolog|v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Schulze WX (2005)
    Biochemical Activity
    hit Hashimoto Y (1998)
    Affinity Capture-Western
    bait Hashimoto Y (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNX1
  • HsT17379
  • MGC8664
  • SNX1A
  • EG6642
    		•  The BioGRID Database Seperator sorting nexin 1A; sorting nexin 1
    Gene Ontology: [View List]
    Invivo
    bait Kurten RC (1996)
    Two-hybrid
    bait Kurten RC (1996)
    Affinity Capture-Western
    bait Haft CR (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT5A
  • MGF
  • STAT5
  • EG6776
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 5A
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Schulze WX (2005)
    Affinity Capture-Western
    hit Schulze WX (2005)
    bait Olayioye MA (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN6
  • HCP
  • HCPH
  • HPTP1C
  • EG5777
    		•  The BioGRID Database Seperator 70 kda SHP-1L protein|hematopoietic cell phosphatase|hematopoietic cell protein-tyrosine phosphatase|protein-tyrosine phosphatase 1C; protein tyrosine phosphatase, non-receptor type 6
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Tomic S (1995)
    bait Keilhack H (1998)
    Reconstituted Complex
    bait Keilhack H (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCK1
  • MGC12668
  • NCK
  • NCKalpha
  • EG4690
    		•  The BioGRID Database Seperator NCK tyrosine kinase|SH2/SH3 adaptor protein NCK-alpha|melanoma NCK protein|non-catalytic region of tyrosine kinase; NCK adaptor protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Tang J (1997)
    Affinity Capture-Western
    bait Li W (1992)
    bait Braverman LE (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCK2
  • GRB4
  • NCKbeta
  • EG8440
    		•  The BioGRID Database Seperator SH2/SH3 adaptor protein NCK-beta|noncatalytic region of tyrosine kinase, beta; NCK adaptor protein 2
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Chen M (1998)
    Affinity Capture-Western
    bait Braverman LE (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAV3
  • LGMD1C
  • VIP-21
  • VIP21
  • EG859
    		•  The BioGRID Database Seperator caveolin 3; M-caveolin
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Couet J (1997)
    Reconstituted Complex
    hit Couet J (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAV1
  • CAV
  • MSTP085
  • VIP21
  • EG857
    		•  The BioGRID Database Seperator caveolae protein, 22-kD|caveolin 1|caveolin 1 caveolae protein, 22kD|caveolin 1, alpha isoform|caveolin 1, beta isoform|cell growth-inhibiting protein 32; caveolin 1, caveolae protein, 22kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Couet J (1997)
    Reconstituted Complex
    hit Couet J (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBL
  • C-CBL
  • CBL2
  • RNF55
  • EG867
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence; oncogene CBL2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ettenberg SA (1999)
    hit Tvorogov D (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT1
  • DKFZp686B...
  • ISGF-3
  • STAT91
  • EG6772
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 1|signal transducer and activator of transcription-1|transcription factor ISGF-3 components p91/p84; signal transducer and activator of transcription 1, 91kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Olayioye MA (1999)
    hit Xia L (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG1
  • PLC-II
  • PLC1
  • PLC148
  • EG5335
    		•  The BioGRID Database Seperator 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phosphol...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Tvorogov D (2002)
    bait Bedrin MS (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARF4
  • ARF2
  • EG378
    		•  The BioGRID Database Seperator ADP-ribosylation factor 4; ADP-ribosylation factor 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Kim SW (2003)
    Affinity Capture-Western
    hit Kim SW (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLSCR1
  • MMTRA1B
  • EG5359
    		•  The BioGRID Database Seperator phospholipid scramblase 1
    Gene Ontology: [View List]
    Co-fractionation
    bait Sun J (2002)
    Affinity Capture-Western
    hit Sun J (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH3KBP1
  • CIN85
  • MIG18
  • GIG10
  • RP11-345L...
    		•  The BioGRID Database Seperator OTTHUMP00000061480|c-Cbl-interacting protein|migration-inducing gene 18 protein; SH3-domain kinase binding protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Soubeyran P (2002)
    bait Szymkiewicz I (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGF
  • URG
  • EG1950
    		•  The BioGRID Database Seperator epidermal growth factor (beta-urogastrone); urogastrone
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Stortelers C (2002)
    hit Wong L (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBLB
  • DKFZp686J...
  • DKFZp779A...
  • RNF56
  • EG868
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ectropic retroviral transforming sequence b|putative protein product of Nbla00127; Cas-Br-M (murine) ecotropic retroviral transforming sequence b
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Schulze WX (2005)
    Affinity Capture-Western
    hit Ettenberg SA (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Schulze WX (2005)
    Affinity Capture-Western
    hit Tomic S (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT3
  • APRF
  • FLJ20882
  • MGC16063
  • EG6774
    		•  The BioGRID Database Seperator DNA-binding protein APRF|acute-phase response factor|signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Yuan ZL (2004)
    hit Olayioye MA (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHC1
  • FLJ26504
  • SHC
  • SHCA
  • EG6464
    		•  The BioGRID Database Seperator SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Schulze WX (2005)