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BioGRID | Network Layout for CRK for Homo sapiens
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CRK

 Homo sapiens
The BioGRID Database Seperator
Aliases: CRKII, EG1398
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: avian sarcoma virus CT10 (v-crk) oncogene homolog|v-crk avian sarcoma virus CT10 oncogene homolog|v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 9 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with CRK

CRK was identified with 82 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 BCAR1
  • CAS
  • CRKAS
  • P130Cas
  • EG9564
    		•  The BioGRID Database Seperator breast cancer anti-estrogen resistance 1; Crk-associated substrate p130Cas
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zhou B (2004)
    bait Di Stefano P (2004)
    bait/hit Hsia DA (2003)
    hit Gu J (2001)
    hit Garton AJ (1999)
    hit Qiu W (1998)
    bait Blaukat A (1999)
    Reconstituted Complex
    hit Angers-Loustau A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOCK1
  • DOCK180
  • ced5
  • RP11-82L9.1
    		•  The BioGRID Database Seperator dedicator of cyto-kinesis 1; dedicator of cytokinesis 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Hsia DA (2003)
    hit Matsuda M (1996)
    Affinity Capture-Western
    bait/hit Hsia DA (2003)
    hit Nishihara H (1999)
    hit Hasegawa H (1996)
    hit Gu J (2001)
    Co-fractionation
    hit Hasegawa H (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RICS
  • GC-GAP
  • GRIT
  • KIAA0712
  • EG9743
    		•  The BioGRID Database Seperator GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein; Rho GTPase-activating protein
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Zhao C (2003)
    Affinity Capture-Western
    bait Zhao C (2003)
    bait Moon SY (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDGFRA
  • CD140A
  • MGC74795
  • PDGFR2
  • EG5156
    		•  The BioGRID Database Seperator FIP1L1/PDGFRA fusion protein|platelet-derived growth factor receptor alpha|rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; platelet-derived growth factor receptor, alpha polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yokote K (1998)
    hit Matsumoto T (2000)
    Reconstituted Complex
    hit Matsumoto T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEDD9
  • CAS-L
  • CASL
  • HEF1
  • EG4739
    		•  The BioGRID Database Seperator Crk-associated substrate related|cas-like docking|dJ49G10.2 (Enhancer of Filamentation 1 (HEF1))|dJ761I2.1 (enhancer of filamentation (HEF1))|enhancer of filamentation 1; neural precursor cell expressed, developmentally down-regulated 9
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Minegishi M (1996)
    bait/hit Ohashi Y (1998)
    Reconstituted Complex
    hit Ohashi Y (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K1
  • HPK1
  • EG11184
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase kinase kinase 1; hematopoietic progenitor kinase 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Oehrl W (1998)
    hit Ling P (1999)
    Affinity Capture-Western
    bait Ling P (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Riordan SM (2000)
    Far Western
    hit Matsuda M (1996)
    Affinity Capture-Western
    bait/hit Okada S (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Schulze WX (2005)
    Biochemical Activity
    bait Hashimoto Y (1998)
    Affinity Capture-Western
    hit Hashimoto Y (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PXN
  • FLJ16691
  • hCG_1778014
    		•  The BioGRID Database Seperator paxillin
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Angers-Loustau A (1999)
    Affinity Capture-Western
    hit Abassi YA (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8
  • JNK
  • JNK1
  • JNK1A2
  • EG5599
    		•  The BioGRID Database Seperator JNK1 alpha protein kinase|JNK1 beta protein kinase|c-Jun N-terminal kinase 1|protein kinase JNK1|stress-activated protein kinase JNK1; mitogen-activated protein kinase 8
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Girardin SE (2001)
    Reconstituted Complex
    bait Girardin SE (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAPGEF1
  • C3G
  • DKFZp781P...
  • GRF2
  • EG2889
    		•  The BioGRID Database Seperator OTTHUMP00000064558|guanine nucleotide-releasing factor 2|guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene); Rap guanine nucleotide exchange factor (GEF) 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Tanaka S (1994)
    Far Western
    bait Tanaka S (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPS15
  • AF-1P
  • AF1P
  • MLLT5
  • EG2060
    		•  The BioGRID Database Seperator epidermal growth factor receptor pathway substrate 15; ALL1 fused gene from chromosome 1
    Gene Ontology: [View List]
    Far Western
    bait Schumacher C (1995)
    Reconstituted Complex
    bait Schumacher C (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBL
  • C-CBL
  • CBL2
  • RNF55
  • EG867
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence; oncogene CBL2
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Gesbert F (1998)
    hit Husson H (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRS4
  • IRS-4
  • PY160
  • EG8471
    		•  The BioGRID Database Seperator insulin receptor substrate 4
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Karas M (2001)
    Reconstituted Complex
    hit Koval AP (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOS1
  • GF1
  • GGF1
  • GINGF
  • EG6654
    		•  The BioGRID Database Seperator gingival fibromatosis, hereditary, 1|son of sevenless homolog 1; son of sevenless homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Okada S (1996)
    Affinity Capture-Western
    bait/hit Okada S (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDGFRB
  • CD140B
  • JTK12
  • PDGF-R-beta
  • EG5159
    		•  The BioGRID Database Seperator beta platelet-derived growth factor receptor|platelet-derived growth factor receptor beta; platelet-derived growth factor receptor, beta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Matsumoto T (2000)
    Reconstituted Complex
    hit Matsumoto T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2
  • FADK
  • FAK
  • FAK1
  • EG5747
    		•  The BioGRID Database Seperator PTK2 protein tyrosine kinase 2; focal adhesion kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Hsia DA (2003)
    Reconstituted Complex
    hit Angers-Loustau A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Xpo1
  • EG399087
    		•  The BioGRID Database Seperator CRM1/XPO1 protein
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Smith JJ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WEE1
  • DKFZp686I...
  • WEE1hu
  • FLJ16446
  • EG7465
    		•  The BioGRID Database Seperator WEE1+ homolog|wee1 tyrosine kinase|wee1+ (S. pombe) homolog|wee1-like protein kinase; WEE1 homolog (S. pombe)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Smith JJ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XPO1
  • CRM1
  • DKFZp686B...
  • EG7514
    		•  The BioGRID Database Seperator CRM1, yeast, homolog|Exportin-1 (required for chromosome region maintenance)|exportin 1|exportin 1 (CRM1, yeast, homolog); exportin 1 (CRM1 homolog, yeast)
    Gene Ontology: [View List]
    Two-hybrid
    hit Smith JJ (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SH3BP1
  • EG23616
    		•  The BioGRID Database Seperator OTTHUMP00000028981|SH3 domain binding protein 1; SH3-domain binding protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Cicchetti P (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPHB2
  • DRT
  • EPHT3
  • ERK
  • EG2048
    		•  The BioGRID Database Seperator developmentally-regulated eph-related tyrosine kinase|elk-related tyrosine kinase|eph tyrosine kinase 3|ephrin receptor EphB2|prostate cancer-brain cancer susceptibility; EPH receptor B2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Zisch AH (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHB
  • RP11-3J10.8
  • bA3J10.2
  • RP11-3J10.3
    		•  The BioGRID Database Seperator SHB (Src homology 2 domain containing) adaptor protein B|SHB adaptor protein (a Src homology 2 protein); Src homology 2 domain containing adaptor protein B
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Lu L (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Hsia DA (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZAP70
  • SRK
  • STD
  • TZK
  • EG7535
    		•  The BioGRID Database Seperator syk-related tyrosine kinase|zeta-chain (TCR) associated protein kinase (70 kD)|zeta-chain associated protein kinase 70kDa|zeta-chain associated protein kinase, 70kD; zeta-chain (TCR) associated protein kinase 70kDa
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Gelkop S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CBLC
  • CBL-3
  • CBL-SL
  • RNF57
  • EG23624
    		•  The BioGRID Database Seperator Cas-Br-M (murine) ecotropic retroviral transforming sequence c; Cas-Br-M (murine) ectropic retroviral transforming sequence c
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Keane MM (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MICAL1
  • DKFZp434B...
  • FLJ11937
  • FLJ21739
  • RP5-919F1...
    		•  The BioGRID Database Seperator CasL interacting molecule|NEDD9 interacting protein with calponin homology and LIM domains; microtubule associated monoxygenase, calponin and LIM domain containing 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Suzuki T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN1
  • PTP1B
  • EG5770
    		•  The BioGRID Database Seperator non-receptor tyrosine phosphatase 1|protein tyrosine phosphatase 1B|protein tyrosine phosphatase, placental; protein tyrosine phosphatase, non-receptor type 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Liu F (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSEN
  • DREAM
  • KCHIP3
  • KCNIP3
  • EG30818
    		•  The BioGRID Database Seperator A-type potassium channel modulatory protein 3|DRE-antagonist modulator|Kv channel interacting protein 3|calsenilin, presenilin-binding protein, EF hand transcription factor|potassium channel interacting protein 3; Kv channel interacting protein 3, calsenilin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kashiwa A (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSMC6
  • CADP44
  • MGC12520
  • P44
  • EG5706
    		•  The BioGRID Database Seperator 26S protease regulatory subunit S10B|conserved ATPase domain protein 44|proteasome 26S ATPase subunit 6|proteasome subunit p42; proteasome (prosome, macropain) 26S subunit, ATPase, 6
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNIP
  • KIAA1684
  • EG80725
    		•  The BioGRID Database Seperator P130Cas-associated protein|p140Cap; SNAP25-interacting protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Di Stefano P (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K5
  • GCKR
  • KHS
  • KHS1
  • EG11183
    		•  The BioGRID Database Seperator mitogen-activated protein kinase kinase kinase kinase 5; kinase homologous to SPS1/STE20
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shi CS (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FRS2
  • FRS2A
  • FRS2alpha
  • SNT
  • EG10818
    		•  The BioGRID Database Seperator FGFR signalling adaptor|suc1-associated neurotrophic factor target; fibroblast growth factor receptor substrate 2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Meakin SO (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DPPA4
  • 2410091M2...
  • FLJ10713
  • EG55211
    		•  The BioGRID Database Seperator developmental pluripotency associated 4
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AVIL
  • ADVIL
  • DOC6
  • FLJ12386
  • EG10677
    		•  The BioGRID Database Seperator advillin
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Takami M (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DDEF1
  • ASAP1
  • KIAA1249
  • PAG2
  • EG50807
    		•  The BioGRID Database Seperator development and differentiation enhancing factor 1; centaurin, beta 4
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Brown MT (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KHDRBS1
  • Sam68
  • p62
  • FLJ34027
  • EG10657
    		•  The BioGRID Database Seperator KH domain containing, RNA binding, signal transduction associated 1; GAP-associated tyrosine phosphoprotein p62 (Sam68)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Koch CA (1992)
    The BioGRID Database Seperator
    The BioGRID Database Seperator