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CLU
Homo sapiens
Aliases:
APOJ, SGP2, MGC24903, SGP-2, AAG4, KUB1, TRPM2, SP-40, CLI, TRPM-2
Description:
clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)
Links:
[UniprotKB]
|
[OMIM]
|
[HPRD]
|
[Entrez Gene]
Gene Ontology:
8 total GO annotations for this record.
[view list]
Function
Process
Component
•
protein binding
(
IPI
)
•
reverse cholesterol trans ...
(
TAS
)
•
release of cytochrome c f ...
(
IC
)
•
lipid metabolic process
(
NAS
)
•
negative regulation of pr ...
(
IMP
)
•
mitochondrion
(
IDA
)
•
extracellular space
(
NAS
)
•
spherical high-density li ...
(
IDA
)
Download interactions associated with CLU
CLU was identified with
20
protein interactions
Name
Aliases
Description
Evidence Code
Role
Source [Interactions]
XRCC6
CTC75
ML8
CTCBF
CTA-216E1...
X-ray repair complementing defective repair in Chinese hamster cells 6
Gene Ontology:
[View List]
Two-hybrid
bait
Yang CR (1999)
[
7
]
hit
Leskov KS (2003)
[
3
]
Far Western
bait
Yang CR (1999)
[
7
]
Affinity Capture-Western
bait/hit
Yang CR (1999)
[
7
]
Reconstituted Complex
hit
Leskov KS (2003)
[
3
]
TGFBR2
TGFR-2
FAA3
MFS2
transforming growth factor, beta receptor II (70/80kDa)
Gene Ontology:
[View List]
Two-hybrid
hit
Reddy KB (1996)
[
6
]
Reconstituted Complex
bait
Reddy KB (1996)
[
6
]
Affinity Capture-Western
bait
Reddy KB (1996)
[
6
]
TGFBR1
ALK5
ALK-5
LDS1A
transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)
Gene Ontology:
[View List]
Two-hybrid
hit
Reddy KB (1996)
[
6
]
Reconstituted Complex
bait
Reddy KB (1996)
[
6
]
Affinity Capture-Western
bait
Reddy KB (1996)
[
6
]
LEP
FLJ94114
OB
OBS
leptin (murine obesity homolog)
Gene Ontology:
[View List]
Reconstituted Complex
bait
Bajari TM (2003)
[
4
]
Affinity Capture-Western
hit
Bajari TM (2003)
[
4
]
C9
N/A
complement component 9
Gene Ontology:
[View List]
Reconstituted Complex
hit
Tschopp J (1993)
[
3
]
LRP2
DBS
gp330
low density lipoprotein-related protein 2
Gene Ontology:
[View List]
Reconstituted Complex
hit
Kounnas MZ (1995)
[
2
]
C7
N/A
complement component C7
Gene Ontology:
[View List]
Reconstituted Complex
hit
Tschopp J (1993)
[
3
]
CLU
APOJ
SGP2
MGC24903
clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)
Gene Ontology:
[View List]
Two-hybrid
hit
Leskov KS (2003)
[
3
]
VLDLR
VLDLRCH
FLJ35024
CHRMQ1
RP11-320E...
very low density lipoprotein receptor
Gene Ontology:
[View List]
Far Western
bait
Bajari TM (2003)
[
4
]
MMP25
MMPL1
MT-MMP6
MMP20
membrane-type 6 matrix metalloproteinase
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Matsuda A (2003)
[
1
]
C8B
MGC163447
complement component 8, beta polypeptide
Gene Ontology:
[View List]
Reconstituted Complex
hit
Tschopp J (1993)
[
3
]
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Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.