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BioGRID | Network Layout for CASP3 for Homo sapiens
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CASP3

 Homo sapiens
The BioGRID Database Seperator
Aliases: CPP32, CPP32B, SCA-1, EG836
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: PARP cleavage protease|SREBP cleavage activity 1|Yama|apopain|caspase 3|caspase 3, apoptosis-related cysteine protease|cysteine protease CPP32|procaspase3; caspase 3, apoptosis-related cysteine peptidase
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 4 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with CASP3

CASP3 was identified with 69 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 BIRC4
  • API3
  • ILP1
  • MIHA
  • RP1-315G1.5
    		•  The BioGRID Database Seperator X-linked inhibitor of apoptosis|apoptosis inhibitor 3|baculoviral IAP repeat-containing protein 4; baculoviral IAP repeat-containing 4
    Gene Ontology: [View List]
    Invivo
    hit Deveraux QL (1997)
    Invitro
    hit Deveraux QL (1997)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Suzuki Y (2001)
    bait Silke J (2002)
    Reconstituted Complex
    bait Suzuki Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NFE2L2
  • NRF2
  • EG4780
    		•  The BioGRID Database Seperator nuclear factor (erythroid-derived 2)-like 2
    Gene Ontology: [View List]
    Invivo
    hit Ohtsubo T (1999)
    Invitro
    hit Ohtsubo T (1999)
    Two-hybrid
    hit Ohtsubo T (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HCLS1
  • HS1
  • CTTNL
  • EG3059
    		•  The BioGRID Database Seperator hematopoietic cell-specific Lyn substrate 1; cortactin-like
    Gene Ontology: [View List]
    Invitro
    bait Chen YR (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Biochemical Activity
    hit Ruzzene M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSPD1
  • CPN60
  • GROEL
  • HSP60
  • EG3329
    		•  The BioGRID Database Seperator P60 lymphocyte protein|chaperonin|heat shock 60kD protein 1 (chaperonin)|heat shock protein 60|heat shock protein 65|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1|spastic paraplegia 13 (autosomal dominant); heat shock 60kDa protein 1 (chaperonin)
    Gene Ontology: [View List]
    Invivo
    hit Xanthoudakis S (1999)
    hit Samali A (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLK
  • KIAA0204
  • STK2
  • bA16H23.1
  • EG9748
    		•  The BioGRID Database Seperator CTCL tumor antigen se20-9|OTTHUMP00000059183|SNF1 (sucrose nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose nonfermenting like kinase|SNF1 sucrose nonfermenting like kinase|Ste20-related serine/threonine kinase|serine/threonine kinase 2; STE20-like kinase (yeast)
    Gene Ontology: [View List]
    Invivo
    hit Sabourin LA (2000)
    Invitro
    hit Sabourin LA (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BIRC2
  • API1
  • HIAP2
  • Hiap-2
  • EG329
    		•  The BioGRID Database Seperator NFR2-TRAF signalling complex protein|apoptosis inhibitor 1|baculoviral IAP repeat-containing protein 2; baculoviral IAP repeat-containing 2
    Gene Ontology: [View List]
    Invitro
    hit Roy N (1997)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP3
  • CPP32
  • CPP32B
  • SCA-1
  • EG836
    		•  The BioGRID Database Seperator PARP cleavage protease|SREBP cleavage activity 1|Yama|apopain|caspase 3|caspase 3, apoptosis-related cysteine protease|cysteine protease CPP32|procaspase3; caspase 3, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Invitro
    hit Riedl SJ (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GORASP1
  • FLJ23443
  • GOLPH5
  • GRASP65
  • EG64689
    		•  The BioGRID Database Seperator Golgi peripheral membrane protein p65|Golgi phosphoprotein 5|Golgi reassembly and stacking protein 1|Golgi reassembly and stacking protein, 65 kDa|Golgi reassembly stacking protein 1; golgi reassembly stacking protein 1, 65kDa
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Biochemical Activity
    hit Lane JD (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DCC
  • CRC18
  • CRCR1
  • EG1630
    		•  The BioGRID Database Seperator deleted in colorectal cancer protein; deleted in colorectal carcinoma
    Gene Ontology: [View List]
    Two-hybrid
    bait Forcet C (2001)
    Affinity Capture-Western
    hit Forcet C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF3
  • CAP-1
  • CD40bp
  • CRAF1
  • EG7187
    		•  The BioGRID Database Seperator CD40 associated protein 1|CD40 binding protein|CD40 receptor associated factor 1|LMP1 associated protein; TNF receptor-associated factor 3
    Gene Ontology: [View List]
    Biochemical Activity
    hit Lee ZH (2001)
    hit Leo E (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BIRC5
  • API4
  • EPR-1
  • EG332
    		•  The BioGRID Database Seperator apoptosis inhibitor 4|baculoviral IAP repeat-containing protein 5|survivin variant 3 alpha; baculoviral IAP repeat-containing 5 (survivin)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Reconstituted Complex
    bait Tamm I (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFLAR
  • CASH
  • CASP8AP1
  • CLARP
  • EG8837
    		•  The BioGRID Database Seperator FADD-like anti-apoptotic molecule; Inhibitor of FLICE; Caspase-related inducer of apoptosis; Caspase homolog; Caspase-like apoptosis regulatory protein|usurpin beta; CASP8 and FADD-like apoptosis regulator
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    bait Shu HB (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VDP
  • P115
  • TAP
  • USO1
  • EG8615
    		•  The BioGRID Database Seperator USO1 homolog, vesicle docking protein|transcytosis associated protein|transcytosis-associated protein|vesicle docking protein p115; USO1 homolog, vesicle docking protein (yeast)
    Gene Ontology: [View List]
    Invivo
    hit Chiu R (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TGM2
  • TG2
  • TGC
  • EG7052
    		•  The BioGRID Database Seperator C polypeptide|TGase C|TGase-H|protein-glutamine-gamma-glutamyltransferase|tissue transglutaminase|transglutaminase 2|transglutaminase C; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
    Gene Ontology: [View List]
    Invitro
    hit Fabbi M (1999)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMX
  • ETK
  • PSCTK2
  • PSCTK3
  • EG660
    		•  The BioGRID Database Seperator BMX non-receptor tyrosine kinase
    Gene Ontology: [View List]
    Invivo
    hit Wu YM (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP3CA
  • CALN
  • CALNA
  • CALNA1
  • EG5530
    		•  The BioGRID Database Seperator protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; calcineurin A alpha
    Gene Ontology: [View List]
    Invitro
    hit Mukerjee N (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DCTN1
  • DAP-150
  • DP-150
  • P135
  • EG1639
    		•  The BioGRID Database Seperator 150 kDa dynein-associated polypeptide|dynactin 1|p150, Glued (Drosophila) homolog|p150-glued; dynactin 1 (p150, glued homolog, Drosophila)
    Gene Ontology: [View List]
    Invivo
    hit Lane JD (2001)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LMNB1
  • LMN
  • LMN2
  • LMNB
  • EG4001
    		•  The BioGRID Database Seperator lamin B1
    Gene Ontology: [View List]
    Invivo
    hit Chiarini A (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2
  • Bcl-2
  • EG596
    		•  The BioGRID Database Seperator B-cell lymphoma protein 2; B-cell CLL/lymphoma 2
    Gene Ontology: [View List]
    Invivo
    hit Tomicic MT (2002)
    Biochemical Activity
    hit Liang Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NDUFS1
  • CI-75Kd
  • MGC26839
  • PRO1304
  • EG4719
    		•  The BioGRID Database Seperator NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa|NADH dehydrogenase (ubiquinone), Fe-S protein-1 (75kD)|NADH-coenzyme Q reductase|complex I, mitochondrial respiratory chain, 75-kD subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSEN1
  • AD3
  • FAD
  • PS1
  • EG5663
    		•  The BioGRID Database Seperator presenilin 1 (Alzheimer disease 3); presenilin 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BLM
  • BS
  • RECQ2
  • RECQL2
  • EG641
    		•  The BioGRID Database Seperator Bloom syndrome protein; Bloom syndrome
    Gene Ontology: [View List]
    Biochemical Activity
    hit Freire R (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTNNB1
  • CTNNB
  • FLJ25606
  • DKFZp686D...
  • EG1499
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), beta 1 (88kD)|catenin (cadherin-associated protein), beta 1 (88kDa; catenin (cadherin-associated protein), beta 1, 88kDa
    Gene Ontology: [View List]
    Invivo
    hit Brancolini C (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BIRC7
  • KIAP
  • LIVIN
  • ML-IAP
  • EG79444
    		•  The BioGRID Database Seperator baculoviral IAP repeat-containing protein 7|kidney inhibitor of apoptosis protein|livin inhibitor of apoptosis|livin inhibitor-of-apoptosis|melanoma inhibitor of apoptosis protein; baculoviral IAP repeat-containing 7 (livin)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kasof GM (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SREBF2
  • SREBP2
  • EG6721
    		•  The BioGRID Database Seperator OTTHUMP00000028740|sterol regulatory element-binding protein 2|sterol regulatory element-binding transcription factor 2; sterol regulatory element binding transcription factor 2
    Gene Ontology: [View List]
    Biochemical Activity
    bait Wang X (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PARG
  • PARG99
  • EG8505
    		•  The BioGRID Database Seperator poly(ADP-ribose) glycohydrolase 60 kDa isoform; poly (ADP-ribose) glycohydrolase
    Gene Ontology: [View List]
    Biochemical Activity
    hit Affar EB (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BID
  • MGC15319
  • MGC42355
  • FP497
  • EG637
    		•  The BioGRID Database Seperator BH3-interacting domain death agonist|Human BID coding sequence|apoptic death agonist|desmocollin type 4; BH3 interacting domain death agonist
    Gene Ontology: [View List]
    Biochemical Activity
    hit Paroni G (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATXN3
  • ATX3
  • MJD
  • MJD1
  • EG4287
    		•  The BioGRID Database Seperator Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3)|josephin; ataxin 3
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP2
  • CASP-2
  • ICH-1L
  • ICH-1L/1S
  • EG835
    		•  The BioGRID Database Seperator ICH-1 protease|NEDD2 apoptosis regulatory|caspase 2|caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2); caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)
    Gene Ontology: [View List]
    Biochemical Activity
    hit Paroni G (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MCL1
  • EAT
  • MCL1L
  • MCL1S
  • EG4170
    		•  The BioGRID Database Seperator induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia sequence 1|myeloid cell leukemia sequence 1, isoform 1; myeloid cell leukemia sequence 1 (BCL2-related)
    Gene Ontology: [View List]
    Biochemical Activity
    hit Weng C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRT8
  • CARD2
  • CK8
  • CYK8
  • EG3856
    		•  The BioGRID Database Seperator cytokeratin 8|keratin, type II cytoskeletal 8; keratin 8
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PICALM
  • CALM
  • CLTH
  • LAP
  • EG8301
    		•  The BioGRID Database Seperator CALM/AF10 fusion protein|clathrin assembly lymphoid-myeloid leukemia|phosphatidylinositol-binding clathrin assembly protein; phosphatidylinositol binding clathrin assembly protein
    Gene Ontology: [View List]
    Invitro
    hit Kim JA (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSPE1
  • CPN10
  • GROES
  • HSP10
  • EG3336
    		•  The BioGRID Database Seperator chaperonin 10|heat shock 10kD protein 1 (chaperonin 10)|heat shock 10kDa protein 1; heat shock 10kDa protein 1 (chaperonin 10)
    Gene Ontology: [View List]
    Invitro
    hit Samali A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BIRC3
  • AIP1
  • API2
  • CIAP2
  • EG330
    		•  The BioGRID Database Seperator TNFR2-TRAF signaling complex protein|apoptosis inhibitor 2|baculoviral IAP repeat-containing protein 3|inhibitor of apoptosis protein 1|mammalian IAP homolog C; baculoviral IAP repeat-containing 3
    Gene Ontology: [View List]
    Invitro
    bait Roy N (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDE5A
  • CGB-PDE
  • CN5A
  • PDE5
  • EG8654
    		•  The BioGRID Database Seperator cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase|phosphodiesterase 5A; phosphodiesterase 5A, cGMP-specific
    Gene Ontology: [View List]
    Invitro
    hit Frame M (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRP72
  • EG6731
    		•  The BioGRID Database Seperator signal recognition particle 72kDa
    Gene Ontology: [View List]
    Invitro
    hit Utz PJ (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RFC1
  • A1
  • MGC51786
  • MHCBFB
  • EG5981
    		•  The BioGRID Database Seperator MHC binding factor, beta|replication factor C (activator 1) 1 (145kD)|replication factor C large subunit|replication factor C1; replication factor C (activator 1) 1, 145kDa
    Gene Ontology: [View List]
    Invitro
    hit Ubeda M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSEN
  • DREAM
  • KCHIP3
  • KCNIP3
  • EG30818
    		•  The BioGRID Database Seperator A-type potassium channel modulatory protein 3|DRE-antagonist modulator|Kv channel interacting protein 3|calsenilin, presenilin-binding protein, EF hand transcription factor|potassium channel interacting protein 3; Kv channel interacting protein 3, calsenilin
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRT18
  • CYK18
  • K18
  • EG3875
    		•  The BioGRID Database Seperator cell proliferation-inducing protein 46|cytokeratin 18; keratin 18
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DFFA
  • DFF-45
  • DFF1
  • ICAD
  • EG1676
    		•  The BioGRID Database Seperator DFF45|DNA fragmentation factor, 45 kD, alpha polypeptide|DNA fragmentation factor, 45 kD, alpha subunit; DNA fragmentation factor, 45kDa, alpha polypeptide
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAE
  • 14-3-3E
  • KCIP-1
  • MDCR
  • EG7531
    		•  The BioGRID Database Seperator 14-3-3 epsilon|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DEDD
  • CASP8IP1
  • DEDD1
  • DEFT
  • EG9191
    		•  The BioGRID Database Seperator death effector domain-containing|death effector domain-containi