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BioGRID | Network Layout for BCL2 for Homo sapiens
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BCL2

 Homo sapiens
The BioGRID Database Seperator
Aliases: Bcl-2, EG596
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: B-cell lymphoma protein 2; B-cell CLL/lymphoma 2
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 29 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with BCL2

BCL2 was identified with 110 protein interactions
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 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 HRK
  • DP5
  • HARAKIRI
  • EG8739
    		•  The BioGRID Database Seperator BCL2-interacting protein|activator of apoptosis Hrk|death protein 5|harakiri; harakiri, BCL2 interacting protein (contains only BH3 domain)
    Gene Ontology: [View List]
    Invivo
    hit Imaizumi K (1999)
    Two-hybrid
    hit Imaizumi K (1999)
    bait Inohara N (1997)
    Protein-peptide
    hit Chen L (2005)
    Affinity Capture-Western
    bait Inohara N (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Invivo
    bait Reed JC (1996)
    Invitro
    bait Reed JC (1996)
    Reconstituted Complex
    bait Wang HG (1996)
    Two-hybrid
    hit Wang HG (1996)
    Affinity Capture-Western
    hit Wang HG (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAX
  • Bax zeta
  • EG581
    		•  The BioGRID Database Seperator BCL2-associated X protein; apoptosis regulator BAX
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Hoetelmans RW (2004)
    hit Lin B (2004)
    bait Oltvai ZN (1993)
    Reconstituted Complex
    hit Lin B (2004)
    Two-hybrid
    bait Komatsu K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAD
  • BBC2
  • BCL2L8
  • EG572
    		•  The BioGRID Database Seperator BCL-X/BCL-2 binding protein|BCL2-antagonist of cell death protein|BCL2-binding component 6|BCL2-binding protein; BCL2-antagonist of cell death
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chen L (2005)
    bait Yang E (1995)
    Two-hybrid
    bait Yang E (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BNIPL
  • BNIP-S
  • BNIPL-1
  • BNIPL-2
  • EG149428
    		•  The BioGRID Database Seperator BCL2/adenovirus E1B 19kD interacting protein like; BNIP-2 similar
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Qin W (2003)
    Affinity Capture-Western
    bait/hit Qin W (2003)
    Reconstituted Complex
    hit Yasuda M (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FKBP8
  • FKBP38
  • FKBPr38
  • EG23770
    		•  The BioGRID Database Seperator FK506 binding protein 8 (38kD)|FK506-binding protein 8|FK506-binding protein 8 (38kD); FK506 binding protein 8, 38kDa
    Gene Ontology: [View List]
    Invitro
    bait Shirane M (2003)
    Invivo
    bait Shirane M (2003)
    Two-hybrid
    bait Shirane M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BNIP2
  • BNIP-2
  • NIP2
  • EG663
    		•  The BioGRID Database Seperator BCL2/adenovirus E1B 19kD interacting protein 2|BCL2/adenovirus E1B 19kD-interacting protein 2; BCL2/adenovirus E1B 19kDa interacting protein 2
    Gene Ontology: [View List]
    Invitro
    bait Boyd JM (1994)
    Two-hybrid
    bait Qin W (2003)
    bait Boyd JM (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NR4A1
  • GFRP1
  • HMR
  • MGC9485
  • EG3164
    		•  The BioGRID Database Seperator TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|orphan nuclear receptor HMR|steroid receptor TR3; nuclear receptor subfamily 4, group A, member 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Lin B (2004)
    Two-hybrid
    hit Lin B (2004)
    Affinity Capture-Western
    bait/hit Lin B (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BNIP3
  • NIP3
  • EG664
    		•  The BioGRID Database Seperator BCL2/adenovirus E1B 19kDa interacting protein 3; BCL2/adenovirus E1B 19kD-interacting protein 3
    Gene Ontology: [View List]
    Invivo
    bait Ray R (2000)
    Invitro
    bait Ray R (2000)
    Two-hybrid
    bait Ray R (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BNIP3L
  • BNIP3a
  • NIX
  • EG665
    		•  The BioGRID Database Seperator BCL2/adenovirus E1B 19-kd protein-interacting protein 3a|BCL2/adenovirus E1B 19kD-interacting protein 3-like|adenovirus E1B19k-binding protein B5; BCL2/adenovirus E1B 19kDa interacting protein 3-like
    Gene Ontology: [View List]
    Invivo
    bait Imazu T (1999)
    Invitro
    bait Imazu T (1999)
    Two-hybrid
    bait Imazu T (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC2
  • CDK1
  • DKFZp686L...
  • MGC111195
  • EG983
    		•  The BioGRID Database Seperator cell cycle controller CDC2|cell division control protein 2 homolog|cell division cycle 2 protein|cyclin-dependent kinase 1|p34 protein kinase; cell division cycle 2, G1 to S and G2 to M
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Pathan N ()
    hit Pathan N ()
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP3CA
  • CALN
  • CALNA
  • CALNA1
  • EG5530
    		•  The BioGRID Database Seperator protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; calcineurin A alpha
    Gene Ontology: [View List]
    Invivo
    hit Shibasaki F (1997)
    hit Shibasaki F (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BID
  • MGC15319
  • MGC42355
  • FP497
  • EG637
    		•  The BioGRID Database Seperator BH3-interacting domain death agonist|Human BID coding sequence|apoptic death agonist|desmocollin type 4; BH3 interacting domain death agonist
    Gene Ontology: [View List]
    Protein-peptide
    hit Chen L (2005)
    bait Real PJ (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PMAIP1
  • APR
  • NOXA
  • EG5366
    		•  The BioGRID Database Seperator phorbol-12-myristate-13-acetate-induced protein 1; adult T cell leukemia-derived PMA-responsive
    Gene Ontology: [View List]
    Invivo
    bait Oda E (2000)
    Protein-peptide
    hit Chen L (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BIK
  • BIP1
  • BP4
  • NBK
  • EG638
    		•  The BioGRID Database Seperator BCL2-interacting killer|OTTHUMP00000028974|apoptosis-inducing NBK; BCL2-interacting killer (apoptosis-inducing)
    Gene Ontology: [View List]
    Protein-peptide
    hit Chen L (2005)
    Affinity Capture-Western
    bait Gillissen B (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYC
  • c-Myc
  • EG4609
    		•  The BioGRID Database Seperator avian myelocytomatosis viral oncogene homolog|myc proto-oncogene protein|v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Jin Z (2004)
    Co-localization
    hit Jin Z (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2L1
  • BCL-XL/S
  • BCL2L
  • BCLX
  • EG598
    		•  The BioGRID Database Seperator BCL2-like 1
    Gene Ontology: [View List]
    Protein-peptide
    bait Zhang H (2002)
    Affinity Capture-Western
    hit Lin B (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAPN2
  • CANPL2
  • CANPml
  • mCANP
  • EG824
    		•  The BioGRID Database Seperator M-calpain|calcium-activated neutral proteinase|calpain 2, large [catalytic] subunit|calpain 2, large subunit|calpain M-type|calpain, large polypeptide L2|millimolar-calpain; calpain 2, (m/II) large subunit
    Gene Ontology: [View List]
    Biochemical Activity
    bait Gil-Parrado S (2002)
    Reconstituted Complex
    bait Gil-Parrado S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRAS
  • EG6237
    		•  The BioGRID Database Seperator related RAS viral (r-ras) oncogene homolog; Oncogene RRAS
    Gene Ontology: [View List]
    Two-hybrid
    hit Fernandez-Sarabia MJ (1993)
    Affinity Capture-Western
    hit Fernandez-Sarabia MJ (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BECN1
  • ATG6
  • VPS30
  • beclin1
  • EG8678
    		•  The BioGRID Database Seperator beclin 1|beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)
    Gene Ontology: [View List]
    Two-hybrid
    hit Liang XH (1998)
    FRET
    hit Liang XH (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOD1
  • ALS
  • ALS1
  • IPOA
  • EG6647
    		•  The BioGRID Database Seperator Cu /Zn superoxide dismutase|Cu/Zn superoxide dismutase|SOD, soluble|indophenoloxidase A|superoxide dismutase (aa 120-154)|superoxide dismutase 1, soluble|superoxide dismutase, cystolic; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Pasinelli P (2004)
    Reconstituted Complex
    bait/hit Pasinelli P (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSEN1
  • AD3
  • FAD
  • PS1
  • EG5663
    		•  The BioGRID Database Seperator presenilin 1 (Alzheimer disease 3); presenilin 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Alberici A (1999)
    Affinity Capture-Western
    hit Alberici A (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCAP31
  • 6C6-AG
  • BAP31
  • CDM
  • EG10134
    		•  The BioGRID Database Seperator B-cell receptor-associated protein 31; accessory protein BAP31
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Ng FW (1997)
    Affinity Capture-Western
    bait Ng FW (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD9A
  • RAD9
  • EG5883
    		•  The BioGRID Database Seperator RAD9 homolog|cell cycle checkpoint control protein; RAD9 homolog A (S. pombe)
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Komatsu K (2000)
    Affinity Capture-Western
    bait/hit Komatsu K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BBC3
  • JFY1
  • PUMA
  • PUMA/JFY1
  • EG27113
    		•  The BioGRID Database Seperator Bcl-2 binding component 3; BCL2 binding component 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chen L (2005)
    bait/hit Nakano K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PARP1
  • ADPRT
  • ADPRT1
  • PARP
  • RP11-125A...
    		•  The BioGRID Database Seperator ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)|ADP-ribosyltransferase NAD(+)|poly(ADP-ribose) polymerase|poly(ADP-ribose) synthetase|poly(ADP-ribosyl)transferase; poly (ADP-ribose) polymerase family, member 1
    Gene Ontology: [View List]
    Invivo
    bait Song D (2002)
    Invitro
    bait Song D (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAG3
  • BAG-3
  • BIS
  • CAIR-1
  • EG9531
    		•  The BioGRID Database Seperator BAG-family molecular chaperone regulator-3|BCL2-binding athanogene 3|Bcl-2-binding protein|docking protein CAIR-1; BCL2-associated athanogene 3
    Gene Ontology: [View List]
    Invitro
    bait Liao Q (2001)
    Invivo
    bait Liao Q (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTN4
  • ASY
  • NI220/250
  • NOGO
  • EG57142
    		•  The BioGRID Database Seperator Human NogoA|My043 protein|foocen|neurite growth inhibitor 220|neurite outgrowth inhibitor|neuroendocrine-specific protein C homolog|reticulon 5; reticulon 4
    Gene Ontology: [View List]
    Two-hybrid
    bait Tagami S (2000)
    Affinity Capture-Western
    bait/hit Tagami S (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAK1
  • BAK
  • BCL2L7
  • CDN1
  • EG578
    		•  The BioGRID Database Seperator BCL2-like 7 protein|Bcl-2 homologous antagonist/killer|OTTHUMP00000039620|apoptosis regulator BAK|pro-apoptotic protein BAK; BCL2-antagonist/killer 1
    Gene Ontology: [View List]
    Invitro
    bait Enyedy IJ (2001)
    Affinity Capture-Western
    hit Lin B (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BNIP1
  • NIP1
  • TRG-8
  • SEC20
  • EG662
    		•  The BioGRID Database Seperator BCL2/adenovirus E1B 19kD interacting protein 1|BCL2/adenovirus E1B 19kD-interacting protein 1; BCL2/adenovirus E1B 19kDa interacting protein 1
    Gene Ontology: [View List]
    Invitro
    bait Zhang H (1999)
    Two-hybrid
    bait Zhang H (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2L11
  • BAM
  • BIM
  • BOD
  • EG10018
    		•  The BioGRID Database Seperator BCL2-like 11|bcl-2 interacting mediator of cell death|bcl-2 interacting protein Bim|bcl-2-related ovarian death agonist; BCL2-like 11 (apoptosis facilitator)
    Gene Ontology: [View List]
    Invivo
    bait O'Connor L (1998)
    Affinity Capture-Western
    bait Chen L (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMN1
  • BCD541
  • SMA1
  • SMA2
  • EG6606
    		•  The BioGRID Database Seperator gemin 1|spinal muscular atrophy (Werdnig-Hoffmann disease, Kugelberg-Welander disease); survival of motor neuron 1, telomeric
    Gene Ontology: [View List]
    Invitro
    bait Iwahashi H (1997)
    Two-hybrid
    bait Iwahashi H (1997)