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BioGRID | Network Layout for APP for Homo sapiens
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APP

 Homo sapiens
The BioGRID Database Seperator
Aliases: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2, EG351
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: A4 amyloid protein|amyloid beta A4 protein|amyloid-beta protein|beta-amyloid peptide|cerebral vascular amyloid peptide|protease nexin-II; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 12 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with APP

APP was identified with 59 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 APBB1
  • FE65
  • MGC:9072
  • RIR
  • EG322
    		•  The BioGRID Database Seperator adaptor protein FE65a2|amyloid beta A4 precursor protein-binding, family B, member 1|stat-like protein; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Borg JP (1996) [6]
    bait Zambrano N (1997) [2]
    bait Tanahashi H (1999) [6]
    bait Trommsdorff M (1998) [7]
    Affinity Capture-Western
    bait Borg JP (1996) [6]
    bait Guenette SY (1996) [2]
    Two-hybrid
    hit Trommsdorff M (1998) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APBA2
  • D15S1518E
  • HsT16821
  • LIN-10
  • EG321
    		•  The BioGRID Database Seperator X11-like protein|adapter protein X11beta|amyloid beta A4 precursor protein-binding, family A, member 2|neuron-specific X11L protein|neuronal munc18-1-interacting protein 2|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; amyloid beta (A4) precursor protein-binding, family...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Araki Y (2003) [5]
    hit Biederer T (2002) [9]
    Reconstituted Complex
    hit Biederer T (2002) [9]
    bait Tomita S (1999) [2]
    Two-hybrid
    bait Tomita S (1999) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APBA3
  • MGC:15815
  • X11L2
  • mint3
  • EG9546
    		•  The BioGRID Database Seperator X11-like 2 protein|adapter protein X11gamma|amyloid beta (A4) precursor protein-binding, family A, member 3|neuron-specific X11L2 protein|neuronal munc18-1-interacting protein 3|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; amyloid beta (A4) precursor protein-binding, family...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Biederer T (2002) [9]
    Reconstituted Complex
    hit Biederer T (2002) [9]
    hit Tanahashi H (1999) [2]
    Two-hybrid
    hit Tanahashi H (1999) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APBA1
  • D9S411E
  • MINT1
  • X11
  • EG320
    		•  The BioGRID Database Seperator adaptor protein X11alpha|amyloid beta A4 precursor protein-binding, family A, member 1|neuron-specific X11 protein|neuronal munc18-1-interacting protein 1|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Biederer T (2002) [9]
    bait Borg JP (1996) [6]
    Reconstituted Complex
    hit Biederer T (2002) [9]
    bait/hit Borg JP (1996) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FBLN1
  • FBLN
  • EG2192
    		•  The BioGRID Database Seperator OTTHUMP00000028589; fibulin 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Ohsawa I (2001) [3]
    Reconstituted Complex
    bait Ohsawa I (2001) [3]
    Affinity Capture-Western
    hit Ohsawa I (2001) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HADH2
  • 17b-HSD10
  • ABAD
  • ERAB
  • RP3-339A1...
    		•  The BioGRID Database Seperator 17-beta-hydroxysteroid dehydrogenase type 10|3-hydroxy-2-methylbutyryl-CoA dehydrogenase|AB-binding alcohol dehydrogenase|amyloid-beta binding polypeptide|amyloid-beta peptide binding alcohol dehydrogenase|endoplasmic reticulum-associated amyloid-beta peptide binding protein|hydroxyacyl-Coenzyme...
    Gene Ontology: [View List]
    Two-hybrid
    hit Yan SD (1997) [3]
    Reconstituted Complex
    hit Yan SD (1997) [3]
    Affinity Capture-Western
    hit Yan SD (1997) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APPBP2
  • HS.84084
  • KIAA0228
  • PAT1
  • EG10513
    		•  The BioGRID Database Seperator amyloid beta precursor protein (cytoplasmic tail)-binding protein 2|amyloid beta precursor protein-binding protein 2|protein interacting with APP tail 1; amyloid beta precursor protein (cytoplasmic tail) binding protein 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Zheng P (1998) [2]
    Reconstituted Complex
    hit Zheng P (1998) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BLMH
  • BH
  • BMH
  • EG642
    		•  The BioGRID Database Seperator bleomycin hydrolase
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Lefterov IM (2000) [2]
    Co-fractionation
    bait Lefterov IM (2000) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APPBP1
  • A-116A10.1
  • HPP1
  • NAE1
  • EG8883
    		•  The BioGRID Database Seperator NEDD8-activating enzyme E1 subunit|amyloid beta precursor protein binding protein 1, 59kDa|amyloid beta precursor protein-binding protein 1, 59kD|amyloid protein-binding protein 1|protooncogene protein 1; NEDD8 activating enzyme E1 subunit 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Chow N (1996) [2]
    Affinity Capture-Western
    bait Chow N (1996) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAV1
  • CAV
  • MSTP085
  • VIP21
  • EG857
    		•  The BioGRID Database Seperator caveolae protein, 22-kD|caveolin 1|caveolin 1 caveolae protein, 22kD|caveolin 1, alpha isoform|caveolin 1, beta isoform|cell growth-inhibiting protein 32; caveolin 1, caveolae protein, 22kDa
    Gene Ontology: [View List]
    Co-fractionation
    hit Ikezu T (1998) [2]
    Protein-RNA
    hit Ikezu T (1998) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSN
  • DKFZp313L...
  • RP11-477J...
    		•  The BioGRID Database Seperator gelsolin (amyloidosis, Finnish type); gelsolin
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Chauhan VP (1999) [2]
    Affinity Capture-Western
    bait Chauhan VP (1999) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     COL25A1
  • CLAC
  • EG84570
    		•  The BioGRID Database Seperator collagen-like Alzheimer amyloid plaque component|collagenous Alzheimer amyloid plaque component; collagen, type XXV, alpha 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Hashimoto T (2002) [2]
    Co-localization
    bait Hashimoto T (2002) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLSTN1
  • CSTN1
  • KIAA0911
  • PIK3CD
  • EG22883
    		•  The BioGRID Database Seperator alcadein alpha 1|non-classical cadherin XB31alpha1; calsyntenin 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Araki Y (2004) [3]
    hit Araki Y (2003) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCAP31
  • 6C6-AG
  • BAP31
  • CDM
  • EG10134
    		•  The BioGRID Database Seperator B-cell receptor-associated protein 31; accessory protein BAP31
    Gene Ontology: [View List]
    Two-hybrid
    bait Wang B (2003) [2]
    Co-fractionation
    hit Wang B (2003) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Apbb1
  • Fe65
  • Rir
  • EG11785
    		•  The BioGRID Database Seperator amyloid beta (A4) precursor protein-binding, family B, member 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Bressler SL (1996) [4]
    Reconstituted Complex
    hit Bressler SL (1996) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHC1
  • FLJ26504
  • SHC
  • SHCA
  • EG6464
    		•  The BioGRID Database Seperator SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Tarr PE (2002) [2]
    Affinity Capture-Western
    hit Tarr PE (2002) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Apbb1
  • FE65
  • EG29722
    		•  The BioGRID Database Seperator amyloid beta (A4) precursor protein-binding, family B, member 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zambrano N (1997) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HGS
  • HRS
  • ZFYVE8
  • EG9146
    		•  The BioGRID Database Seperator hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Pridgeon JW (2009) [48]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APBB3
  • FE65L2
  • MGC87674
  • SRA
  • EG10307
    		•  The BioGRID Database Seperator FE65-like protein 2|amyloid beta precursor protein-binding, family B, member 3|amyloid precursor interacting protein; amyloid beta (A4) precursor protein-binding, family B, member 3
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Tanahashi H (1999) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BGN
  • DSPG1
  • PG-S1
  • PGI
  • EG633
    		•  The BioGRID Database Seperator biglycan proteoglycan|bone/cartilage proteoglycan-I|dermatan sulphate proteoglycan I|small leucine-rich protein 1A; biglycan
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Snow AD (1995) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CALR
  • RO
  • SSA
  • cC1qR
  • EG811
    		•  The BioGRID Database Seperator Sicca syndrome antigen A (autoantigen Ro; calreticulin)|autoantigen Ro; calreticulin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Johnson RJ () [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAB2
  • DOC-2
  • DOC2
  • FLJ26626
  • EG1601
    		•  The BioGRID Database Seperator disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila); disabled homolog 2|mitogen-responsive phosphoprotein
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Morris SM (2001) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APBB2
  • FE65L
  • FE65L1
  • MGC35575
  • EG323
    		•  The BioGRID Database Seperator amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like); Fe65-like|amyloid beta A4 precursor protein-binding, family B, member 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chang Y (2003) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KNS2
  • KLC
  • KLC1
  • KNS2A
  • EG3831
    		•  The BioGRID Database Seperator kinesin 2 (60-70kD)|kinesin 2 60/70kDa|medulloblastoma antigen MU-MB-2.50; kinesin light chain 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kamal A (2000) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCSTN
  • APH2
  • KIAA0253
  • RP11-517F...
  • EG23385
    		•  The BioGRID Database Seperator ATAG1874|anterior pharynx-defective 2; nicastrin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yu G (2000) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAB1
  • RP6-239D1...
    		•  The BioGRID Database Seperator disabled homolog 1 (Drosophila); disabled homolog 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Homayouni R (1999) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNCB
  • EG6620
    		•  The BioGRID Database Seperator synuclein, beta; beta-synuclein
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Jensen PH (1997) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNCA
  • NACP
  • PARK1
  • PARK4
  • EG6622
    		•  The BioGRID Database Seperator alpha synuclein|alpha-synuclein|alpha-synuclein, isoform NACP140|non A-beta component of AD amyloid|non A4 component of amyloid; synuclein, alpha (non A4 component of amyloid precursor)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Jensen PH (1997) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ACHE
  • YT
  • ARACHE
  • N-ACHE
  • EG43
    		•  The BioGRID Database Seperator acetylcholinesterase|apoptosis-related acetylcholinesterase; acetylcholinesterase (YT blood group)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Cottingham MG (2002) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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