| Name |
Aliases |
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Description |
|
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| CALR |
ROSSAcC1qREG811 |
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Sicca syndrome antigen A (autoantigen Ro; calreticulin)|autoantigen Ro; calreticulin
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| PDIA4 |
ERP70ERP72EG9601 |
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protein disulfide isomerase related protein (calcium-binding protein, intestinal-related)|protein disulfide isomerase-associated 4; protein disulfide isomerase family A, member 4
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| HSPCA |
FLJ31884HSP86HSP90AEG3320 |
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heat shock 90kD protein 1, alpha|heat shock 90kD protein 1, alpha-like 4|heat shock 90kD protein, alpha-like 4|heat shock 90kDa protein 1, alpha; heat shock protein 90kDa alpha (cytosolic), class A member 1
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| SSE1 |
LPG3MSI3YPL106C |
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ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm|Sse1p; protein coding
|
| Biochemical Activity | | | Affinity Capture-Western | | |
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| MTP |
MTTPABLMGC149819EG4547 |
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microsomal triglyceride transfer protein (large polypeptide, 88kD)|microsomal triglyceride transfer protein (large polypeptide, 88kDa)|microsomal triglyceride transfer protein large subunit; microsomal triglyceride transfer protein
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| TRA1 |
ECGPGP96GRP94EG7184 |
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Tumor rejection antigen-1 (gp96)|endothelial cell (HBMEC) glycoprotein|glucose regulated protein, 94 kDa|tumor rejection antigen (gp96) 1; heat shock protein 90kDa beta (Grp94), member 1
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| HSPA5 |
BIPGRP78MIF2EG3309 |
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Heat-shock 70kD protein-5 (glucose-regulated protein, 78kD)|heat shock 70kD protein 5 (glucose-regulated protein, 78kD)|heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
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| LRP2 |
gp330DBSEG4036 |
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Heymann nephritis antigen homolog|calcium sensor protein|megalin; low density lipoprotein-related protein 2
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| UFD1 |
YGR048W |
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Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol|Ufd1p; protein coding
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| KAR2 |
GRP78YJL034W |
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ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p|Kar2p; protein coding
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| QRI8 |
UBC7YMR022W |
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Ubc7p|Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly; protein coding
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| SSM4 |
DOA10KIS3YIL030C |
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Ssm4p|Ubiquitin-protein ligase of the ER/nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation; protein coding
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| SSA1 |
YG100YAL005C |
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ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall|Ssa1p; protein coding
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| HRD1 |
DER3YOL013C |
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Hrd1p|Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; protein coding
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| RPT6 |
CIM3CRL3SCB68YGL048C |
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One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle|Rpt6p; protein coding
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| HSPA1A |
HSP70-1HSP72HSPA1DAQB-147D... |
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dnaK-type molecular chaperone HSP70-1|heat shock 70kD protein 1A|heat shock 70kDa protein 1B|heat shock-induced protein; heat shock 70kDa protein 1A
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| PPIB |
CYP-S1CYPBMGC14109EG5479 |
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PPIase|S-cyclophilin|cyclophilin B|cyclophilin-like protein|peptidyl-prolyl cis-trans isomerase B|peptidylprolyl isomerase B|rotamase; peptidylprolyl isomerase B (cyclophilin B)
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| LDLR |
FHFHCEG3949 |
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low density lipoprotein receptor (familial hypercholesterolemia); LDL receptor|low density lipoprotein receptor
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| LIPC |
HLHTGLLIPHEG3990 |
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lipase, hepatic; lipase C
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| BGN |
DSPG1PG-S1PGIEG633 |
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biglycan proteoglycan|bone/cartilage proteoglycan-I|dermatan sulphate proteoglycan I|small leucine-rich protein 1A; biglycan
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| SEC61B |
EG10952 |
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Sec61 complex, beta subunit|protein translocation complex beta|protein transport protein SEC61 beta subunit; Sec61 beta subunit
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| CANX |
CNXIP90P90EG821 |
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major histocompatibility complex class I antigen-binding protein p88; calnexin
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| SEC61 |
YLR378C |
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Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER|Sec61p; protein coding
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