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BioGRID | Network Layout for APC for Homo sapiens
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APC

 Homo sapiens
The BioGRID Database Seperator
Aliases: DP2, DP2.5, DP3, FAP, GS, EG324
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 20 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with APC

APC was identified with 59 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 CTNNB1
  • CTNNB
  • FLJ25606
  • DKFZp686D...
  • EG1499
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), beta 1 (88kD)|catenin (cadherin-associated protein), beta 1 (88kDa; catenin (cadherin-associated protein), beta 1, 88kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Su LK (1993)
    bait a D (2001)
    bait/hit Davies G (2001)
    bait Ryo A (2001)
    hit Homma MK (2002)
    hit Satoh K (1997)
    Far Western
    hit Su LK (1993)
    Reconstituted Complex
    bait/hit Tickenbrock L (2003)
    bait Eklof Spink K (2001)
    Co-crystal Structure
    bait Eklof Spink K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPRE2
  • EB1
  • EB2
  • RP1
  • EG10982
    		•  The BioGRID Database Seperator APC-binding protein EB1|T-cell activation protein, EB1 family; microtubule-associated protein, RP/EB family, member 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Su LK (1995)
    Reconstituted Complex
    bait Nakamura M (2001)
    hit Su LK (1995)
    Affinity Capture-Western
    hit Su LK (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DLG3
  • KIAA1232
  • MRX
  • NE-Dlg
  • RP11-291O...
    		•  The BioGRID Database Seperator bA291O7.3 (discs, large Drosophila homolog 3 (neuroendocrine-dlg) )|discs large homolog 3|neuroendocrine-dlg|synapse-associated protein 102; discs, large homolog 3 (neuroendocrine-dlg, Drosophila)
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Makino K (1997)
    Reconstituted Complex
    bait Makino K (1997)
    Affinity Capture-Western
    hit Makino K (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSNK2A1
  • CK2A1
  • CKII
  • CKII alpha
  • EG1457
    		•  The BioGRID Database Seperator CK2 catalytic subunit alpha|casein kinase II alpha 1 subunit|casein kinase II alpha subunit|casein kinase II-alpha subunit|protein kinase CK2; casein kinase 2, alpha 1 polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Homma MK (2002)
    Reconstituted Complex
    hit Homma MK (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIFAP3
  • FLJ22818
  • KAP3
  • SMAP
  • EG22920
    		•  The BioGRID Database Seperator small G protein GDP dissociation stimulator|smg GDS-associated protein; kinesin-associated protein 3
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Jimbo T (2002)
    Two-hybrid
    bait/hit Jimbo T (2002)
    Affinity Capture-Western
    bait Jimbo T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APC
  • DP2
  • DP2.5
  • DP3
  • EG324
    		•  The BioGRID Database Seperator adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Su LK (1993)
    Reconstituted Complex
    hit Su LK (1993)
    bait/hit Tickenbrock L (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AXIN1
  • AXIN
  • MGC52315
  • LA16c-314...
    		•  The BioGRID Database Seperator axis inhibition protein 1|axis inhibitor 1|fused, mouse, homolog of; axin 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Nakamura T (1998)
    Two-hybrid
    bait/hit Nakamura T (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIAH1
  • HUMSIAH
  • Siah-1
  • Siah-1a
  • EG6477
    		•  The BioGRID Database Seperator seven in absentia homolog 1|sonic hedgehog (Drosophila) homolog; seven in absentia homolog 1 (Drosophila)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Liu J (2001)
    Affinity Capture-Western
    hit Liu J (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF4
  • ASEF
  • GEF4
  • STM6
  • EG50649
    		•  The BioGRID Database Seperator APC-stimulated guanine nucleotide exchange factor|Rho guanine nucleotide exchange factor 4; Rho guanine nucleotide exchange factor (GEF) 4
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kawasaki Y (2000)
    Affinity Capture-Western
    bait Kawasaki Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUB1
  • BUB1A
  • BUB1L
  • hBUB1
  • EG699
    		•  The BioGRID Database Seperator BUB1 budding uninhibited by benzimidazoles 1 homolog|budding uninhibited by benzimidazoles 1|mitotic spindle checkpoint kinase|putative serine/threonine-protein kinase; BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kaplan KB (2001)
    Biochemical Activity
    bait Kaplan KB (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTNNA1
  • CAP102
  • FLJ36832
  • EG1495
    		•  The BioGRID Database Seperator alpha-E-catenin|alpha-catenin|alphaE-catenin|cadherin-associated protein,102kDa|catenin (cadherin-associated protein), alpha 1 (102kD)|catenin, alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Su LK (1993)
    hit Daniel JM (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JUP
  • CTNNG
  • DP3
  • DPIII
  • EG3728
    		•  The BioGRID Database Seperator catenin (cadherin-associated protein), gamma (80kD)|catenin (cadherin-associated protein), gamma 80kDa|gamma-catenin; junction plakoglobin
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Shibata T (1994)
    Affinity Capture-Western
    hit Daniel JM (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN13
  • DKFZp686J...
  • FAP-1
  • PNP1
  • EG5783
    		•  The BioGRID Database Seperator APO-1/CD95 (Fas)-associated phosphatase|Fas-associated phosphatase-1|protein tyrosine phosphatase 1E|protein tyrosine phosphatase, non-receptor type 13|protein tyrosine phosphatase, nonreceptor type 13|protein-tyrosine phosphatase 1, Fas-associated|protein-tyrosine phosphatase PTPL1; protein...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Erdmann KS (2000)
    Two-hybrid
    hit Erdmann KS (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSNK2B
  • CK2B
  • CK2N
  • CSK2B
  • EG1460
    		•  The BioGRID Database Seperator Casein kinase II beta subunit|alternative name: G5a, phosvitin|phosvitin; casein kinase 2, beta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Homma MK (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TUBA1
  • FLJ30169
  • H2-ALPHA
  • TUBA4A
  • EG7277
    		•  The BioGRID Database Seperator tubulin alpha-1 chain|tubulin, alpha 1 (testis specific); tubulin, alpha 4a
    Gene Ontology: [View List]
    Co-localization
    hit Zumbrunn J (2001)
    Reconstituted Complex
    hit Zumbrunn J (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TFAP2A
  • AP-2
  • AP2TF
  • TFAP2
  • EG7020
    		•  The BioGRID Database Seperator activating enhancer-binding protein 2 alpha|transcription factor AP-2 alpha|transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha); transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Li Q (2004)
    Reconstituted Complex
    bait Li Q (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XPO1
  • CRM1
  • DKFZp686B...
  • EG7514
    		•  The BioGRID Database Seperator CRM1, yeast, homolog|Exportin-1 (required for chromosome region maintenance)|exportin 1|exportin 1 (CRM1, yeast, homolog); exportin 1 (CRM1 homolog, yeast)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Tickenbrock L (2002)
    Reconstituted Complex
    bait/hit Tickenbrock L (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AXIN2
  • AXIL
  • DKFZp781B...
  • MGC126582
  • EG8313
    		•  The BioGRID Database Seperator axin 2 (conductin, axil); axin 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait von Kries JP (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Axin1
  • Axin
  • EG79257
    		•  The BioGRID Database Seperator GSK-3beta interacting protein rAxin; axin 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Kishida S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUB3
  • BUB3L
  • hBUB3
  • EG9184
    		•  The BioGRID Database Seperator BUB3 budding uninhibited by benzimidazoles 3|budding uninhibited by benomyl|mitotic checkpoint component; BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kaplan KB (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAD2L1
  • HSMAD2
  • MAD2
  • EG4085
    		•  The BioGRID Database Seperator MAD2 (mitotic arrest deficient, yeast, homolog)-like 1|MAD2-like 1|MAD2-like protein 1|mitotic arrest deficient, yeast, homolog-like 1; MAD2 mitotic arrest deficient-like 1 (yeast)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Fang G (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUB1B
  • BUB1beta
  • BUBR1
  • Bub1A
  • EG701
    		•  The BioGRID Database Seperator BUB1 budding uninhibited by benzimidazoles 1 homolog beta|MAD3/BUB1-related protein kinase|budding uninhibited by benzimidazoles 1 (yeast homolog), beta; BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)
    Gene Ontology: [View List]
    Biochemical Activity
    bait Kaplan KB (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SFN
  • YWHAS
  • EG2810
    		•  The BioGRID Database Seperator 14-3-3 sigma; stratifin
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Benzinger A (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MUC1
  • CD227
  • EMA
  • H23AG
  • EG4582
    		•  The BioGRID Database Seperator DF3 antigen|H23 antigen|MUC-1/SEC|MUC-1/X|MUC1 isoform T10|MUC1 isoform T11|MUC1 isoform T12|MUC1 isoform T13|MUC1/ZD|breast carcinoma-associated antigen DF3|episialin|mucin 1|mucin 1, transmembrane|peanut-reactive urinary mucin|polymorphic epithelial mucin|tumor associated epithelial mucin;...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Hattrup CL (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP2R5A
  • MGC131915
  • B56A
  • PR61A
  • EG5525
    		•  The BioGRID Database Seperator PP2A, B subunit, B' alpha isoform|PP2A, B subunit, B56 alpha isoform|PP2A, B subunit, PR61 alpha isoform|PP2A, B subunit, R5 alpha isoform|protein phosphatase 2, regulatory subunit B (B56), alpha isoform|serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform; protein...
    Gene Ontology: [View List]
    Co-localization
    hit Galea MA (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSK3B
  • EG2932
    		•  The BioGRID Database Seperator glycogen synthase kinase 3 beta; GSK3beta isoform
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Davies G (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPRE1
  • EB1
  • MGC117374
  • MGC129946
  • EG22919
    		•  The BioGRID Database Seperator microtubule-associated protein, RP/EB family, member 1; adenomatous polyposis coli-binding protein EB1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Askham JM (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DLGAP1
  • DAP-1
  • DAP-1-ALPHA
  • DAP-1-BETA
  • EG9229
    		•  The BioGRID Database Seperator PSD-95/SAP90 binding protein 1|SAP90/PSD-95-associated protein 1|discs large homolog-associated protein 1|disks large-associated protein 1|guanylate kinase-associated protein; discs, large (Drosophila) homolog-associated protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Satoh K (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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