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BioGRID | Network Layout for AKT1 for Homo sapiens
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AKT1

 Homo sapiens
The BioGRID Database Seperator
Aliases: MGC99656, PKB, PRKBA, RAC, RAC-ALPHA, AKT, EG207
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: RAC-alpha serine/threonine-protein kinase|murine thymoma viral (v-akt) oncogene homolog-1|protein kinase B|rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 18 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with AKT1

AKT1 was identified with 103 protein interactions and 1 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 TCL1A
  • TCL1
  • EG8115
    		•  The BioGRID Database Seperator T-cell lymphoma-1|T-cell lymphoma-1A; T-cell leukemia/lymphoma 1A
    Gene Ontology: [View List]
    Invivo
    hit Laine J (2000)
    hit French SW (2002)
    Invitro
    hit Laine J (2000)
    hit French SW (2002)
    Two-hybrid
    hit Laine J (2000)
    hit French SW (2002)
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    bait Laine J (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSPCA
  • FLJ31884
  • HSP86
  • HSP90A
  • EG3320
    		•  The BioGRID Database Seperator heat shock 90kD protein 1, alpha|heat shock 90kD protein 1, alpha-like 4|heat shock 90kD protein, alpha-like 4|heat shock 90kDa protein 1, alpha; heat shock protein 90kDa alpha (cytosolic), class A member 1
    Gene Ontology: [View List]
    Invivo
    hit Sato S (2000)
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    bait Haendeler J (2003)
    hit Kawauchi K (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IMPDH2
  • IMPD2
  • IMPDH-II
  • EG3615
    		•  The BioGRID Database Seperator IMP dehydrogenase 2|IMP oxireductase 2|inosine 5' phosphate dehydrogenase 2|inosine monophosphate dehydrogenase 2|inosine monophosphate dehydrogenase type II|inosine monophosphate oxireductase 2; IMP (inosine monophosphate) dehydrogenase 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Two-hybrid
    hit Ingley E (2000)
    Reconstituted Complex
    bait Ingley E (2000)
    Affinity Capture-Western
    hit Ingley E (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NR4A1
  • GFRP1
  • HMR
  • MGC9485
  • EG3164
    		•  The BioGRID Database Seperator TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|orphan nuclear receptor HMR|steroid receptor TR3; nuclear receptor subfamily 4, group A, member 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    hit Pekarsky Y (2001)
    Biochemical Activity
    hit Pekarsky Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FTS
  • FT1
  • AKTIP
  • EG64400
    		•  The BioGRID Database Seperator AKT interacting protein; fused toes homolog
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    hit Remy I (2004)
    Reconstituted Complex
    bait/hit Remy I (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PKN2
  • MGC71074
  • PRK2
  • PRKCL2
  • EG5586
    		•  The BioGRID Database Seperator cardiolipin-activated protein kinase Pak2|protein kinase C-like 2; protein kinase N2
    Gene Ontology: [View List]
    Invivo
    hit Koh H (2000)
    Invitro
    hit Koh H (2000)
    Two-hybrid
    hit Koh H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Biochemical Activity
    hit Zimmermann S (1999)
    Affinity Capture-Western
    bait Zimmermann S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FRAP1
  • FRAP
  • FRAP2
  • MTOR
  • EG2475
    		•  The BioGRID Database Seperator FK506 binding protein 12-rapamycin associated protein 2|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1|dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1)|rapamycin associated protein FRAP2|rapamycin target protein; FK506 binding protein 12-rapamycin...
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Sarbassov DD (2005)
    hit ć A (2000)
    Protein-peptide
    hit Cheng SW (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCZ
  • PKC2
  • EG5590
    		•  The BioGRID Database Seperator protein kinase C, zeta; OTTHUMP00000044160
    Gene Ontology: [View List]
    Invivo
    hit Doornbos RP (1999)
    Invitro
    hit Doornbos RP (1999)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSC2
  • LAM
  • TSC4
  • FLJ43106
  • EG7249
    		•  The BioGRID Database Seperator tuberous sclerosis 2; tuberin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Dan HC (2002)
    bait Roux PP (2004)
    Reconstituted Complex
    hit Dan HC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K11
  • MGC17114
  • MLK-3
  • MLK3
  • EG4296
    		•  The BioGRID Database Seperator SH3 domain-containing proline-rich kinase|mixed lineage kinase 3|protein-tyrosine kinase PTK1; mitogen-activated protein kinase kinase kinase 11
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Barthwal MK (2003)
    Reconstituted Complex
    bait Barthwal MK (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MTCP1
  • C6.1B
  • GS1-273L2...
    		•  The BioGRID Database Seperator mature T-cell proliferation 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    bait Laine J (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K4
  • JNKK
  • JNKK1
  • MAPKK4
  • EG6416
    		•  The BioGRID Database Seperator JNK activating kinase 1|JNK-activated kinase 1|MAP kinase kinase 4|MAPK/ERK kinase 4|SAPK/ERK kinase 1|c-Jun N-terminal kinase kinase 1|dual specificity mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Park HS (2002)
    Biochemical Activity
    hit Park HS (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AR
  • AIS
  • DHTR
  • HUMARA
  • RP11-383C...
    		•  The BioGRID Database Seperator androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease); OTTHUMP00000061928|androgen receptor|dihydrotestosterone receptor
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Lin HK (2001)
    Affinity Capture-Western
    hit Lin HK (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCQ
  • PRKCT
  • nPKC-theta
  • MGC126514
  • RP11-563J...
    		•  The BioGRID Database Seperator OTTHUMP00000043364|OTTHUMP00000043365; protein kinase C, theta
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Bauer B (2001)
    Affinity Capture-Western
    bait Bauer B (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRT10
  • CK10
  • K10
  • KPP
  • EG3858
    		•  The BioGRID Database Seperator keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); cytokeratin 10|keratin 10
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Paramio JM (2001)
    Two-hybrid
    hit Paramio JM (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK14
  • CSBP1
  • CSBP2
  • CSPB1
  • RP1-179N1...
    		•  The BioGRID Database Seperator Csaids binding protein|MAP kinase Mxi2|MAX-interacting protein 2|cytokine suppressive anti-inflammatory drug binding protein|p38 MAP kinase|p38 mitogen activated protein kinase|p38alpha Exip|stress-activated protein kinase 2A; mitogen-activated protein kinase 14
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Rane MJ (2001)
    Biochemical Activity
    bait Rane MJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRAF
  • B-raf 1
  • BRAF1
  • RAFB1
  • EG673
    		•  The BioGRID Database Seperator 94 kDa B-raf protein|Murine sarcoma viral (v-raf) oncogene homolog B1; v-raf murine sarcoma viral oncogene homolog B1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Guan KL (2000)
    Biochemical Activity
    hit Guan KL (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSC1
  • KIAA0243
  • LAM
  • MGC86987
  • EG7248
    		•  The BioGRID Database Seperator hamartin|tuberous sclerosis 1 protein|tumor suppressor; tuberous sclerosis 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Roux PP (2004)
    hit Dan HC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDKN1B
  • CDKN4
  • KIP1
  • P27KIP1
  • EG1027
    		•  The BioGRID Database Seperator cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor 1B
    Gene Ontology: [View List]
    Biochemical Activity
    hit Fujita N (2002)
    Affinity Capture-Western
    bait Fujita N (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRIB3
  • C20orf97
  • NIPK
  • SINK
  • EG57761
    		•  The BioGRID Database Seperator neuronal cell death inducible putative kinase|p65-interacting inhibitor of NF-kappaB|tribbles 3; tribbles homolog 3 (Drosophila)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Du K (2003)
    Affinity Capture-Western
    bait Du K (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ILK
  • DKFZp686F...
  • P59
  • EG3611
    		•  The BioGRID Database Seperator integrin-linked kinase
    Gene Ontology: [View List]
    Invitro
    bait Delcommenne M (1998)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDPK1
  • MGC20087
  • MGC35290
  • PDK1
  • EG5170
    		•  The BioGRID Database Seperator 3-phosphoinositide dependent protein kinase-1; PkB kinase like gene 1|protein kinase
    Gene Ontology: [View List]
    Invivo
    bait Barry FA (2002)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAZ
  • KCIP-1
  • MGC111427
  • MGC126532
  • EG7534
    		•  The BioGRID Database Seperator 14-3-3 protein/cytosolic phospholipase A2|14-3-3 zeta|phospholipase A2|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
    Gene Ontology: [View List]
    Invivo
    bait Powell DW (2002)
    Invitro
    bait Powell DW (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TCL1B
  • TML1
  • EG9623
    		•  The BioGRID Database Seperator T-cell lymphoma/leukemia 1B|TCL1/ MTCP1-like 1; T-cell leukemia/lymphoma 1B
    Gene Ontology: [View List]
    Invivo
    bait Laine J (2000)
    Two-hybrid
    bait Laine J (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLXNA1
  • NOV
  • NOVP
  • PLEXIN-A1
  • EG5361
    		•  The BioGRID Database Seperator plexin A1; plexin 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Turner LJ (2004)
    Reconstituted Complex
    bait Turner LJ (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EG253260
  • DKFZp686B...
  • KIAA1999
  • MGC39830
    		•  The BioGRID Database Seperator rapamycin-insensitive companion of mTOR; TORC2-specific protein AVO3|pianissimo
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Sarbassov DD (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAD
  • BBC2
  • BCL2L8
  • EG572
    		•  The BioGRID Database Seperator BCL-X/BCL-2 binding protein|BCL2-antagonist of cell death protein|BCL2-binding component 6|BCL2-binding protein; BCL2-antagonist of cell death
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Wang X (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPKAP1
  • MGC2745
  • SIN1
  • SIN1b
  • RP11-269P...
    		•  The BioGRID Database Seperator MEKK2-interacting protein 1|OTTHUMP00000064207|SAPK-interacting protein 1|ras inhibitor MGC2745|stress-activated map kinase interacting protein 1|stress-activated protein kinase-interacting 1; mitogen-activated protein kinase associated protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Jacinto E (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHUK
  • IKBKA
  • IKK-alpha
  • IKK1
  • EG1147
    		•  The BioGRID Database Seperator I-kappa-B kinase 1|I-kappa-B kinase-alpha|IKK-a kinase|IkB kinase alpha subunit|Nuclear factor NFkappaB inhibitor kinase alpha|conserved helix-loop ubiquitous kinase; conserved helix-loop-helix ubiquitous kinase
    Gene Ontology: [View List]
    Invivo
    bait Ozes ON (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMAD7
  • MADH7
  • MADH8
  • FLJ16482
  • EG4092
    		•  The BioGRID Database Seperator MAD (mothers against decapentaplegic, Drosophila) homolog 7|MAD, mothers against decapentaplegic homolog 7|Mothers against decapentaplegic, drosophila, homolog of, 7|SMAD, mothers against DPP homolog 7; SMAD family member 7
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Song K (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KB1
  • PS6K
  • S6K
  • S6K1
  • EG6198
    		•  The BioGRID Database Seperator p70 S6 kinase, alpha 1|p70 S6 kinase, alpha 2|ribosomal protein S6 kinase, 70kD, polypeptide 1|serine/threonine kinase 14 alpha; ribosomal protein S6 kinase, 70kDa, polypeptide 1
    Gene Ontology: [View List]
    Co-purification
    bait Berven LA (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSK3B
  • EG2932
    		•  The BioGRID Database Seperator glycogen synthase kinase 3 beta; GSK3beta isoform
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Thimmaiah KN (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CARHSP1
  • CRHSP-24
  • CSDC1
  • MGC111446
  • EG23589
    		•  The BioGRID Database Seperator calcium regulated heat stable protein 1 (24kD)|calcium-regulated heat-stable protein (24kD)|calcium-regulated heat-stable protein 1; calcium regulated heat stable protein 1, 24kDa
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Auld GC (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTMP
  • MGC29636
  • THEM4
  • EG117145
    		•  The BioGRID Database Seperator thioesterase superfamily member 4; C-terminal modulator protein
    Gene Ontology: [View List]