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ABCA1
Homo sapiens
Aliases:
FLJ14958, HDLDT1, ABC1, ABC-1, MGC164864, CERP, MGC165011, TGD
Description:
ATP-binding cassette, sub-family A (ABC1), member 1
Links:
[UniprotKB]
|
[HPRD]
|
[OMIM]
|
[Entrez Gene]
Gene Ontology:
30 total GO annotations for this record.
[view list]
Function
Process
Component
•
small GTPase binding
(
IPI
)
•
cholesterol binding
(
IC
)
•
apolipoprotein A-I recept ...
(
IDA
)
•
anion transmembrane trans ...
(
ISS
)
•
phospholipid transporter ...
(
IDA
)
•
cholesterol transporter a ...
(
IDA
)
•
syntaxin-13 binding
(
IPI
)
•
phospholipid binding
(
IC
)
•
cholesterol efflux
(
IDA
)
•
negative regulation of fo ...
(
TAS
)
•
G-protein coupled recepto ...
(
IMP
)
•
negative regulation of ch ...
(
TAS
)
•
reverse cholesterol trans ...
(
IMP
)
•
lysosome organization
(
IDA
)
•
intracellular cholesterol ...
(
IMP
)
•
positive regulation of cA ...
(
IMP
)
•
phospholipid efflux
(
IMP
)
•
phospholipid efflux
(
IDA
)
•
phospholipid homeostasis
(
IMP
)
•
cholesterol homeostasis
(
IDA
)
•
Cdc42 protein signal tran ...
(
IMP
)
•
cholesterol efflux
(
IMP
)
•
endosome transport
(
IDA
)
•
platelet dense granule or ...
(
IMP
)
•
interleukin-1 beta secret ...
(
IMP
)
•
high-density lipoprotein ...
(
IMP
)
•
membrane raft
(
IDA
)
•
phagocytic vesicle
(
IDA
)
•
integral to plasma membra ...
(
IDA
)
•
membrane fraction
(
IDA
)
Download interactions associated with ABCA1
ABCA1 was identified with
12
protein interactions
Name
Aliases
Description
Evidence Code
Role
Source [Interactions]
FADD
MGC8528
MORT1
GIG3
Fas-associating death domain-containing protein
Gene Ontology:
[View List]
Two-hybrid
hit
Buechler C (2002)
[
3
]
Reconstituted Complex
bait/hit
Buechler C (2002)
[
3
]
XPC
RAD4
XPCC
XP3
xeroderma pigmentosum, complementation group C
Gene Ontology:
[View List]
Reconstituted Complex
hit
Shimizu Y (2003)
[
3
]
Two-hybrid
bait/hit
Shimizu Y (2003)
[
3
]
SNTB2
EST25263
D16S2531E
SNTL
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Gene Ontology:
[View List]
Two-hybrid
hit
Buechler C (2002)
[
6
]
Affinity Capture-Western
bait
Buechler C (2002)
[
6
]
AOX1
AOH1
AO
aldehyde oxidase 1
Gene Ontology:
[View List]
Two-hybrid
hit
Buechler C (2002)
[
6
]
PRPF8
PRP8
PRPC8
HPRP8
U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
Gene Ontology:
[View List]
Two-hybrid
hit
Buechler C (2002)
[
6
]
SDHB
SDH1
PGL4
SDH
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Gene Ontology:
[View List]
Two-hybrid
hit
Buechler C (2002)
[
6
]
UGP1
UGPP1
Uridyl diphosphate glucose pyrophosphorylase-1
Gene Ontology:
[View List]
Two-hybrid
hit
Buechler C (2002)
[
6
]
CREBBP
CBP
RSTS
KAT3A
CREB binding protein
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Tini M (2002)
[
9
]
APOA1
MGC117399
apolipoprotein A-I
Gene Ontology:
[View List]
Reconstituted Complex
bait/hit
Fitzgerald ML (2002)
[
2
]
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.